Navigation Links
Data From Landmark Clinical Trial of Abbott's MitraClip® System Demonstrate Durable Clinical Benefits for Patients With Mitral Regurgitation Two Years After Treatment
Date:4/4/2011

NEW ORLEANS, April 4, 2011 /PRNewswire/ -- Abbott (NYSE: ABT) today announced data from its EVEREST II (Endovascular Valve Edge-to-Edge REpair STudy) study showing that patients with significant mitral regurgitation (MR) treated with the company's investigational percutaneous catheter-based MitraClip® system continue to demonstrate the clinical benefits of initial treatment shown at one year out to two years, including improvements in heart function and reductions in symptoms. EVEREST II is the first randomized clinical trial to compare a catheter-based mitral valve device to mitral valve surgery. Data from the study were published in The New England Journal of Medicine and presented in a late-breaking clinical trial session at the American College of Cardiology's (ACC) 60th Annual Scientific Session and i2 Summit 2011 in New Orleans.

At two years after treatment, data from 279 patients from the EVEREST II trial demonstrated a clinical success rate of 51.7 percent for patients treated with the MitraClip device compared to a clinical success rate of 66.3 percent for surgery patients (p=0.04) on an Intention-to-Treat (ITT) basis. These results compare with the one-year data, which demonstrated a clinical success rate of 55.2 percent for patients who received the MitraClip device, compared to a clinical success rate of 73.0 percent for surgery patients (p=0.0007). The clinical success rate is defined as freedom from death, from surgery for valve dysfunction, and from moderate to severe MR (3+ or 4+).

In The New England Journal of Medicine, the study authors, who represent a variety of specialties including cardiac surgery and interventional cardiology, state that "although percutaneous repair was less effective at reducing mitral regurgitation than surgery before hospital discharge, at 12 and 24 months the rates of reduction in mitral regurgitation were
'/>"/>

SOURCE Abbott
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Data From Landmark Study Evaluating Gender Differences in Response to an HIV Therapy Published in Annals of Internal Medicine
2. Landmark National Survey Conducted by Harris Interactive® Sheds Light on Hidden Problem of Heavy Monthly Periods
3. The New England Journal of Medicine Publishes Results of Landmark CREST Study, Showing Similar Positive Outcomes for Abbotts Carotid Stent System and Surgery
4. US HIFU to Fund Landmark Investigation of Focal Therapy for Prostate Cancer
5. BioMed Realty Trust Signs New Lease With Regeneron Pharmaceuticals for 131,000 Square Feet at Landmark
6. Landmark Study in The Lancet Oncology Shows Capecitabine (Xeloda(R)) Combination Therapy Reduces Early Breast Cancer Recurrence
7. ATS Medical Announces FDA Approval for a Landmark Clinical Investigation of the ATS 3f Aortic Bioprosthesis
8. Landmark Study for GSKs Cervical Cancer Vaccine Published in The Lancet
9. Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results
10. Landmark Study in The New England Journal of Medicine Shows HPV Testing Significantly Reduces Deaths from Cervical Cancer, Compared to other Methods Including Pap
11. New England Journal of Medicine Publishes Results from Boston Scientifics Landmark SYNTAX(TM) Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... Pa. , July 10, 2014 ... Moberg Research,s (Moberg) medical device manufacturing facility. Rep. ... Moberg,s advanced neurological monitors facilitate cutting-edge research in ... Rep. Kennedy and mental health advocate, Garen ... organization dedicated to fostering fundamental changes that will ...
(Date:7/10/2014)... LAVAL, Quebec , July 10, 2014  Valeant ... TSX: VRX) today announced it has completed the sale ... Sculptra, and Dysport owned or held by Valeant for ... agreement with Nestle S.A, which recently completed its acquisition ... complete the divestiture of our products to a company ...
(Date:7/10/2014)... July 10, 2014  Decision Resources Group finds ... disease (ID) specialists are willing to prescribe Durata,s ... for use as OPAT, approximately two-thirds of the ... to their hospital inpatients. However, our findings indicate ... are initiated on OPAT following hospital discharge, and ...
Breaking Medicine Technology:Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 3
... 2011 An Illinois high school hockey coach is ... Tim Johannes, who coaches at Stevenson High ... anyone wearing helmets with the risk of sustaining a ... The Shockwave System is a three-step system, ...
... Pharmaceutical, Inc., a leading national wholesale distributor of pharmaceutical ... A. Corona to president and COO. Corona, ... Masters in 2002 and under his tenure has helped ... "Wayne has contributed greatly to our growth, ...
Cached Medicine Technology:Shockwave System Developed to Aid Concussion Detection 2
(Date:7/13/2014)... Wright & Schulte LLC has learned that the ... of 2015, in U.S. District Court, District of South ... process in the South Carolina federal court where ... multidistrict litigation (MDL). The complaints pending in the Louisiana ... that they took the statin medication to lower their ...
(Date:7/13/2014)... July 13, 2014 Celebrity fitness trainer ... formed a promotional partnership with Aqua Health Labs for ... Omega-3 EPA supplement . The collaboration was recently announced ... fitness trainer , actor, model, and a two ... for A-List celebrities, he has prepared stars including Demi ...
(Date:7/13/2014)... 2014 Hope Palliative & Hospice Care announced ... group at the Tamarack Senior Living Community in Palatine, IL. ... A.M. on the 3rd Wednesdays of every month. This ... Tamarack Community located at 55 S. Greeley St. Palatine, IL ... there is no cost for the group. , “A ...
(Date:7/13/2014)... 2014 According to The Peripheral Neuropathy ... comprehensive program that teaches people how to deal with ... without medications. This program also provides people with safe ... neuropathy , including numbness, prickling, burning, and intense stabbing ... this home treatment program can help people eliminate some ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Recently, iFitDress.com, ... and women’s special occasion outfits, has added a new ... website. Furthermore, the company has launched a promotion for ... discount. , iFitDress.com is now providing thousands of ... products sell well in Britain, America, France, Italy and ...
Breaking Medicine News(10 mins):Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 2Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 3Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 4Health News:Celebrity Fitness Expert Supports Revolutionary New Health Supplement 2Health News:Hope Hospice Announces Grief Support Group at the Tamarack Senior Living Community 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 3Health News:New and Beautiful Evening Dresses Unveiled by iFitDress.com 2
... Court on Monday upheld a ban on a teenager from wearing ... sex before marriage. ,Lydia Playfoot, 16, said she ... school, the Millais School in Horsham, West Sussex, denies infringing her ... of the Christian faith and violates its uniform policy. ...
... Illinois at Chicago have created a theoretical blueprint for ... , ,Scientists say the propeller opens the possibility ... out of cells. ,, ,Petr Krl, Assistant ... used classical molecular dynamics simulations to learn how tiny ...
... webcams and other new technological innovations have transformed the ... an international congress of the deaf said Tuesday. ... the internet, internet, webcams, email, SMS and chat ... institute for the deaf in the eastern city of ...
... the world. Perhaps one way out could be treating everyone ... , Sir Liam Donaldson, Englands Chief Medical Officer has suggested. ... leads to the deaths of hundreds of patients on waiting ... cent of people want to donate their organs after death, ...
... to a study published Neurology, the medical journal of the ... perform worse in school than healthy kids , grades in ... harder time than boys in getting good grades. ... grades and subjects of brain tumor survivors have been reported. ...
... A few months back, the Food and Drug Administration approved ... effective at preventing pregnancy as the other pills already in ... who take it will never get their periods. ... may never be the same- it may disappear altogether. ...
Cached Medicine News:Health News:New Technology Transforming Life for the Deaf 2Health News:Treat Every Patient as a Potential Organ Donor, British Health Official Says 2Health News:Brain Tumor Children Poor Performance in Schools 2Health News:The Queen Of All Contraceptives Released 2
Triad Plus PVP-I Scrub Solution has broad-spectrum germicidal action.This special formula is designed to help break down body oils and yet limit the bubbles the surfactants allowing easy removal and ...
... Solution is the ... povidone-iodine. It is a ... kills gram-positive and gram-negative ... organisms), as well as ...
... allows the user to prep one uniform, ... less than 2-minutes. It also utilizes the ... scrubbing and healthcare personnel handwashing. ACTIPREP also ... a tacky surface for drapes to adhere ...
... Aplicare's disposable 1-ounce pouches are designed ... reducing waste. They are used in nursing ... emergency rooms and many other hospital departments. ... which is a mild antiseptic, germicidal and ...
Medicine Products: