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DelMar Pharmaceuticals Presents Data Supporting VAL-083 as a Potential Treatment for Three Chemotherapy Resistant Cancers
Date:10/21/2013

VANCOUVER, British Columbia and MENLO PARK, Calif., Oct. 21, 2013 /PRNewswire/ -- DelMar Pharmaceuticals, Inc. (OTCQB: DMPI) ("DelMar" and "DelMar Pharma") today announced the presentation of data at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics Annual Meeting. The data presented today, along with historical research by the U.S. National Cancer Institute (NCI), support the utility of VAL-083 as a potential new treatment for three chemotherapy resistant cancers: glioblastoma (GBM), chronic myelogenous leukemia (CML) and non-small cell lung cancer (NSCLC).

"Chemotherapy resistance continues to be a major therapeutic hurdle in treating cancers," said Jeffrey Bacha, president and CEO of DelMar Pharma.  "In our studies and numerous clinical studies by the National Cancer Institute, VAL-083 has shown therapeutic safety and efficacy in treating a broad range of cancers. The data we presented today show that the VAL-083's unique mechanism of action could be an important new therapeutic to treat glioblastoma, chronic myelogenous leukemia and non-small cell lung cancer, where chemotherapy resistance remains a significant unmet clinical need."

DelMar Pharma's lead drug candidate, VAL-083, benefits from historical development activities at the NCI, where VAL-083's unique mechanism and safety in patients was well studied. Published historical and DelMar's new pre-clinical and clinical data demonstrate that VAL-083 is active against a range of tumor types and is well tolerated. 

Mr. Bacha continued, "Building upon an existing database of more than 1,000 patients in the U.S. and more than 40 Phase I and II NCI-sponsored human clinical trials, we have seen deep insights into VAL-083 safety and efficacy, which will help us streamline development and commercialization in orphan ca
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SOURCE DelMar Pharmaceuticals, Inc.
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