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DelMar Pharmaceuticals Announces Change of Fiscal Year End and Provides Update on Glioblastoma Clinical Trial
Date:7/24/2014

d Mr. Bacha.

Clinical Trial Update

Our lead drug candidate, VAL-083, is currently undergoing a Phase I/II clinical trial in the United States as a potential new therapy for the treatment of refractory glioblastoma multiforme (GBM), the most common and aggressive form of brain cancer. 

We most recently provided an update at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) where it was disclosed that VAL-083 was safe and well tolerated at doses up to 30mg/m2 and that the next cohort (40mg/m2) had been opened for enrollment. DelMar's ASCO data presentation can be viewed on our website at: http://www.delmarpharma.com/products/publications/.

We are now pleased to confirm that the 40mg/m2 cohort is fully enrolled and, subject to completion of a safety review period, we plan to move forward with amending the protocol to allow us to treat patients at higher dosing levels. 

"To date, we have not seen evidence of a dose limiting toxicity in the initial patients at the 40mg/m2 dose. We believe it is prudent to pursue higher dosing levels with the goal of obtaining the maximum the level of drug that can be safely delivered to patients. This will enhance our likelihood of success in achieving our goal to commercialize VAL-083 as a new medicine for the treatment of refractory GBM patients who currently have no available therapeutic options."

About DelMar Pharmaceuticals

DelMar Pharmaceuticals was founded in 2010 to develop and commercialize proven cancer therapies in new orphan drug indications where patients are failing modern targeted or biologic treatments. The Company's lead asset, VAL-083, is currently undergoing clinical trials in the United States as a potential treatment for recurrent glioblastoma multiforme (GBM), the most common and aggressive form of brain can
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SOURCE DelMar Pharmaceuticals, Inc.
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