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Data on DermTech's Non-invasive Test for Melanoma Are Published in the British Journal of Dermatology
Date:2/7/2011

LA JOLLA, Calif., Feb. 7, 2011 /PRNewswire/ -- DermTech International, Inc., a biotechnology company dedicated to bringing genomic medicine to dermatologists, today announced that the discovery data on its new genomic assay for melanoma have been published in the British Journal of Dermatology.  The test is based on the EGIR™ technology (Epidermal Genetic Information Retrieval) that non-invasively collects cells from the skin's surface using a custom adhesive.  Details from the paper titled "Non-invasive Genomic Detection of Melanoma" show that the test is 100% sensitive in identifying melanoma.  

The EGIR-based technology assessed pigmented skin lesions thought to be suspicious for melanoma and identified all the lesions containing either in situ (early stage) or invasive disease correctly 100% of the time.  The test registers 88% specificity (12% false positives).  These results are more accurate than any currently available melanoma detection tool.  The study was performed at 18 sites across the United States.

"Once it becomes available, this new 'tape stripping' technology will allow us to non-invasively evaluate lesions which might not rise to the level of clinical suspicion that would prompt one to perform a biopsy, but which nonetheless, might harbor melanoma," said Mitchell Kline, MD, Clinical Assistant Professor of Dermatology, New York Presbyterian-Weill Cornell Medical School.  "I believe that this genomic-based approach will allow dermatologists to more fully assess patients in advance of a biopsy and the test's very low false positive rate should translate to a reduced number of required excisions.  This is a technology I expect will have advantages for patients and the healthcare system."

The paper shows that the EGIR method, which uses adhesive to harvest cells from the skin, identified genes that were differentially expressed in melanomas versus normal skin and nev
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SOURCE DermTech International, Inc.
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