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Dendreon Reports PROVENGE Regulatory and Commercialization Progress and Future Pipeline Plans at Analyst Event
Date:9/24/2009

first half of 2011.
  • Dendreon recently signed leases for additional manufacturing facilities in Los Angeles and Atlanta. Both are expected to have 36 workstations, and additional capacity from these facilities will be available in the second half of 2011.
  • Dendreon will leverage established third parties for patient/physician scheduling, apheresis and product transportation. Dendreon's primary provider for apheresis services will be the American Red Cross, which has a nationwide network of apheresis centers. This resource will be augmented with other regional apheresis centers. There are more than 600 apheresis centers in the U.S., and Dendreon expects to contract with 150 to 200 of them at peak demand.
  • The Company has developed and will implement Intellivenge(TM), a first-of-its-kind advanced logistical and patient treatment management and planning system, which coordinates the patient and physician scheduling as well as the operational and logistic activities should PROVENGE be approved by the FDA. With Intellivenge, physicians and patients can log-in and track where their product is throughout the manufacturing process.
  • Dendreon's headcount is currently 290 and is expected to more than double by the anticipated time of product launch.

    • Product Pipeline

    • Dendreon plans to initiate a clinical trial of NEUVENGE(TM) (lapuleucel-T), its active cellular immunotherapy (ACI) targeting the Her2-Neu pathway in bladder cancer in late 2010 or early 2011. NEUVENGE may have applicability to multiple types of cancer including bladder, breast and colorectal cancers.
    • CA9 (carbonic anhydrase IX), which is expressed in multiple types of cancerous tissues, is being used to develop an ACI which is expected to enter Phase 1 clinical trials for metastatic renal cell carcinoma in 2011.
    • CEA (carcinoembryonic antigen) is expressed i
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    SOURCE Dendreon Corporation
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