Navigation Links
Diabetes Gene Raises Odds of Lower Birth Weight
Date:7/29/2009

PHILADELPHIA, July 29 /PRNewswire-USNewswire/ -- Pediatric researchers have found that a gene previously shown to be involved in the development of type 2 diabetes also predisposes children to having a lower birth weight. The finding sheds light on a possible genetic influence on how prenatal events may set the stage for developing diabetes in later childhood or adulthood.

Researchers from The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine published the study July 10 in the online version of the journal Diabetes.

"It's a bit unusual to find a gene linked to both prenatal events and to a disease that occurs later in life," said study leader Struan F.A. Grant, Ph.D., a researcher at the Center for Applied Genomics of The Children's Hospital of Philadelphia. "This gene variant carries a double whammy, in raising the risk of both lower birth weight and the development of type 2 diabetes in later life."

Type 2 diabetes occurs either when the pancreas produces too little insulin or when the body cannot efficiently use the insulin that is produced. Formerly called adult-onset diabetes and still most common in adults, type 2 diabetes has been increasing sharply among children.

Grant and study co-leader Hakon Hakonarson, Ph.D., director of the Center for Applied Genomics at Children's Hospital, investigated 20 gene locations previously reported to be associated with type 2 diabetes. Drawing on a cohort of some 5,700 Caucasian children in an ongoing genome-wide association study of childhood obesity at Children's Hospital, the researchers compared birth weights with the occurrence of the 20 gene variants.

They found that one of the gene variants, called CDKAL1, had a strong association with lower birth weight -- a finding that supports the so-called fetal insulin hypothesis. Pr
'/>"/>

SOURCE The Children's Hospital of Philadelphia
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. S.C. Medical Home Pilot for Diabetes Enrolls 1,110
2. Takeda Receives FDA Complete Response Letter for Alogliptin, an Investigational Treatment for Type 2 Diabetes
3. MacroGenics and Lilly Achieve Targeted Patient Enrollment in PROTEGE, a Global Phase 2/3 Clinical Trial of Teplizumab in Type 1 Diabetes
4. Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions
5. FYI From Human Genome Sciences: GlaxoSmithKline Study Shows GSKs Novel Diabetes Treatment Syncria(R) (Albiglutide) Improves Glucose Control, Reduces Weight
6. Tolerx Presents Data at 69th Scientific Sessions of the American Diabetes Association
7. Research: Popular Diabetes Medications Associated with Increase in Bone Fractures
8. SCAI Statement on the BARI 2D Trial (Bypass Angioplasty Revascularization Investigation With Diabetes Trial) Presented at the American Diabetes Association (ADA) Annual Scientific Sessions and Published in The New England Journal of Medicine
9. Study Shows GSKs Novel Diabetes Treatment SYNCRIA(R) (albiglutide) Improves Glucose Control and Reduces Weight
10. Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients
11. Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/6x789c/new_eu ) ... Pharmacovigilance Legislation (London, UK - November 16-17, 2015)" ... new EU modules concerning Pharmacovigilance are a major departure ... Europe . The intention of the ... requirements, examine how they overlap and fit together and ...
(Date:9/2/2015)... Calif. , Sept. 2, 2015  ArmaGen, ... developing revolutionary therapies to treat severe neurological disorders, ... dosed in its multi-center Phase 1/2a clinical trial ... I (MPS I). AGT-181 is ... treatment of MPS I. The most severe form ...
(Date:9/2/2015)... , September 2, 2015 Elekta, a ... cancer survivorship on September 10, 6:30-8:30 p.m., at Elekta,s North ... Ultimate Ride to Survivorship " will feature Professional BMX athlete, ... of a brain tumor with Leksell Gamma Knife®, Elekta,s radiosurgery ... new cancer cases will be diagnosed in Georgia ...
Breaking Medicine Technology:ArmaGen Announces First Patient Dosed in Phase 1/2a Clinical Trial of AGT-181 for the Treatment of Hurler Syndrome 2ArmaGen Announces First Patient Dosed in Phase 1/2a Clinical Trial of AGT-181 for the Treatment of Hurler Syndrome 3ArmaGen Announces First Patient Dosed in Phase 1/2a Clinical Trial of AGT-181 for the Treatment of Hurler Syndrome 4Elekta to Host Cancer Survivorship Event at Company's Learning and Innovation Center (LINC) in Atlanta 2Elekta to Host Cancer Survivorship Event at Company's Learning and Innovation Center (LINC) in Atlanta 3
... Feb. 17, 2011 Delcath Systems, Inc. (Nasdaq: ... Company has achieved ISO 13485:2003 Certification—an internationally recognized ... manufacturers have the necessary comprehensive management systems in ... medical devices in the European Union (EU). ISO ...
... JOSE, Calif., Feb. 17, 2011 Stryker Corporation,s ... latest innovations in tissue-preserving hip arthroscopy at the ... in San Diego, CA, February 15-19, 2011. The ... Hip Arthroscopy Platform, a comprehensive system of instrumentation ...
Cached Medicine Technology:Delcath Achieves ISO 13485 Certification 2Stryker Features Tissue-Preservation Hip Arthroscopy Platform, Sponsors Surgeon Education Events at the AAOS Annual Meeting 2
(Date:9/2/2015)... MD (PRWEB) , ... September 02, 2015 , ... ... the ambulatory healthcare industry announced today the launch of its enhanced, cloud-based mobile ... RxNT’s “new look” and focus on improving prescriber usability. A leader in health ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... intermediate or final products. Automating sample handling makes density measurements more efficient and ... each step of the automated workflow and the advantages compared to manual sample ...
(Date:9/2/2015)... , ... September 02, 2015 , ... ... clinical and academic partnership has earned international recognition as a premier center for ... that can cause sudden, catastrophic internal bleeding and stroke. , Cure HHT, ...
(Date:9/2/2015)... (PRWEB) , ... September 02, 2015 , ... Ericson is ... CDI Education Director for HCPro and Associate Director of Education for the Association for ... Advancing CDI and ICD-10 for CDI Boot Camps. She serves as a CDI subject ...
(Date:9/2/2015)... IL (PRWEB) , ... September 02, 2015 , ... ... is officially announced today. The two day international investment and business conference will ... Oct 9-11, 2015 in Beijing China. The full-weekend networking conference will feature leading ...
Breaking Medicine News(10 mins):Health News:RxNT Releases Enhanced ePrescribing iPhone App to Improve Prescriber Usability 2Health News:New Video from METTLER TOLEDO Shows the Advantages of Sample Handling Automation in Density Determination 2Health News:New Video from METTLER TOLEDO Shows the Advantages of Sample Handling Automation in Density Determination 3Health News:UPMC-University of Pittsburgh Named Center of Excellence for Rare Disorder 2Health News:UPMC-University of Pittsburgh Named Center of Excellence for Rare Disorder 3Health News:UPMC-University of Pittsburgh Named Center of Excellence for Rare Disorder 4Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 2Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 3Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 4Health News:The 2015 China Overseas Investment and Entrepreneurship Summit (COIES) Announced 2
... agency of potential trouble within 24 hours , TUESDAY, Sept. ... distribute food for people or animals to eat must now ... 24 hours, the U.S. Food and Drug Administration announced Tuesday. ... Registry, which was mandated by Congress two years ago in ...
... has awarded a consortium of Chicago-based institutions, led by ... establish a Developmental Center for AIDS Research, creating a ... and translational research in the prevention, detection and treatment ... is one of only two in the Midwest ...
... ... a Financing Mechanism to Immediately Begin Supporting NTD Programs in the Region; Marks First Financing ... ... Tropical Diseases announced today that it is partnering with the Inter-American Development Bank ...
... , LOS ANGELES, Sept. 8 ... the kitchen. Now you can serve up some of the same ... the new Terry Farrell Firefighters Fund California Firehouse Cookbook, you,ll get ... and their families. , , Created by the ...
... , Senators Bob Dole and ... discuss areas of bipartisan agreement in health reform , ... (BPC) and Better Health Care Together will host a bipartisan health ... labor leaders in the health reform debate. The event entitled, ...
... , WASHINGTON, Sept. 8 ... and Human Services (HHS), Office of the Inspector General (OIG) ... Program: Supplier Acquisition Costs and Services (OEI-04-07-00400) examining acquisition ... rehabilitation power wheelchairs available to Medicare beneficiaries. If readers incorrectly ...
Cached Medicine News:Health News:FDA to Require Faster Reporting of Food-Safety Problems 2Health News:NIH awards major grant to Chicago-based consortium to create center for AIDS research 2Health News:NIH awards major grant to Chicago-based consortium to create center for AIDS research 3Health News:Global Network for Neglected Tropical Diseases Partners with IDB, PAHO to Control and Eliminate Neglected Tropical Diseases in Latin America, Caribbean 2Health News:Favorite California Firehouse Recipes Fill New Cookbook 2Health News:Favorite California Firehouse Recipes Fill New Cookbook 3Health News:Favorite California Firehouse Recipes Fill New Cookbook 4Health News:Favorite California Firehouse Recipes Fill New Cookbook 5Health News:Favorite California Firehouse Recipes Fill New Cookbook 6Health News:Bipartisan Policy Center and Better Health Care Together to Host Joint Health Care Forum Tomorrow 2Health News:PMC Questions Methodology of OIG Report on Power Wheelchair Acquisition Costs 2
Bunell Mini-Modified Safety Finger Pin reduces PIP flexion contractures....
... Slings makes dynamic splinting easier and ... slings fit every splinting need. Non-slip ... on the distal phalanx. One size ... of 10 and 25. FoamWrap™ splints ...
... full PIP joint or DIP joint flexion ... arthritic changes. Unparalleled in comfort and softness, ... to prevent slipping and allows for infinite ... in packages of 5 and boxes of ...
... FoamWrap BuddyWraps hold the fingers safely ... need to use tape or prickly hook ... breathable, washable, and offers unparalleled comfort. Available ... length. The favorite choice of doctors and ...
Medicine Products: