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Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke
Date:9/2/2014

BARCELONA, Spain, September 2, 2014 /PRNewswire/ --


-- GARFIELD-AF Registry presentations at ESC CONGRESS 2014 provide insight into treatment and outcomes of patients at risk of stroke in everyday clinical practice -- 

Data from nearly 12,500 patients enrolled in the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF), an innovative, independent academic research initiative, have illustrated that stroke prevention strategies for atrial fibrillation (AF) patients remain sub-optimal despite the transition to a new era of anticoagulation featuring non-vitamin K antagonist oral anticoagulant (NOAC) therapies. The findings, presented this week at ESC Congress 2014, show that treatment patterns in everyday clinical practice are not consistent with evidence-based guidelines, and that inappropriate use and under-use of anticoagulant therapy is associated with worse outcomes for patients.

GARFIELD-AF is led by an international steering committee under the auspices of the Thrombosis Research Institute (TRI), London, UK. It is an observational study designed to clarify evolving AF treatments and outcomes for patients, clinicians and healthcare providers. Most existing data about AF have come from controlled clinical trials, whilst the burden on patients and populations in everyday clinical practice is less well understood. Up to 2% of the population has AF,[1] a common heart rhythm disorder that can lead to life-threatening complications, including stroke. Despite the availability of highly effective preventive treatments, AF-related stroke remains a major and increasing clinical and societal burden.

"The latest data from GARFIELD-AF illustrate that the introduction of innovative therapies has begun to alter the way AF patients are treated to prevent stroke," said Professor Lord Ajay Kakkar, Professor of Surgery a
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