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Dermagen Reports Successful Phase I/IIa Clinical Trial for Atopic Dermatitis
Date:12/2/2009

sition as it explores additional, first-in-class opportunities for the candidate drug and other compounds for the topical treatment of dermatological infections, such as impetigo and infected wounds and burns."

The rapid resistance development by microbes limits the use of classical antibiotics for indications such as atopic dermatitis, especially for topical applications. DermaGen's AMP is derived from natural endogenous human proteins and there is low probability that it will induce resistance as it lack a specific molecular target on bacteria and other microbes. Anti-infective treatments represent the most important component of the global dermatology market, accounting for 31% of total market value, approximately USD 4 billion.

Conny Bogentoft, CEO of Karolinska Development, said, "Pergamum and its Operating Units form an important part of the Karolinska Development portfolio. They represent a strong offering in dermatology and wound healing markets with products targeting indications with significant unmet medical needs. It is encouraging to see the progress they are making in their clinical development programs."

About DermaGen

DermaGen AB is a specialty pharmaceutical company and world leader in the research and development of endogenous antimicrobial peptides. Founded in 2004, DermaGen focuses on the development of topically applied products for the prevention and treatment of bacterial and fungal skin infections. Novel antimicrobial peptides are modified to increase their potency and stability, facilitating the development of pharmaceutical products that fulfill unmet medical needs and significantly improve quality of life for patients. DermaGen partners with leading international pharmaceutical companies in the dermatological field to ensure rapid and cost-efficient development. The company is based in Lund, Sweden and is part of the Pergamum group of companies.

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SOURCE DermaGen AB
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