Navigation Links
Dermatologists Caution That Severe Cases of Psoriasis Can Be Associated With Other Serious Medical Conditions

SAN FRANCISCO, March 5 /PRNewswire-USNewswire/ -- On the surface, the thick, red, scaly, itchy plaques of psoriasis -- which have been shown to have a significant negative impact on a person's overall quality of life -- may not appear to pose a serious health risk for patients. However, a growing body of research suggests that psoriasis patients are at an increased risk of developing serious medical conditions, including cardiovascular disease and diabetes, particularly when their psoriasis is severe.

Speaking today at the 67th Annual Meeting of the American Academy of Dermatology (Academy), dermatologist Joel M. Gelfand, MD, MSCE, FAAD, assistant professor of dermatology at the University of Pennsylvania School of Medicine in Philadelphia, spoke about this complex skin condition and its relationship to other serious medical conditions.

Dr. Gelfand explained that for the last two decades, research has shown that excessive inflammation is a critical feature of psoriasis. This discovery has led to innovative approaches to treating psoriasis, with therapies targeting selected areas of the immune system that are over-active in psoriasis patients. Excess inflammation also is present in other common conditions, such as hardening of the arteries, heart attacks, stroke, obesity and diabetes -- which may explain why some psoriasis patients may be at an increased risk for developing these other serious conditions.

Studies show the link between patients with severe psoriasis and diabetes, heart attack and coronary artery disease occurs independent of traditional risk factors for these other conditions -- such as obesity, smoking or high blood pressure.

Furthermore, Dr. Gelfand's recent research suggests that patients with severe psoriasis may have shorter life expectancies than non-psoriasis patients. Specifically, he found that those with severe psoriasis may die three to five years earlier than patients who do not have the disease.

"Patient education is critical in the early detection and management of these related conditions, many of which can be controlled with proper medical care," said Dr. Gelfand. To minimize the risk of developing associated medical conditions, Dr. Gelfand recommended that psoriasis patients lead a healthy lifestyle, avoid smoking, maintain an ideal body weight and get routine screenings for cardiovascular risk factors -- such as blood pressure and cholesterol checks.

"We need to educate psoriasis patients about the increased risk of cardiovascular disease so the prevention efforts can be instituted," explained Dr. Gelfand.

Experts in the dermatology and cardiology communities have issued consensus statements advocating that physicians educate patients with psoriasis -- particularly if the disease is severe -- about the potential association of psoriasis with other serious diseases, such as diabetes and cardiovascular disease.

Dr. Gelfand added that further research is needed to better determine how skin disease severity and activity affect the risk of developing these associated conditions and whether successful treatment of psoriasis alters the risks.

About Psoriasis

Psoriasis affects nearly 7 million Americans and can start at any age, although it most commonly starts in early adulthood (20s and 30s). Psoriasis has a genetic component, as approximately 40 percent of patients with psoriasis have a family history of the disease. While the exact cause of psoriasis is unknown, it is believed to occur due to an interaction of multiple genes, the immune system and the environment, according to Dr. Gelfand. The disease can be localized, affecting only the elbows or scalp, or can involve skin on the entire body.

To learn more about psoriasis, visit the PsoriasisNet section of, a Web site developed by dermatologists that provides patients with up-to-date information on the treatment and management of disorders of the skin, hair and nails.

Headquartered in Schaumburg, Ill., the American Academy of Dermatology (Academy), founded in 1938, is the largest, most influential, and most representative of all dermatologic associations. With a membership of more than 15,000 physicians worldwide, the Academy is committed to: advancing the diagnosis and medical, surgical and cosmetic treatment of the skin, hair and nails; advocating high standards in clinical practice, education, and research in dermatology; and supporting and enhancing patient care for a lifetime of healthier skin, hair and nails. For more information, contact the Academy at 1-888-462-DERM (3376) or

SOURCE American Academy of Dermatology
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. New Jersey American Water Lifts Precautionary Boil Water Advisory For Middlesex, Somerset and Union Counties
2. Post-Hoc Data Show Daily Activity Participation, Independence and Sleep Quality Improved in Adults with Moderate to Severe Rheumatoid Arthritis After Treatment with ORENCIA(R) (Abatacept)
3. Powerful New Efficacy Data in Moderate and Severe Hypertensive Patients Supports FDA Approval of AVALIDE(R) (Irbesartan-Hydrochlorothiazide) as the First Combination Therapy for Initial Use in Patients Likely to Need Multiple Drugs to Achieve Their Blood
4. LAP-BAND(R) System Weight-Loss Surgery Associated With More Than 70 Percent Reduced Risk of Death in People With Severe Obesity
5. Centocor and Janssen-Cilag Submit Applications Requesting Approval of Ustekinumab in the U.S. and Europe for Treatment of Moderate to Severe Plaque Psoriasis
6. Study Linking Increased Risk of Death to Severe Psoriasis a Call to Action
7. Abbotts HUMIRA(R) (adalimumab) Receives FDA Approval For Moderate to Severe Chronic Plaque Psoriasis
8. OPKO Health and Pathogenics Announce Data Publication Demonstrating the Potential Utility of NCT in a Severe Eye Infection
9. U.S. Food and Drug Administration Approves ORENCIA(R) (abatacept) for the Treatment of Moderate-to-Severe Polyarticular Juvenile Idiopathic Arthritis (JIA) in Patients Six Years and Older
10. Data Presented at the American Academy of Neurology Show XP13512/GSK1838262 Significantly Improved Symptoms of Moderate-to-Severe Primary Restless Legs Syndrome
11. Agennix Initiates A Randomized Double-Blind, Placebo-Controlled Phase 2 Study of Oral Talactoferrin in Severe Sepsis
Post Your Comments:
(Date:11/24/2015)... 2015  Thanks to a donor with a personal ... Center,s Sister Diane Grassilli Center for Women,s Health now ... San Francisco . Fred ... with a gift of $617,320 that allowed the Center ... Tomosynthesis and Whole Breast Ultrasound. Tomosynthesis, three-dimensional (3-D) mammography ...
(Date:11/24/2015)... Nov. 24, 2015 /PRNewswire/ - ESSA Pharma Inc. ("ESSA" ... announced today that the first patient has been enrolled ... a treatment for metastatic castration-resistant prostate cancer ("mCRPC"). ... --> the United States ... Phase 1/2 clinical trial, ESSA intends to demonstrate the ...
(Date:11/24/2015)... PUNE, India , November 24, 2015 ... new market research report "Spine Biologics Market by Product Type ... Type (Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion), ... by MarketsandMarkets, the global market was valued at $1.90 Billion ... 2020, at a CAGR of 4.4% during the forecast period ...
Breaking Medicine Technology:
(Date:11/25/2015)... ... ... In an ongoing Clinical Study conducted by an independent physician, Andrew Gostine, ... evaluating the efficacy of its product and its disinfection protocol. This study is taking ... 2014 through October 2015 at a 360-bed, acute-care, academic medical center located in Chicago, ...
(Date:11/25/2015)... ... November 25, 2015 , ... In ... nation’s Periwinkle Pioneers, individuals and groups responsible for advancing care for pulmonary hypertension ... Pioneers, nominated by the public, will receive special recognition throughout 2016 as part ...
(Date:11/25/2015)... ... 25, 2015 , ... Many people know of the common symptoms of low ... dry skin. But many people who find their cholesterol levels and weight are creeping ... thyroid, especially if they don’t have any of the other symptoms. , Thyroid hormone ...
(Date:11/25/2015)... ... November 25, 2015 , ... Bunion ... in an early celebration of the early holiday shopping season. Starting Wednesday November ... (normally $33.95 ea). Black Friday promotional pricing is in addition to any automatic ...
(Date:11/24/2015)... ... ... New patients who wish to seek treatment for missing teeth can now ... Mississauga, ON practice. Dr. Williams has been providing dental service for over 34 years, ... teeth can lead to a variety of complications if they are not replaced quickly, ...
Breaking Medicine News(10 mins):