Navigation Links
Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting
Date:11/7/2008

PHILADELPHIA, Nov. 7 /PRNewswire/ -- Data from an investigational, open-label, randomized study assessing extended dosing regimens of PROCRIT(R) (Epoetin alfa) in treating anemia in subjects with Stages 3 - 4 chronic kidney disease (CKD) were presented today at the American Society of Nephrology 41st Annual Meeting.

All three dosing groups, including the FDA-approved three-times-per-week (TIW) regimen, plus once-a-week (QW) and once-every-two-weeks (Q2W) investigational regimens, achieved a mean final hemoglobin (Hb) within the range of 11.0 - 11.9 g/dL. Based on the increases in Hb, the QW and Q2W investigational regimens were statistically non-inferior to the TIW regimen (lower limits of 95 percent confidence intervals [CIs] within the non-inferiority margin of -1 g/dL).

The percent of subjects with Hb exceeding 11.9 g/dL during the first 22 weeks of treatment was higher in the TIW group (86.2 percent) than in the QW (78.4 percent) and Q2W (71.2 percent) groups; the median per-subject frequency of Hb exceeding 11.9 g/dL was 6, 4 and 3 times for the TIW, QW and Q2W groups, respectively.

In the first 22 weeks of treatment, the proportion of subjects experiencing serious adverse events (SAEs) was 15 percent in the TIW group, compared with 22 percent in both the QW and Q2W groups. During the entire 44 weeks of treatment, the proportion of subjects experiencing SAEs was 29, 33 and 33 percent in the TIW, QW and Q2W groups, respectively. The number of subjects with investigator-confirmed thromboembolic vascular events (TVEs) over the first 22 weeks was 2 in the TIW, 2 in the QW and 3 in the Q2W groups; over 44 weeks, these numbers were 2, 5 and 8 in the TIW, QW and Q2W groups, respectively. The number of subjects who died during the first 22 weeks was 0 in the TIW, 6 in the QW and 3 in the Q2W groups. Over 44 weeks, 4, 6 and 4 subjects died, respectively. None of the deaths were considered related to the study drug.

"These data provide
'/>"/>

SOURCE Ortho Biotech Products, L.P.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
2. A Worldwide Phase III Clinical Trial Seeks U.S. Patients to Explore Investigational Drug Phenoxodiol
3. Ardea Biosciences, Inc. Announces Completion of Phase 1 Clinical Trials of Novel Investigational HIV Drug RDEA806
4. ECLIPSE Data on Effects of Otsukas Investigational Novel Treatment, Tolvaptan, on Advanced Heart Failure Patients Hemodynamics and Urine Output Featured in Heart Failure Society of Americas Late Breaking Trials
5. Replidynes Investigational Antibacterial Agent REP3123 Prevents Sporulation in Clostridium difficile
6. Replidynes Investigational Antibacterial Agent REP3123 Prevents Toxin Production in Clostridium difficile
7. Wyeth Presents Phase 3 Fracture Data for Bazedoxifene, an Investigational Therapy for Osteoporosis
8. Newly Published Phase II Study Shows the Investigational Drug Vandetanib Prolongs Progression-Free Survival in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)
9. KineMed Presents Preclinical Data for Investigational Agent Demonstrating Neurogenesis and Confirming Improvements in Behavioral Model
10. Lexicon Reports Initial Clinical Trial Results for LX1031, an Investigational New Drug for Irritable Bowel Syndrome
11. Roches Investigational Polymerase Inhibitor, Combined with PEGASYS(R) and COPEGUS(TM), Shows Potent Antiviral Activity in Treatment of Chronic Hepatitis C at Four Weeks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... , Oct. 20, 2014  Indianapolis interventional ... Toronto -based 3D visualization leader ... Congress of Neurological Surgeons Annual Meeting that they ... for brain surgery. The collaboration is the first ... combination to improve patient outcomes. NICO,s BrainPath® interventional ...
(Date:10/20/2014)...  ResMed (NYSE: RMD ) today ... program, a comprehensive suite of software and service ... health care providers. ResMed Data ... information. It integrates valuable sleep and respiratory treatment ... platforms with customers, in-house or third-party electronic health ...
(Date:10/20/2014)... , Oct. 20, 2014   BioNano Genomics announced ... the ability to collect human data at 30X depth, sufficient ... chip.  This new capability was established and demonstrated for the ... Irys TM System and will be rolled out ... BioNano will be showcasing this advancement at the American ...
Breaking Medicine Technology:Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 4Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 5ResMed Launches ResMed Data Exchange 2BioNano Genomics Announces One Human : One Chip : One Day 2BioNano Genomics Announces One Human : One Chip : One Day 3
... Pharmaceutical Institute, the leading provider of specialized ... and a subsidiary of Campbell Alliance, announced today ... Therapeutic Area Essentials™ e-course series. ... pharmaceutical and biotech R&D and commercial professionals.  It ...
... (SMEV.PK), the manufacturer and developer of medical, aesthetic, weight ... has been invited to present at the National Eagles ... tomorrow, Tuesday, June 21, 2011, at the prestigiously renowned ... NEAA is a national alliance of institutional and individual high ...
Cached Medicine Technology:Therapeutic Area Essentials "Class of 2011" Brings Current Disease State Training to Pharma 2Simulated Environment Concepts to Present at National Eagles and Angels Association New York Meeting 2
(Date:10/20/2014)... Do you ever feel difficulty in ... wonderful app Metassessor for teachers, specialists and parents. SIMpalm, ... its client “Intervention Development LLC” to launch Metassessor App ... for iOS 4.3 or later and is Compatible with ... for iPhone 5. It is now available on Apple ...
(Date:10/19/2014)... BambooIndustry.com, one of the most popular suppliers of bamboo ... deckings . Moreover, the company has launched a special ... at deeply discounted rates. , As is known ... significance of online business nowadays. Thus, BambooIndustry.com pays a ... are striving to deliver both value and efficiency for ...
(Date:10/19/2014)... Having been working in the garment industry for ... needs. According to James, one of the company’s top designers, ... with high-low skirts that add beauty to them. Chiffon floor ... has unveiled its new selection of 2014 long prom dresses. ... new items are available in over 20 popular designs. The ...
(Date:10/19/2014)... SweetDressy.com, a professional company of women’s dresses and ... evening dresses . All the company’s old and ... discount is up to 66 percent off. , ... fashion field. Its dress specialists are striving to make ... of the world. All the company’s items are unique, ...
(Date:10/19/2014)... stem cell-based research could improve understanding of intestinal diseases ... suggests. Scientists used stem cells to grow "organoids" ... They then transplanted the organoids into mice, creating a ... researchers. "This provides a new way to study ... failure, from genetic disorders appearing at birth to conditions ...
Breaking Medicine News(10 mins):Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 2Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 3Health News:High Quality Bamboo Deckings, New Items Unveiled By BambooIndustry.com 2Health News:2014 Long Prom Dresses From LunaDress Now Available In Over 20 Popular Designs 2Health News:Promotion For Beautiful Long Evening Dresses Launched By SweetDressy.com 2Health News:Scientists Grow, Implant Human Intestinal Tissue in Mice 2
... Tuesday, November 13, 8:00 EST -, SOUTH ... Sheets: VXGN), a biopharmaceutical company, and Raven,biotechnologies, inc., ... monoclonal antibody therapeutics (MAbs) for treating cancer, announced,today ... approved a,definitive merger agreement. The merger is expected ...
... WARSAW, Ind., Nov. 12 Symmetry Medical Inc.,(NYSE: ... to the global orthopedic,device industry and other medical ... review of accounting irregularities at its Sheffield,UK operating ... estimate that the,overstatement of revenue and income before ...
... time, researchers add , MONDAY, Nov. 12 (HealthDay News) -- ... late in youngsters with attention deficit hyperactivity disorder (ADHD), their ... by researchers at the U.S. National Institute of Mental Health ... in children with ADHD was most prominent in regions at ...
... 2007) The Foundation for the Scientific Study of Sexuality ... Award to Rutgers College of Nursing emerita faculty member Beverly ... its 50th anniversary meeting of the Society for the Scientific ... Bonnie and Vern L. Bullough Award is given by FSSS ...
... U.N. Environmental Initiative to Pittsburgh, PITTSBURGH, ... and social responsibility, today Bayer,employee-volunteers and Chartiers ... grabbed their spades and planted trees on ... it has joined the United,Nations Environment Programme,s ...
... Nov. 12 ULURU Inc. (Amex:,ULU) today announced that ... quarter 2007 financial results and provide a general business ... Time with Kerry P.,Gray, President and CEO. To ... for,international callers dial (850) 429-1388 (access code 9283#) five ...
Cached Medicine News:Health News:VaxGen and Raven biotechnologies Announce Signing of Definitive Merger Agreement 2Health News:VaxGen and Raven biotechnologies Announce Signing of Definitive Merger Agreement 3Health News:VaxGen and Raven biotechnologies Announce Signing of Definitive Merger Agreement 4Health News:VaxGen and Raven biotechnologies Announce Signing of Definitive Merger Agreement 5Health News:VaxGen and Raven biotechnologies Announce Signing of Definitive Merger Agreement 6Health News:Symmetry Medical Provides Update of Previously Disclosed Accounting Review at Sheffield, UK Operating Unit 2Health News:Symmetry Medical Provides Update of Previously Disclosed Accounting Review at Sheffield, UK Operating Unit 3Health News:Symmetry Medical Provides Update of Previously Disclosed Accounting Review at Sheffield, UK Operating Unit 4Health News:ADHD Delays Growth of Certain Brain Areas 2Health News:Rutgers College of Nursing emerita professor Beverly Whipple receives FSSS book award 2Health News:Bayer Plants Trees With Chartiers Valley Intermediate School Students, Provides Free Environmental Education Materials 2Health News:Bayer Plants Trees With Chartiers Valley Intermediate School Students, Provides Free Environmental Education Materials 3Health News:Bayer Plants Trees With Chartiers Valley Intermediate School Students, Provides Free Environmental Education Materials 4Health News:ULURU Inc. Announces Conference Call to Discuss Financial Results for the Third Quarter Ended September 30, 2007 and Provide a Business Update 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: