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Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden
Date:9/2/2014

ch wirksamen Präventionstherapien, stellt der VF-bedingte Schlaganfall weiterhin eine große und zunehmende Belastung für die Klinik und Gesellschaft dar.

"Die aktuellsten Daten von GARFIELD-AF belegen, dass die Einführung innovativer Therapien zu einer veränderten Behandlung von VF-Patienten im Bereich Schlaganfallprävention geführt hat," erklärte Professor Lord Ajay Kakkar, Professor of Surgery beim University College London und Director des TRI. "Vorangegangene Studien haben bewiesen, dass die Patientenergebnisse durch die ordnungsgemäße Anwendung der Antikoagulanzientherapie verbessert werden können. Die Beobachtungen in der klinischen Praxis laut GARFIELD-AF legen jedoch nahe, dass weiterhin viel getan werden muss, um sicherzustellen, dass die wissenschaftlich begründeten Leitlinien umgesetzt werden, einschließlich der Auswahl von geeigneten Patienten für die Antikoagulanzientherapie und ihre optimale Behandlung."

Bei dem Satelliten-Symposium des ESC-Kongresses 2014 wurden die vorläufigen Behandlungsdaten für 31.666 GARFIELD-AF-Patienten in 34 Ländern während der ersten drei von fünf geplanten Kohorten präsentiert. [2] Seit dem Start von GARFIELD-AF im Jahr 2009 hat die Zulassung von NOAK einschließlich Faktor-Xa-Inhibitoren (Rivaroxaban, Apixaban) und einem direkten Thrombininhibitor (Dabigatran) die Verordnungsgewohnheiten verändert, da eine Alternative zu Vitamin-K-Antagonisten (VKA), dem Therapiestandard, verfügbar war. Der Anteil von VK-Patienten, der eine NOAK erhielt, stieg während der 1. Kohorte (Dezember 2009 bis Oktober 2011) von 3,1 % auf 26,4 % während der 3. Kohorte (Juni 2013 bis Juni 2014). Allerdings stieg im gleichen Zeitraum der Anteil von Patienten mit einem beliebigen Antikoagulans lediglich von 60,6 % auf 67,5 %, da weniger Patienten einen VKA er
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SOURCE GARFIELD-AF
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