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Diabetes Research Institute Tests BioHub Mini Organ to Restore Natural Insulin Production in Type 1 Diabetes
Date:3/5/2013

pment of a mini organ would mimic the native pancreas and restore the natural metabolic function of insulin release in immediate response to blood sugar levels-something currently unavailable to patients with diabetes," said Jay Skyler , M.D., deputy director of clinical research and academic programs at the DRI.

"If we can identify an optimal place within the body to place a BioHub, then I believe this disease is totally reversible, which has been the DRI's ultimate goal since our inception," adds Luca Inverardi, M.D., deputy director of translational research.

The components that comprise the BioHub are in various stages of development and testing, with pre-clinical trials currently underway. Research on the DRI BioHub platform is supported through numerous sources, including but not limited to the Diabetes Research Institute Foundation, JDRF, The Leona M. and Harry B. Helmsley Charitable Trust, National Institutes of Health, NIH Small Business Innovation Research (SBIR), University of Miami, pharmaceutical companies, both foreign and domestic, and additional corporate and philanthropic partners. For more information on the development of the BioHub, visit www.DiabetesResearch.org/BioHub.

About the Diabetes Research Institute
The Diabetes Research Institute leads the world in cure-focused research. As the largest and most comprehensive research center dedicated to curing diabetes, the DRI is aggressively working to shrink the timeline toward the discovery of a biological cure for this disease. 

The DRI has made significant contributions to the field of diabetes, pioneering many of the techniques used in diabetes centers around the world. Having already shown that diabetes can be reversed through islet transplantation, the DRI is building upon these promising outcomes by bridging cell-based therapies with emerging technologies. The DRI al
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SOURCE Diabetes Research Institute Foundation
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