Navigation Links
Data Presented at AACR Annual Meeting Show Anti-Tumor Activity of Peregrine's Fully Human Anti-PS Antibody in Prostate Cancer Model
Date:4/22/2009

-Preclinical Results Further Validate Significant Anti-Tumor Potential of Fully Human Anti-PS Antibodies and Expand the Company's PS-Targeting Platform-

-Treatment with Mouse Equivalent to the Human Antibody Inhibited Tumor Growth in a Prostate Cancer Model by More than 90%-

DENVER and TUSTIN, Calif., April 22 /PRNewswire-FirstCall/ -- Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM), a clinical stage biopharmaceutical company developing monoclonal antibodies for the treatment of cancer and serious virus infections, today announced that preclinical data presented during the AACR 100th Annual Meeting 2009 shows that one of its fully human phosphatidylserine (PS)-targeting antibodies demonstrated encouraging signs of efficacy in a preclinical model of prostate cancer. These positive new data validate the anti-tumor potential of this human anti-PS antibody, which is similar to Peregrine's lead clinical stage antibody bavituximab and extends Peregrine's anti-PS antibody pipeline. Bavituximab is in Phase II clinical trials for the treatment of advanced breast cancer and non-small cell lung cancer.

Peregrine's PS-targeting antibodies bind to the cellular membrane component PS that is usually located inside cells, but which becomes exposed on the external surface of the cells that line the blood vessels of tumors (the tumor vascular endothelium), creating a specific target for anti-cancer treatments. By binding to PS, the antibodies are believed to help mobilize the body's immune system to destroy the tumor and the tumor blood vessels.

In today's presentation, researchers from UT Southwestern Medical Center in Dallas and Affitech A/S reported that similar to bavituximab, the human antibody PGN635 targets and binds specifically to the tumor vascular endothelium(1). Treatment with androgen deprivation therapy or docetaxel substantially increased the percentage
'/>"/>

SOURCE Peregrine Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
2. Pre-clinical Data on Recent Advances with HIV VLP Vaccine Presented at AIDS Vaccine 07 Conference
3. New Study Presented at WorldSleep 2007 Demonstrates Ramelteon Has Sustained Efficacy Over Six Months in Adults With Chronic Insomnia
4. Genasense(R) Data in Melanoma to be Presented in Opening Session at First Worldwide Melanoma Center Meeting of the European Association of Dermato-Oncology
5. Ozarelix Phase 2 Data Presented at 29th Congress of the Societe Internationale dUrologie
6. GeoVax Successful HIV/AIDS Vaccine Trial Data Presented at AIDS Vaccine 2007 Conference
7. Study Results for Aclidinium Bromide, a Novel Anticholinergic, Presented at European Respiratory Society Annual Congress
8. Promising Data from Paratek Pharmaceuticals MAR Inhibitor Program Presented in Late Breaker Session at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
9. New Phase III Data Presented for Once Monthly Dosing Regimen of Risedronate to Treat Postmenopausal Osteoporosis
10. Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
11. Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/3/2015)... Research and Markets ( http://www.researchandmarkets.com/research/sd9xxh/radiology ) has announced the ... Type, Deployment Mode, End User and by Component - ... their offering. The global radiology information ... is projected to reach $722.7 Million by 2019, at ... The global radiology information system market has ...
(Date:9/3/2015)... NEW YORK , Sept. 3, 2015  The ... News are raising disturbing questions about the company,s handling ... Liebhard LLP reports.  On September 2 nd , ... than 300 adverse events, including at least 27 fatalities, ... also disclosed a confidential study commissioned by C.R. Bard ...
(Date:9/3/2015)... Research and Markets ( http://www.researchandmarkets.com/research/84p6xc/investigation ) ... on China,s Bromhexine Market, 2010-2019" report to their ... of respiratory disease keeps growing and so does the ... of vasicine, is a mucolytic agent used in the ... or excessive mucus. It can make the phlegm thinner ...
Breaking Medicine Technology:Radiology Information Systems Market Report 2015 - Global Trends & Forecast to 2019 for the $700+ Million Industry 2Radiology Information Systems Market Report 2015 - Global Trends & Forecast to 2019 for the $700+ Million Industry 3IVC Filter Lawsuit News: NBC News Investigation into C.R. Bard Recovery Filters Raises Disturbing Questions, Bernstein Liebhard LLP Reports 2IVC Filter Lawsuit News: NBC News Investigation into C.R. Bard Recovery Filters Raises Disturbing Questions, Bernstein Liebhard LLP Reports 3China Bromhexine Market Report 2015-2019 2
(Date:9/3/2015)... , ... September 03, 2015 , ... ... Florida Companies to Watch for 2015 by economic development group GrowFL and ... 50 companies in the state selected for this prestigious award, which recognizes growing ...
(Date:9/3/2015)... (PRWEB) , ... September 03, 2015 , ... The first ... covering the allegations made by IVC filter lawsuits filed against Bard.** These ... harmed when a Bard IVC filter broke or failed, have recently been consolidated for ...
(Date:9/3/2015)... ... September 03, 2015 , ... ... providers, has been retained to lead a national chief executive officer ... search firms in the healthcare industry, B. E. Smith has recently placed more ...
(Date:9/3/2015)... ... September 03, 2015 , ... ... its upcoming virtual conference, “Proven Pharmacy Benefit Strategies for a Rapidly Changing Marketplace.” ... Health, Express Scripts and Milliman, will discuss how plan sponsors are adopting bold, ...
(Date:9/3/2015)... ... September 03, 2015 , ... ... simplifying responsibilities which can impact the delicate life balance between work and leisure ... be.” - Jeffrey R. Leaptrott, CEO , A LifeMinder Plus® Emergency Care Document ...
Breaking Medicine News(10 mins):Health News:IQ Formulations Hailed Among Florida Companies to Watch for 2015 2Health News:IQ Formulations Hailed Among Florida Companies to Watch for 2015 3Health News:Bard IVC Lawsuit Allegations Reach National Prime Time News 2Health News:Bard IVC Lawsuit Allegations Reach National Prime Time News 3Health News:Melissa Memorial Hospital Retains B. E. Smith to Recruit New CEO 2Health News:Melissa Memorial Hospital Retains B. E. Smith to Recruit New CEO 3Health News:Speakers for Upcoming AIS Virtual Conference on Pharmacy Benefit Strategies Include Executives from CVS Health, Express Scripts 2Health News:LifeMinder Plus® Announces Emergency Care Document Set Giveaway for America 2Health News:LifeMinder Plus® Announces Emergency Care Document Set Giveaway for America 3
... Bashas, Food City & AJ,s grocery stores sell limited-edition, ... 8 Dodge the age-old question of "paper or ... Arizona and support Phoenix Children,s Hospital. Bashas, Food City ... Eggs, Holsum Bakery and Shamrock Farms on a charitable ...
... April 8 The following is a statement by ... http://www.newscom.com/cgi-bin/prnh/20080918/CFTFKLOGO )Rhode Island,s leaders have taken decisive action to ... toll of tobacco use by increasing the state cigarette ... the highest state cigarette tax in the nation. ...
... April 8 James Trantham, DMD, is ... new dental practice, DellagioDentist.com, a new, full-service, ... dental practice, located at 7940 Via Dellagio ... http://www.newscom.com/cgi-bin/prnh/20090408/CG96485 )Dr. Trantham and his dental team ...
... A new study conducted at Mayo Clinic reports that ... drugs for Parkinson,s disease develops new-onset, potentially destructive behaviors, ... audio and video resources including excerpts from an interview ... available on the Mayo Clinic News Blog. , ...
... Much They Will Pay for Treatment and How ... ARBOR, Mich., April 8 As people take ... employers and health insurers need better ways to ... about their health and use of healthcare services.To ...
... $12.9 Billion in Lost Productivity and $3.3 Billion in ... Reform Needed to Address Health Costs and Economic Loss ... -Health experts and statewide leaders representing over 50 ... together in Hartford at the State Capitol at noon ...
Cached Medicine News:Health News:Hometown Grocer, Local Food Companies Team up to Support Pediatric Patients, Encourage 'Green' Lifestyle 2Health News:Hometown Grocer, Local Food Companies Team up to Support Pediatric Patients, Encourage 'Green' Lifestyle 3Health News:Hometown Grocer, Local Food Companies Team up to Support Pediatric Patients, Encourage 'Green' Lifestyle 4Health News:Rhode Island Cigarette Tax Increase Delivers Victory for Kids and Taxpayers; $1 Increase Gives State Highest Cigarette Tax in the Nation 2Health News:New Family Dental Practice Opens in Orlando 2Health News:Parkinson's disease medication triggers destructive behaviors 2Health News:HealthEquity, a Leading Healthcare Account Administrator, Licenses Thomson Reuters Information Solutions to Help People Make Better Healthcare Decisions 2Health News:HealthEquity, a Leading Healthcare Account Administrator, Licenses Thomson Reuters Information Solutions to Help People Make Better Healthcare Decisions 3Health News:Bipartisan Coalition Forms to Call for Chronic Disease to be Key Focus of Health Reform in Connecticut and Nationally 2Health News:Bipartisan Coalition Forms to Call for Chronic Disease to be Key Focus of Health Reform in Connecticut and Nationally 3
Straight shafts with 2.0 mm, 1 x 2 Elschnig style teeth. Serrated handle with polished finish. Handle: Wide....
Straight shafts with 45 degrees, 0.12 mm, 2 x 3 teeth and tying platform. Serrated handle with polished finish....
Straight shafts with 0.1 mm Pierse tips. Flat smooth handle with dull finish....
Straight shafts with micro Pierse type tips. Flat open serrated handle, dull finish....
Medicine Products: