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De nouvelles directives recommandent la fidaxomicine pour tous les patients pouvant suivre un traitement antibiotique par voie orale pour une infection à Clostridium difficile
Date:10/29/2013

r encore plus les politiques nationales de traitement de l'ICD dans les hôpitaux européens. Pour la rédaction de ces nouvelles directives, l'ESCMID et une équipe d'experts issus de 11 pays européens ont lancé une recherche informatique des publications afin de passer en revue les essais randomisés et non randomisés étudiant les effets d'une intervention sur le résultat clinique d'une ICD. Les directives 2013 mises à jour fournissent une vue d'ensemble des options de traitement de l'ICD actuellement disponibles ainsi que des recommandations basées sur des preuves sur le traitement de l'ICD.[3]

Une copie complète des directives 2013 mises à jour et leurs recommandations sont disponibles en consultant : http://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12418/abstract

REMARQUES À L'INTENTION DES ÉDITEURS

À propos de l'ICD

L'IDC est une grave maladie causée par l'infection de la paroi interne du côlon par la bactérie C. difficile. Cette bactérie produit des toxines qui entraînent une inflammation du côlon, des diarrhées et, dans certains cas, la mort.[20] Les patients développent généralement une IDC après avoir utilisé des antibiotiques à large spectre qui perturbent la flore gastro-intestinale normale, et permettent à la bactérie C. difficile de se développer.[20],[21] L'ICD a un impact énorme sur les systèmes de santé et les patients infectés sont parfois obligés de prolonger leur séjour en hôpital de 1 à 3 semaines[22],[23],[24] pour un coût supplémentaire pouvant atteindre 14 000 € comparé aux patients sans ICD.[25]

À propos de la mise à jou
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SOURCE Astellas Pharma Europe Ltd
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