Navigation Links
Delcath Expands Phase III Trial for Metastatic Melanoma to Include St. Luke's Cancer Center
Date:6/3/2008

resident and CEO of Delcath Systems. "We plan to continue expanding this trial to centers throughout the United States and broadening the availability of the technology."

The Phase III Study

The Phase III study is designed to test Delcath's proprietary PHP System for the regional delivery of melphalan to the liver to treat patients with metastatic ocular and cutaneous melanoma who have unresectable tumors in the liver. The Delcath PHP System is designed to deliver significantly higher doses of anti-cancer drugs to a patient's liver while preventing entry of the drugs to the rest of the patient's circulation. This isolation limits toxicities that result from systemic chemotherapy treatments.

Patients in the Phase III trial initially are randomized into one of two treatment arms, including immediate treatment with melphalan via the Delcath PHP System or treatment with best alternative care. The study is designed to evaluate the duration of tumor response in each of the two study arms. Following guidelines established by U.S. Food and Drug Administration (FDA) under a Special Protocol Assessment (SPA), when disease progresses in patients enrolled in the best alternative care arm of the trial, they are permitted to "cross over" and receive treatment with the Delcath PHP System. The Phase III study, which recently exceeded 33% enrollment, is expected to be completed in 2009, leading to an application to the US Food and Drug Administration (FDA) for commercial approval of the Delcath PHP System.

About Delcath Systems, Inc.

Delcath Systems is a developmental stage company testing its percutaneous perfusion technology for the isolated delivery of high doses of therapeutic and chemotherapeutic agents. The Delcath PHP System is currently being tested with the drug melphalan in Phase III and Phase II clinical trials. The Company's intellectual property portfolio currently consists of twenty-eight patents on a worldwide basis including the U.S
'/>"/>

SOURCE Delcath Systems, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Delcath Updates Phase III Patient Enrollment as Pivotal Trial Accelerates, Durable Tumor Responses In Phase II Study Also Cited
2. Delcath Expands Phase III Trial for Metastatic Melanoma to Include University of Maryland Medical Center
3. BiPar Sciences Expands Clinical Development of BSI-201, A Novel PARP Inhibitor, With Phase 2 Trial in Uterine Cancer
4. BiPar Sciences Expands Phase 2 Clinical Trials of BSI-201, a Novel DNA Repair Inhibitor, in Ovarian Cancer
5. CoreSpine Technologies Expands Spinal Disc Site Preparation Efforts
6. Alseres Pharmaceuticals Expands Sites for the First Stage of the ALTROPANE(R) Phase III Clinical Trial Program
7. Senesco Expands on Recently Announced Preclinical Pancreatic Islet Data
8. BiPar Sciences Expands Clinical Program for BSI-201, a Novel DNA Repair Inhibitor, in Brain Cancer
9. PAREXEL Expands Global Clinical Pharmacology Capabilities
10. Millennium Expands VELCADE(R) (Bortezomib) For Injection Program In Non-Hodgkins Lymphoma
11. PAREXEL Expands Late Phase Clinical Research Services and Appoints Leading Pharmacoepidemiology Expert Victor Kiri
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... HARRISBURG, Pa. , Dec. 19, 2014 ... a routine checkup and cleaning when he or she ... term you,ve probably heard before, you may have several ... You,ll be relieved to know it,s nothing to ... help answer patients, questions and alleviate any anxiety the ...
(Date:12/19/2014)... HILL, N.C. , Dec. 19, 2014 /PRNewswire/ ... to optimize a product,s web presence to reflect ... Brand websites, in particular, must meet the needs ... regulations and culture. According to ... more than half of the participating companies averaged ...
(Date:12/19/2014)... Texas , December 18, 2014 ... networked software application/module that is used to store, ... images. RIS comprises a patient tracking and scheduling ... The integration of RIS with HIS and other ... for patient registration and patient scheduling, patient list ...
Breaking Medicine Technology:Root Canals Have Become More Routine 2Building a Best-in-Class Pharma Global Brand Website 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 3
... Inc. today announced that Ho Cho, Ph.D., the company,s ... company,s antibody drug conjugate (ADC) programs at five upcoming ... recent xenograft studies comparing Ambrx ADCs with those created ... been clinically validated as safe and efficacious for creating ...
... YORK, June 22, 2011 (Digital Experience!) -- iHealth ... personal healthcare products including the iHealth BP3 Blood Pressure ... announced that multiple national retail chains will now distribute ... Pressure Monitoring System is now available in all Apple ...
Cached Medicine Technology:Ambrx to Present Data from Antibody Drug Conjugate Program at Upcoming Scientific Conferences 2iHealth Lab's Blood Pressure Self-Monitoring System Gets Nationwide Distribution 2
(Date:12/20/2014)... Twin Cities DI Day is recognized as the premier ... financial professionals come together each year to hear up ... to protect their clients and to be inspired by ... of disability. , On September 23rd, 2014, financial professionals ... The 13th Annual Twin Cities DI Day where they ...
(Date:12/19/2014)... 2014 Sweetdressy.com , a leading ... its newest selection of cheap prom dresses for ladies ... in the world and clients can buy these dresses ... prom dresses feature cool cuts and delicate craftsmanship, and ... the middle-end market. Discount shipping costs are available for ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 SuperCloset raises ... SuperClone Rooms. SuperCloset continues to offer indoor growers the ... one of the new SuperClone Rooms with the award ... and turnkey indoor hydroponic grow room setup. , The ... world, SuperCloset’s SuperPonic SuperCloner 50 . ...
(Date:12/19/2014)... 2014 The print component of Vision ... subscription of the Toronto Star, with a circulation of ... The digital component is distributed nationally through a vast ... news sites and partner outlets. To explore the digital ... The publication features an exclusive interview with Mark ...
(Date:12/19/2014)... FRIDAY, Dec. 19, 2014 (HealthDay News) -- Injectable drug ... double the suicide attempt rate of other substance users, ... use is associated with the risk of suicide attempt ... the University of Montreal, said in a university news ... users. We wanted to know who among substance users ...
Breaking Medicine News(10 mins):Health News:The 13th Annual Twin Cities DI Day Now On Video 2Health News:The 13th Annual Twin Cities DI Day Now On Video 3Health News:Cheap Prom Dresses Online Now at Sweetdressy.com 2Health News:SuperCloset Continues to Innovate with New Complete Indoor Grow Room Packages, The SuperClone Rooms are the Newest Addition to the Award Winning SuperRoom Lineup 2Health News:Mark DeMontis, Founder of Courage Canada, shares his passion for bringing hockey to those affected by blindness in Mediaplanet’s “Vision and Hearing” campaign 2Health News:Cocaine, Amphetamines May Up Injection Drug Users' Suicide Risk 2
... in the supercomputer MareNostrum at the Barcelona Supercomputing Center, ... Research in Biomedicine (IRB Barcelona) have presented the world,s ... new database holds more than 1,700 proteins and is ... been developed to study the basic biology of proteins ...
... brain structure known as the amygdala. It is the amygdala ... and not only triggers palpitations or nausea but can also ... been known about the function of this part of the ... develops, and which of the countless neurons in the amygdaloid ...
... News) -- Middle-aged couples with good "numeracy" skills are wealthier ... Numeracy -- the ability to reason with numbers and ... learned in school, according to the RAND Corporation researchers who ... the U.S. Health and Retirement Survey. The investigators found ...
... WEDNESDAY, Nov. 10 (HealthDay News) -- Offering your baby ... protection against the development of the antibodies associated with type ... disease, new research suggests. When Finnish researchers randomly ... to receive either a regular infant formula, or one that ...
... prostate cancer may have an increased risk of colorectal ... in The Journal of the National Cancer Institute. ... treatment in men with prostate cancer, although its usage ... effects, including osteoporosis, cardiovascular disease, diabetes and obesity; the ...
... the American Society of Nephrology (ASN) proudly highlight ... by The Halpin Foundation-ASN Research Grant, created to ... award provides recipients transition funding toward successful application ... PhD (McGill University Faculty of Medicine), the 2008 ...
Cached Medicine News:Health News:Scientists at IRB Barcelona and BSC publish the world's largest video data bank of proteins 2Health News:Circuitry of fear identified 2Health News:Math Skills Boost Couples' Financial Worth: Study 2Health News:Special Infant Formula Might Help Shield Babies from Type 1 Diabetes 2Health News:Special Infant Formula Might Help Shield Babies from Type 1 Diabetes 3Health News:Special Infant Formula Might Help Shield Babies from Type 1 Diabetes 4Health News:Colorectal cancer risk increases in prostate cancer patients on androgen deprivation therapy 2Health News:Putting the spotlight on membranous nephropathy 2
... Rotanta 460 family of ... line that meets a ... They feature high capacity, ... state-of-the-art technology and high ...
... Five models to choose fromTabletops ... refrigeration. Features of the Spinchron DLX ... Smooth, maintenancefree operation with a brushless ... acceleration and deceleration rates; Continuous or ...
The Spinchron 15 centrifuge provides all the versatility and high capacity needed for today's full-service clinical lab needs. This centrifuge is available in a nonrefrigerated model with a speed up ...
... CKX microscopes utilize the infinity-corrected ... and operability in cell checking. ... inverted microscope suited to routine ... fields--from tissue culture and embryology ...
Medicine Products: