Navigation Links
Diagenic Announces Launch of First Breast Cancer Gene-Expression Blood Test
Date:11/10/2008

India Chosen as First Commercial Market to Demonstrate Test's Potential for

Rapid Uptake

OSLO and FOSTER CITY, California, November 10 /PRNewswire-FirstCall/ -- DiaGenic ASA (OSL: DIAG) and Applied Biosystems Inc. (NYSE: ABI) today announced the launch of BCtect(TM), a blood-based test for early detection of breast cancer. The test searches for a unique gene expression signature identified by DiaGenic using a custom TaqMan(R) Array manufactured for DiaGenic by Applied Biosystems. India was chosen as the first country for the introduction of BCtect(TM) after successful completion of a large study in the country.

The DiaGenic BCtect(TM) test addresses a significant medical need in India, where breast cancer is the second leading cause of death among women. The lack of a coordinated national screening program means that breast cancer is typically detected at a late stage, resulting in high mortality rates compared to Western countries. Last year alone, nearly 100,000 women in the country died from the disease. Breast cancer is also on the rise, with an estimated 250,000 new cases expected in India by 2015. A key problem has been the detection of only 10% of cases at an early stage, which lags far behind Western countries where detection rates reach as high as 65%.

Studies show there is more than a 90% chance of surviving breast cancer if detected at an early stage, whereas the mortality rate reaches 90% if this disease is caught at a very late stage. Clinical studies performed on a group of Indian women by DiaGenic have shown that the test can detect tumors early and accurately, in particular among younger (pre-menopausal) women and those with dense breasts.

DiaGenic launched BCtect(TM) at a special event in New Delhi. Speaking at the launch, DiaGenic CEO Erik Christensen, M.D. Ph.D., said that the company decided to launch the test in India because of the interest generated by its large clinical study across the country, which confirmed the test's gene signature is unaffected by ethnic variation.

"We hope that by introducing a test that uses peripheral blood rather than tissue from the actual breast, more women will be encouraged to come forward for testing," said Dr. Christensen. "In addition, we see BCtect(TM) filling a gap where mammography is not readily available."

More details on the selection of India as the first market for the new product were given by Praveen Sharma, Ph.D., co-founder of DiaGenic. "The results from our Indian study showed that the gene set, previously identified in Scandinavian and US cohorts, also had similar good diagnostic and predictive performance in the Indian population. BCtect(TM) is not affected by ethnic variation or menopausal state of the patient, allowing for widespread use to diagnose breast cancer at an early stage."

The TaqMan Array manufactured for DiaGenic by Applied Biosystems consists of 96 TaqMan(R) Gene Expression Assays pre-loaded multiple times on a 384-well micro fluidic card. These 384 simultaneous real-time PCR reactions are performed without the need to use liquid-handling robots or multichannel pipettors. The array is run on the Applied Biosystems 7900HT Fast Real-time PCR System by Labindia.

"We continue to demonstrate our commitment to providing scientists with the molecular tools they need to develop important diagnostics," said Peter Dansky, president of Applied Biosystems' functional analysis division.

"The TaqMan Arrays provide an ideal format for surveying gene expression markers based in their easy-to-use format, high sensitivity, and ability to facilitate standardization among laboratories for consistent and reliable results."

The DiaGenic BCtect(TM) breast cancer test will be marketed in India through Religare SRL (formerly known as SRL Ranbaxy), the largest laboratory chain in South East Asia. Sanjeev K. Chaudhry, M.D, CEO of SRL predicts high demand for the DiaGenic test.

"We believe that BCtect(TM) will provide the perfect incentive for women to take charge of their health and undergo regular check-ups," said Dr. Chaudhry. "Religare SRL will put in place intensive and extensive market-facing strategies to ensure rapid growth in the market, both locally and internationally, and will invest substantial amounts and efforts to inform the market on the availability of this new innovative test."

Corporate Inquiries

Erik Christensen, Managing Director

DiaGenic ASA, Grenseveien 92, NO-0663 Oslo, Norway

Tel +47-95939918 Email: erik.christensen@diagenic.com

Media Inquiries

For Applied Biosystems:

Renaldo Juanso

Applied Biosystems

Tel +1-650-638-5354 Email: renaldo.juanso@appliedbiosystems.com


'/>"/>
SOURCE DiaGenic ASA and Applied Biosystems Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
5. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
6. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
7. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
8. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
9. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
10. Genta Incorporated Announces Second Quarter 2007 Financial Results and Corporate Highlights
11. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... , May 24, 2016 ... beide primären Endpunkte und demonstriert ... in ‚ausgezeichneter plus guter , ...    ,      (Logo: http://photos.prnewswire.com/prnh/20130829/633895-a ... heute neue positive Daten von der MORA-Studie der ...
(Date:5/24/2016)... New Zealand , May 24, 2016 ... and informatics solutions for the healthcare sector, has been named ... New Zealand Hi-Tech Awards 2016. Dr Bruce ... fantastic acknowledgement for our team.  It,s really good to be ... burden healthcare internationally. Our products are used in 35 countries ...
(Date:5/24/2016)... May 24, 2016  Joe Marziani has joined VMS BioMarketing as senior vice president ... today. In his new role, Marziani will lead the company,s business development and sales ... improve outcomes. Photo - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
Breaking Medicine Technology:
(Date:5/26/2016)... ... , ... On Memorial Day, Hope For Heroes and USA Medical ... for the country. The nonprofit Hope For Heroes partnered with the leading provider ... for disabled military veterans, as well as police, firemen, and EMS professionals across the ...
(Date:5/26/2016)... ... May 26, 2016 , ... Cardiac arrhythmia is ... impact on long-term patient survival, reports a team of UPMC researchers in the ... in the Journal of Thoracic and Cardiovascular Surgery, provide critical information that will ...
(Date:5/26/2016)... Hampshire (PRWEB) , ... May 26, 2016 , ... MadgeTech ... are designed, engineered, and manufactured in Warner, New Hampshire at the MadgeTech headquarters. With ... provide reliable monitoring solutions trusted by government agencies, including NASA. , In 2012, ...
(Date:5/26/2016)... ... May 26, 2016 , ... Dr. James Maisel will ... Long Island Chapter on June 4, 2016, 1:30-3:30 pm at the Farmingdale Public ... Retina Group of New York , is a Board Certified ophthalmologist who ...
(Date:5/26/2016)... ... 26, 2016 , ... In an effort to provide hair restoration information to the widest possible ... those who do not use the app. Dr. Mohebi, the founder of Parsa Mohebi Hair ... Live . , Dr. Mohebi says, “The positive response to the Snapchat videos we ...
Breaking Medicine News(10 mins):