Navigation Links
Data Confirm Synvista Therapeutics Haptoglobin Diagnostic Test Kit Success in Rapidly Determining Cardiovascular Risk in Patients with Diabetes
Date:9/11/2008

d paper was presented at the Symposium highlighting the use of Synvista's proprietary diagnostic kit for quantifying carboxymethyl-lysine (CML), a dominant advanced glycation end product (A.G.E.). The study demonstrated that CML is a biomarker of mortality in the elderly.

About Haptoglobin

The best understood function of haptoglobin (Hp), a common serum protein, is to bind free hemoglobin released from red blood cells. Extracellular hemoglobin (hemoglobin not found in red blood cells) is a potent oxidizing agent capable of inflicting oxidative tissue damage. Haptoglobin binds to this extracellular hemoglobin and inhibits hemoglobin induced oxidation. Once hemoglobin is bound to haptoglobin, it is rapidly cleared from the bloodstream by the liver or specialized white blood cells.

Haptoglobin in humans exists as three different proteins that arise from one of three haptoglobin gene combinations in the population, Hp 1-1 (16%), Hp2-2 (36%) and Hp1-2 (48%) For a variety of reasons, well described in the literature, Hp2-2 is more effective than Hp1-1 at preventing hemoglobin-induced oxidation in the bloodstream and blood vessel wall.

As a result, scientists have determined that the rate of heart disease is five times higher in Hp2-2 Diabetes than in Hp1-1 Diabetes. Hp2-2 Diabetes also has higher rates of myocardial infarction and re-vascularization within one year of angioplasty, and of heart failure and death following a heart attack. Prospective clinical trials have demonstrated that the rate of heart attack in Hp2-2 Diabetes can be decreased by the administration of natural Vitamin E (400IU). This combination of testing and treatment exemplifies pharmacogenomics, the targeting of a particular drug on the basis of genetic testing.

About Synvista Therapeutics

Synvista Therapeutics is a biopharmaceutical company developing diagnostics and drugs to diagnose, treat and prevent cardiovascular disease in people with diabetes. The Com
'/>"/>

SOURCE Synvista Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Novo Nordisk New Data From a Phase 3 Study Confirms Clinical Benefits of Once-Daily Liraglutide in the Management of Type 2 Diabetes
2. Progen Terminates PATHWAY Trial & Confirms Focus on Potential High Value Molecules and M&A
3. Positive Phase I/II Data of IDX899 Confirm Potent Antiviral Activity and Favorable Safety Profile in Treatment-Naive HIV-Infected Patients
4. PTC Therapeutics Announces Data from Additional Clinical Studies of PTC124 in Cystic Fibrosis Confirming Activity
5. New Meta-Analysis Confirms Safety Profile for NeoRecormon in Treating Anaemia in Cancer Patients
6. New Data From Head-to-Head Study Confirms Once-Daily Levemir(R) is as Effective as Glargine over a 24-Hour Period in Subjects with Type 2 Diabetes
7. University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients
8. Study Confirms That Avastin Significantly Increases Chance of Living Without Disease Progression in Metastatic Breast Cancer
9. Data Confirm Avastin(R) Helps Patients With Metastatic Colorectal Cancer Live Even Longer
10. AviaraDx Confirms That Combination of Two Molecular Biomarkers Improves Prediction of Disease Recurrence in Early Stage Breast Cancer Patients
11. New Study Confirms Dose-Accuracy of SoloSTAR(R) Prefilled Insulin Pen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... 2014  El Camino Hospital, a leader in the ... the Leaf Patient Monitoring system to help prevent hospital-acquired ... patients susceptible to bed sores. The decision ... of the system, which showed dramatic improvement in compliance ... is the one of the most effect ways to ...
(Date:7/30/2014)... 2014  Decision Resources Group finds that ... research imaging system market will be significantly driven ... combining computed tomography and magnetic resonance imaging with ... from the need for higher-quality imaging to satisfy ... will spur preclinical imaging system sales. ...
(Date:7/30/2014)... July 30, 2014 Stryker brand ambassadors Fred Funk ... the 3M Championship Champions Tour event near Minneapolis, MN ... Blaine . Stryker is the official joint replacement products ... Starting Friday, August 1 st through Sunday, August 3 rd ... an on-site joint health destination located in the Pioneer Press Expo ...
Breaking Medicine Technology:El Camino Hospital Utilizes Cutting-Edge Leaf Patient Monitor System to Help Reduce Risk of Pressure Ulcers 2El Camino Hospital Utilizes Cutting-Edge Leaf Patient Monitor System to Help Reduce Risk of Pressure Ulcers 3Growing Popularity of Multimodality Imaging Will Drive the Preclinical Animal Research Imaging System Market 2Stryker Brand Ambassadors Fred Funk And Hal Sutton Set To Play At 3M Championship 2Stryker Brand Ambassadors Fred Funk And Hal Sutton Set To Play At 3M Championship 3Stryker Brand Ambassadors Fred Funk And Hal Sutton Set To Play At 3M Championship 4Stryker Brand Ambassadors Fred Funk And Hal Sutton Set To Play At 3M Championship 5
... ESRX ), one of the largest pharmacy benefit ... release its third quarter earnings on Tuesday, October 25, 2011 ... call to discuss third quarter results on Wednesday, October 26, ... This call is being webcast and can be ...
... YORK, Oct. 17, 2011 Levi & Korsinsky is investigating ... the "Company") (NASDAQ: ANDS ) for possible breaches ... connection with the sale of the Company to Roche Holding ... receive $3.70 in cash per share of Anadys stock they ...
Cached Medicine Technology:The Law Firm of Levi & Korsinsky, LLP Announces Investigation into Possible Breaches of Fiduciary Duty by the Board of Anadys Pharmaceuticals Inc. in Connection with the Sale of the Company to Roche Holding AG 2
(Date:7/30/2014)... Of the many sub-groups of cells jockeying for ... not be those that can proliferate the fastest, researchers ... in an advance online publication of the journal ... the treatment of cancer with precision medicines, the study ... are truly driving the tumor,s growth and metastasis and ...
(Date:7/30/2014)... According to the market research ... by Technology (ICS, MES, ERP, ITS), Field Devices, ... Application (Process, Discrete) - Global Forecast & Analysis ... Mexican market is expected to reach $6.99 Billion ... Browse 70 market data Tables and 96 Figures ...
(Date:7/30/2014)... Everyone knows that the internet is the absolute center of ... for something to buy, trying to reconnect with friends, or ... much always going to be the go to resource. That ... happy to announce the launch of their brand new website ... Whether a person wants to know what the Sierra Dental ...
(Date:7/30/2014)... July 30, 2014 Shabaikai is an ... forests of the Pomo Indians located on the shores ... the river Shabaikai, meaning ‘crooked snake’. Clarkson takes the ... and the violence of prohibition and organized crime, providing ... River. Here, the most powerful men in the world ...
(Date:7/30/2014)... Texas (PRWEB) July 30, 2014 “North ... key market data on the North America Contrast Media ... US dollars, and volume (in units) and average price ...     CT Injectors ,     Interventional Cardiology/Angio Injectors and ... (or contrast agent) is a substance used to enhance ...
Breaking Medicine News(10 mins):Health News:Target growth-driving cells within tumors, not fastest-proliferating cells 2Health News:Target growth-driving cells within tumors, not fastest-proliferating cells 3Health News:Mexico Factory Automation and Machine Vision Market Worth $6.99 Billion by 2020 - New Report by MarketsandMarkets 2Health News:Mexico Factory Automation and Machine Vision Market Worth $6.99 Billion by 2020 - New Report by MarketsandMarkets 3Health News:Mexico Factory Automation and Machine Vision Market Worth $6.99 Billion by 2020 - New Report by MarketsandMarkets 4Health News:Sierra Dental Releases New Website For Fort Lauderdale Residents 2Health News:Bill E. Clarkson Releases Debut Fact-Based Novel, Shabaikai 2Health News:Contrast Media Injectors Market in North America (US, Canada, Mexico) to 2020 Report Available at MarketOptimizer.org 2Health News:Contrast Media Injectors Market in North America (US, Canada, Mexico) to 2020 Report Available at MarketOptimizer.org 3Health News:Contrast Media Injectors Market in North America (US, Canada, Mexico) to 2020 Report Available at MarketOptimizer.org 4
... academics have been awarded funds from a huge European ... of individual people which could lead to everyone ... genetic and physiological make-up. Under the system, doctors ... of an individual patient,s health needs and medical history ...
... Steven Reinberg HealthDay Reporter , SUNDAY, July 24 ... new anti-clotting drug, Eliquis, to dual antiplatelet therapy may result ... and stroke, a new study finds. A trial evaluating ... severe bleeding among those taking Eliquis (apixaban) became apparent. ...
... July 23 (HealthDay News) -- Swimming may be easy on ... The most common injury among those who practice the ... percent of competitive swimmers, said Dr. Scott A. Rodeo, co-chief ... Special Surgery in New York City, who recently spoke at ...
... News) -- The ability of dolphins to resist infection and ... the treatment of human wounds, a researcher suggests. , ... documented," Dr. Michael Zasloff, adjunct professor at Georgetown University Medical ... news release. "How does the dolphin not bleed ...
... study by researchers at Drexel University,s School of Public Health ... gateway to the use of injected drugs such as heroin, ... drugs. The study, published in the International Journal of ... initiation into the misuse of opioid drugs. Common factors identified ...
... Amanda Gardner HealthDay Reporter , THURSDAY, July 21 ... Internet on their smartphones tend to hold the devices closer ... to work harder than usual, new research shows. This ... smartphones -- could put added strain on people who already ...
Cached Medicine News:Health News:Computer program could 'revolutionize the world's health care' 2Health News:Computer program could 'revolutionize the world's health care' 3Health News:Anti-Clotting Drug May Cause Severe Bleeding With No Benefit 2Health News:Anti-Clotting Drug May Cause Severe Bleeding With No Benefit 3Health News:Common Swimming Injuries Often Avoidable 2Health News:Dolphins' Superior Ability to Heal May Help Humans 2Health News:Drexel study: Misuse of pain medication is pathway to high-risk behaviors 2Health News:Drexel study: Misuse of pain medication is pathway to high-risk behaviors 3Health News:Smartphones May Be Taxing Your Eyes 2Health News:Smartphones May Be Taxing Your Eyes 3
... Medication Delivery., ,Designed for adolescent ... incorporates an additional lumen and injection ... the cuff., ,SHERIDAN offers three ... CO2 monitoring, pressure monitoring or medication ...
... For Laryngotracheal Instillation of Topical Anesthetic, ... populations, this cuffed tube incorporates an ... spray application of topical anesthetic above ... offers three endotracheal tubes designs which ...
... ,Designed for neonatal and pediatric patient ... monitoring lumen within the wall of the ... Luer lock connector bonded to lumen line ... monitoring or syringe irrigation of medication., ...
SPIRAL-FLEX® Oral Precut Reinforced Tubes...
Medicine Products: