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Diagenic Announces Launch of First Breast Cancer Gene-Expression Blood Test
Date:11/10/2008

) at a special event in New Delhi. Speaking at the launch, DiaGenic CEO Erik Christensen, M.D. Ph.D., said that the company decided to launch the test in India because of the interest generated by its large clinical study across the country, which confirmed the test's gene signature is unaffected by ethnic variation.

"We hope that by introducing a test that uses peripheral blood rather than tissue from the actual breast, more women will be encouraged to come forward for testing," said Dr. Christensen. "In addition, we see BCtect(TM) filling a gap where mammography is not readily available."

More details on the selection of India as the first market for the new product were given by Praveen Sharma, Ph.D., co-founder of DiaGenic. "The results from our Indian study showed that the gene set, previously identified in Scandinavian and US cohorts, also had similar good diagnostic and predictive performance in the Indian population. BCtect(TM) is not affected by ethnic variation or menopausal state of the patient, allowing for widespread use to diagnose breast cancer at an early stage."

The TaqMan Array manufactured for DiaGenic by Applied Biosystems consists of 96 TaqMan(R) Gene Expression Assays pre-loaded multiple times on a 384-well micro fluidic card. These 384 simultaneous real-time PCR reactions are performed without the need to use liquid-handling robots or multichannel pipettors. The array is run on the Applied Biosystems 7900HT Fast Real-time PCR System by Labindia.

"We continue to demonstrate our commitment to providing scientists with the molecular tools they need to develop important diagnostics," said Peter Dansky, president of Applied Biosystems' functional analysis division.

"The TaqMan Arrays provide an ideal format for surveying gene expression markers based in their easy-to-use format, high sensitivity, and ability to facilitate standardization among laboratories for consistent and reliable results."

The DiaGenic
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SOURCE DiaGenic ASA and Applied Biosystems Inc.
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