Navigation Links
Data Presented at ACR Meeting Demonstrate Safety of Colcrys® (Colchicine, USP) for Treatment of Gout Flares in Patients with Multiple Co-Morbid Conditions
Date:11/8/2010

ATLANTA, Nov. 8, 2010 /PRNewswire/ -- Patients who experience gout flares can be treated safely with Colcrys® (colchicine, USP), even in the presence of co-morbid conditions that often present physicians with treatment challenges, according to a new analysis presented here at the 74th Annual Scientific Meeting of the American College of Rheumatology (ACR).

"Many patients with gout have other serious health conditions to consider, including cardiovascular and metabolic disorders, hypertension and kidney disease, which can make gout treatment complex," said Matthew W. Davis, M.D., R.Ph., Chief Medical Officer, URL Pharma. "This analysis demonstrates that patients with these comorbidities did not have an increased likelihood of adverse events from the use of Colcrys."

Data were collected as part of a post-hoc analysis of The Acute Gout Flare Receiving Colchicine Evaluation (AGREE) trial, a pivotal Phase 3 study of Colcrys in the treatment of gout flares. AGREE results were presented at the 2009 ACR annual meeting, and were published in Arthritis & Rheumatism in March 2010.

Colcrys is the only single-ingredient colchicine product approved by the U.S. Food and Drug Administration (FDA) for the prevention and treatment of gout flares, and for the treatment of Familial Mediterranean Fever (FMF).

Study Design

This Phase 3, randomized, double-blind, placebo-controlled parallel group study represents a regression analysis of the previously presented AGREE trial. A total of 185 patients meeting ACR criteria for acute gout flares were randomized to receive, within 12 hours of symptom onset, either high-dose colchicine (1.2 mg, then 0.6 mg hourly x 6 hours = 4.8 mg total); Colcrys (1.2 mg, then 0.6 mg in 1 hour = 1.8 mg total, followed by 5 placebo doses hourly); or placebo (2 capsules, then 1 capsule hourly x 6 hours).  

Logistics regression was undertaken using presence or absence of adverse events (AEs
'/>"/>

SOURCE URL Pharma, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
2. Pre-clinical Data on Recent Advances with HIV VLP Vaccine Presented at AIDS Vaccine 07 Conference
3. New Study Presented at WorldSleep 2007 Demonstrates Ramelteon Has Sustained Efficacy Over Six Months in Adults With Chronic Insomnia
4. Genasense(R) Data in Melanoma to be Presented in Opening Session at First Worldwide Melanoma Center Meeting of the European Association of Dermato-Oncology
5. Ozarelix Phase 2 Data Presented at 29th Congress of the Societe Internationale dUrologie
6. GeoVax Successful HIV/AIDS Vaccine Trial Data Presented at AIDS Vaccine 2007 Conference
7. Study Results for Aclidinium Bromide, a Novel Anticholinergic, Presented at European Respiratory Society Annual Congress
8. Promising Data from Paratek Pharmaceuticals MAR Inhibitor Program Presented in Late Breaker Session at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
9. New Phase III Data Presented for Once Monthly Dosing Regimen of Risedronate to Treat Postmenopausal Osteoporosis
10. Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
11. Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... YORK and LONDON , ... global orthopedic industry are expected to grow at an ... in terms of value and volume. Hip, knee and ... developed world while in emerging economies they have a ... rates are challenging the use of composites. Non-metallic orthopedic ...
(Date:12/24/2014)... ResMed (NYSE: RMD ) today announced ... medical device manufacturer BMC Medical Co., Ltd. ... listed below infringe ResMed,s patents, and entered an order prohibiting ... the United States : , iVolve ... Willow nasal pillows mask , iVolve full face mask ...
(Date:12/24/2014)... DALLAS , Dec. 23, 2014  Lockton ... operation of Lockton Companies, announced the addition of ... Foerster will join Lockton Dunning,s Pharmacy Consulting team, ... years of relevant industry experience to the position.  ... Managed Market Sales at Diplomat Specialty Pharmacy, where ...
Breaking Medicine Technology:Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2Kim Foerster Joins Lockton Companies 2
... Vermillion, Inc.,(OTC Bulletin Board: VRML) announced today that ... Strategic Alliance Agreement between the parties,through October, 2009. ... on the development and commercialization of two tests, ... to identify women with ovarian tumors that,are at ...
... bone mineral density at the,lumbar spine and total ... inhalation powder) and salmeterol, - Study provides ... patients,with COPD, PHILADELPHIA, Oct. 29 GlaxoSmithKline ... study of patients with,Chronic Obstructive Pulmonary Disease (COPD) ...
Cached Medicine Technology:Vermillion Renews Strategic Alliance Agreement With Quest Diagnostics, Inc. 2Vermillion Renews Strategic Alliance Agreement With Quest Diagnostics, Inc. 3Vermillion Renews Strategic Alliance Agreement With Quest Diagnostics, Inc. 4Study Found That Long Term Use of Advair Diskus(R) 250/50 Did Not Adversely Affect Bone Loss in Patients with COPD 2Study Found That Long Term Use of Advair Diskus(R) 250/50 Did Not Adversely Affect Bone Loss in Patients with COPD 3
(Date:12/26/2014)... 26, 2014 Parker & Sons, ... best in heating, cooling and plumbing contractor services ... emergency services in 2014 with regard to air-conditioning ... Arizona is known for its incredibly hot summers. ... the intricacies and details of a wide variety ...
(Date:12/25/2014)... Dallas, TX (PRWEB) December 26, 2014 ... and Market Analysis to 2023” focuses on the ... commercial opportunities in the colorectal cancer market. Stivarga ... treatment of colon or rectal cancer. Boehringer Ingelheim ... inhibitor, for the treatment of refractory CRC in ...
(Date:12/25/2014)... Recently, iFitDress.com, the popular online supplier of wedding dresses and ... of black one-shoulder cocktail dresses . In addition, all ... at discounted prices, up to 70% off. , ... weeks only. You know, we have thousands of frequent callers ... new items can visit our website for more details. The ...
(Date:12/25/2014)... 2014 BambooFlooringChina.com sells many bamboo products ... flooring. Today, the company announces big discounts on ... and colors. , BambooFlooringChina.com is the world’s leader in ... is valid until Jan. 20, 2015. , The bamboo ... with a natural thread. All the bamboo strips for ...
(Date:12/25/2014)... Dennis Thompson HealthDay Reporter ... with complex chronic illnesses can receive effective, less expensive care ... easy access to a team of dedicated health care professionals, ... become seriously ill and need either hospitalization or a trip ... enhanced medical home clinic at the University of Texas in ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 2Health News:Coordinated Care Through 'Medical Home' Best for Chronically Ill Kids: Study 3
... tamoxifen, switching to an aromatase inhibitor within three years ... The study reveals that the clear survival benefit was ... other causes – a significant risk associated with tamoxifen. ... significant impact on the survival rates of women with ...
... top Spanish fashion show, the Pasarela Cibeles, has rejected five models ... said. ,"Some of the girls were rejected due to ... of being 1.80 meters and weighing less than 50 kg," said ... other doctors. ,Although some models reach the body mass ...
... Socrates is smiling. His move to lift a ban on abortion ... in favor of the ban being lifted or, legalizing abortion. ... catholic nations that prohibit abortion or destruction of unborn children, due ... up to 3 years prison term and those who aid them ...
... to be monitored more carefully according to reports sounded ... are at a higher risk of giving birth to still-born ... Bahtiyar of Yale School of Medicine, who put forward results ... study. ,It was seen that the risk of ...
... increases a woman’s risk of becoming infected with HIV, ... edition of The Journal of Infectious Diseases (now online). ... sexually transmitted infections increase the risk of transmission and ... of Trichomonas vaginalis per year worldwide, there are few ...
... at least 90 per cent copper completely eliminate E. coli ... properties of the metal. ,The study gives machine ... of metals they use to coat the insides of their ... eliminating E coli contamination in their products. E. Coli O157:H7 ...
Cached Medicine News:Health News:Early Switch to an Aromatase Inhibitor Increases Survival 2Health News:Vaginalis Increases the Risk of Becoming Infected With HIV 2Health News:Vaginalis Increases the Risk of Becoming Infected With HIV 3Health News:Copper Alloys Surfaces Touted As Pathogen Killers 2
In microbiological laboratories and for in vitro fertilization, as well as in cancer research or tissue engineering, the Heraeus CO2 incubator BBD 6220 provides the best contamination protection and ...
... Steri-Cult has been the ... high volume cell culture for ... Its the name that brought ... infrared CO 2 sensors,microprocessor ...
IR Autoflow Dual Chamber Over-Under Water-Jacketed CO 2 Inc....
IR Autoflow Single Chamber Water-Jacketed CO2 Incubator...
Medicine Products: