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DelMar Pharma Presents Encouraging Data From Ongoing Phase I/II GBM Clinical Trial With VAL-083
Date:4/10/2013

VANCOUVER, British Columbia and MENLO PARK, Calif., April 10, 2013 /PRNewswire/ -- DelMar Pharmaceuticals, Inc. (OTCQB: DMPI) today announced additional positive interim data from an ongoing Phase I/II clinical trial of VAL-083 in patients with recurrent glioblastoma multiforme (GBM) or progressive secondary brain tumor. 

The data are being presented at the American Association for Cancer Research (AACR) Annual Meeting in Washington, D.C. during a clinical poster session entitled, "A Phase I/II Study of VAL-083 in Patients with Recurrent Malignant Glioma or Progressive Secondary Brain Tumor." Information regarding the presentation: Session Title:Phase II and Phase III Adult Clinical TrialsSession Time:Wednesday, April 10, 2013, 8:00 am – 12:00 pmPresentation:4672Poster Title:"A Phase I/II Study of VAL-083 in Patients with Recurrent Malignant Glioma or Progressive Secondary Brain Tumor"Location:Hall A-C, Poster Section 2, Washington Convention Center"These data represent continued progress to modernize the dosing regimen with VAL-083 as a potential treatment for recurrent brain tumors, including GBM, the most common and aggressive form of brain cancer.  We are optimistic that we will continue to gather positive data as we reach higher doses in our clinical trial," said Jeffrey Bacha , President and Chief Executive Officer of DelMar Pharmaceuticals.

The data presented are part of an ongoing Phase I/II open-label, single arm dose-escalation study. Three dose cohorts were completed without reaching dose-limiting toxicity (DLT), and no drug-related adverse effects were detected. VAL-083 was seen to be safe and well tolerated at tested doses in patients who have failed other available therapies. In particular, GBM patients in the trial must have failed both bevacizumab (Avastin®) and temozolomide (Temodar
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SOURCE DelMar Pharmaceuticals, Inc.
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