Navigation Links
Data Presented at ACR Meeting Demonstrate Safety of Colcrys® (Colchicine, USP) for Treatment of Gout Flares in Patients with Multiple Co-Morbid Conditions
Date:11/8/2010

ATLANTA, Nov. 8, 2010 /PRNewswire/ -- Patients who experience gout flares can be treated safely with Colcrys® (colchicine, USP), even in the presence of co-morbid conditions that often present physicians with treatment challenges, according to a new analysis presented here at the 74th Annual Scientific Meeting of the American College of Rheumatology (ACR).

"Many patients with gout have other serious health conditions to consider, including cardiovascular and metabolic disorders, hypertension and kidney disease, which can make gout treatment complex," said Matthew W. Davis, M.D., R.Ph., Chief Medical Officer, URL Pharma. "This analysis demonstrates that patients with these comorbidities did not have an increased likelihood of adverse events from the use of Colcrys."

Data were collected as part of a post-hoc analysis of The Acute Gout Flare Receiving Colchicine Evaluation (AGREE) trial, a pivotal Phase 3 study of Colcrys in the treatment of gout flares. AGREE results were presented at the 2009 ACR annual meeting, and were published in Arthritis & Rheumatism in March 2010.

Colcrys is the only single-ingredient colchicine product approved by the U.S. Food and Drug Administration (FDA) for the prevention and treatment of gout flares, and for the treatment of Familial Mediterranean Fever (FMF).

Study Design

This Phase 3, randomized, double-blind, placebo-controlled parallel group study represents a regression analysis of the previously presented AGREE trial. A total of 185 patients meeting ACR criteria for acute gout flares were randomized to receive, within 12 hours of symptom onset, either high-dose colchicine (1.2 mg, then 0.6 mg hourly x 6 hours = 4.8 mg total); Colcrys (1.2 mg, then 0.6 mg in 1 hour = 1.8 mg total, followed by 5 placebo doses hourly); or placebo (2 capsules, then 1 capsule hourly x 6 hours).  

Logistics regression was undertaken using presence or absence of adverse events (AEs
'/>"/>

SOURCE URL Pharma, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
2. Pre-clinical Data on Recent Advances with HIV VLP Vaccine Presented at AIDS Vaccine 07 Conference
3. New Study Presented at WorldSleep 2007 Demonstrates Ramelteon Has Sustained Efficacy Over Six Months in Adults With Chronic Insomnia
4. Genasense(R) Data in Melanoma to be Presented in Opening Session at First Worldwide Melanoma Center Meeting of the European Association of Dermato-Oncology
5. Ozarelix Phase 2 Data Presented at 29th Congress of the Societe Internationale dUrologie
6. GeoVax Successful HIV/AIDS Vaccine Trial Data Presented at AIDS Vaccine 2007 Conference
7. Study Results for Aclidinium Bromide, a Novel Anticholinergic, Presented at European Respiratory Society Annual Congress
8. Promising Data from Paratek Pharmaceuticals MAR Inhibitor Program Presented in Late Breaker Session at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
9. New Phase III Data Presented for Once Monthly Dosing Regimen of Risedronate to Treat Postmenopausal Osteoporosis
10. Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
11. Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... According to a new market research report " ... Transcranial Magnetic Stimulation), Application (Depression, Parkinson,s, Tinnitus, Alzheimer,s, Epilepsy, Ischemia, ... the global Neuromodulation Market is estimated at $3.65 Billion in ... at a CAGR of 11.2% during the forecast period. ... market data T ables and 32 ...
(Date:7/2/2015)... 25, 2015 Research and Markets( http://www.researchandmarkets.com/research/nlfg34/cancer ... by Technology, Imaging and by Application - Forecast to 2020" ... is expected to reach $13.1 Billion in 2020 from an estimated ... The market is dominated by North America ... , and Rest of the World (RoW). The cancer diagnostics ...
(Date:7/2/2015)... FRANCISCO , July 2, 2015  The Green ... ), the world,s first HIPAA compliant mobile app that ... of farm-to-table fresh medical marijuana, announced today that their ... Unlike Eaze, Meadow and more than half a ... the last year, Loud Cannabis is unique in that ...
Breaking Medicine Technology:Neuromodulation Market Worth $6.20 Billion by 2020 2Neuromodulation Market Worth $6.20 Billion by 2020 3Neuromodulation Market Worth $6.20 Billion by 2020 4Global Cancer Diagnostics Market Report 2015 - Technology, Imaging and by Applications Forecasts to 2020 for the $13 Billion Industry 2New Cannabis Delivery App Gets Product to Patient in Under 7 Minutes 2
(Date:7/3/2015)... ... ... Harvest Hope Food Bank will hopefully be getting a large donation of canned food ... of Greenville SC are making it their mission to collect as many canned items as ... donations from the public as well. As part of the canned food drive, these local ...
(Date:7/3/2015)... ... 2015 , ... Scientists at several top US cancer centers believe they now ... Click here to read the complete story , just posted on the Surviving ... Medical Center, and New York University exposed mice with a mutation on the tumor ...
(Date:7/3/2015)... NY (PRWEB) , ... July 03, 2015 , ... ... Learning Lecture took place on June 25, 2015 at 1:00pm. The Association welcomed ... explored issues pertaining to injured bicyclists and practical points of investigating these types ...
(Date:7/3/2015)... ... July 03, 2015 , ... First Choice Emergency Room , the largest ... MD as the new Medical Director of its Frisco facility. , “We are pleased ... facility,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. ...
(Date:7/3/2015)... ... ... The Celebrity Dresses is currently running a promotion through July 30th. Anyone ... the opportunity to get 10% discount on orders that are over $100. , The ... use coupon codes or remember redemption codes. , There is a low price ...
Breaking Medicine News(10 mins):Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 2Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 3Health News:Study Finds Small Amounts of Asbestos May Trigger Mesothelioma in People with Genetic Mutation, According to Surviving Mesothelioma 2Health News:Attorney from William Mattar Leads Discussion on Bicycle Accidents 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 3Health News:Celebrity Fashion Summer Party Dresses on sale at TheCelebrityDresses.com 2
... House of the Lifestyle Center of America are offering The Diabetes ... all-expenses-paid, year-long treatment plan, focusing on the root causes of the ... ... New York, NY (PRWEB) June 30, 2008 -- This week ...
... 2008 The emergence of methicillin-resistant Staphylococcus aureus ... more complications and longer hospital stays for children ... researchers report. , Acute osteomyelitis, a bone ... caused by the staph bacteria. Treatment has traditionally ...
... EDITION (p. 26). In this second annual,double issue, Newsweek ... from whether politicians should pander, whether having,children makes you ... of global warming. Readers can also test their Global ... the issue. Try these:, 1. How many presidents ...
... Homosexual behaviour is largely shaped by genetics and ... world,s largest study of twins. , Writing in ... , researchers from Queen Mary,s School of Biological ... report that genetics and environmental factors (which are ...
... OptiNose announced today that it presented important new data ... delivery device with sumatriptan for the treatment of migraines. ... combination achieves migraine relief as quickly and efficiently as ... injuries. OptiNose presented the data at the Annual ...
... (PTCB), the leading national program that has ... and congratulates the Florida House of Representatives ... requiring new standards for pharmacy technicians. The ... toward increasing patient safety for consumers. The ...
Cached Medicine News:Health News:The Diabetes Challenge: Blogging Away Diabetes 2Health News:More severe bone infections, health complications in children linked to MRSA, researchers find 2Health News:More severe bone infections, health complications in children linked to MRSA, researchers find 3Health News:NEWSWEEK: Media Lead Sheet - July 7-14, 2008 Double Issue (On Newsstands Monday, June 30) 2Health News:NEWSWEEK: Media Lead Sheet - July 7-14, 2008 Double Issue (On Newsstands Monday, June 30) 3Health News:NEWSWEEK: Media Lead Sheet - July 7-14, 2008 Double Issue (On Newsstands Monday, June 30) 4Health News:NEWSWEEK: Media Lead Sheet - July 7-14, 2008 Double Issue (On Newsstands Monday, June 30) 5Health News:Homosexual behavior due to genetics and environmental factors 2Health News:OptiNose presents data on highly effective migraine treatment 2Health News:Pharmacy Technician Certification Board (PTCB) Supports Florida's New Patient Safety Solution 2Health News:Pharmacy Technician Certification Board (PTCB) Supports Florida's New Patient Safety Solution 3
1L...
... Series 2000 Pipette is a synonym for ... and robust design, and superior operating comfort. ... operate the measuring stroke and blow-out as ... "pipette/tip" system ensures utmost accuracy and precision. ...
2L...
... is ideal for repeated pipetting ... volume FInnpipettes offer the same ... Finnpipette Digital pipettes: New, ... Soft-touch tip ejection, Safety label, ...
Medicine Products: