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Daily 10 milligram dose of S-equol reduces menopausal symptoms effectively without impacting thyroid and sex hormones
Date:6/15/2013

NORTHRIDGE, Calif., June 15, 2013 /PRNewswire-USNewswire/ -- Consuming 10 milligrams (mg) daily of S-equol delivered via a new fermented soy-based nutritional supplement alleviated menopausal symptoms, particularly the frequency of hot flashes and severity of neck or shoulder muscle stiffness, without impacting thyroid and certain sex hormone levels, according to clinical data presented at the annual meeting of The Endocrine Society, (ENDO) 2013.

"This study provides evidence that the daily 10 mg doses of S-equol, a metabolite of the soy isoflavone daidzein, reduced hot flash frequency and relieved muscle stiffness without affecting sex or thyroid hormone levels of Japanese postmenopausal women. The findings confirm and expand on other studies in Japanese and U.S. women documenting the ability of S-equol to help relieve menopausal symptoms," said Belinda H. Jenks, Ph.D., coauthor of the study and director of Scientific Affairs & Nutrition Education at Pharmavite LLC. Development and ongoing research of a supplement containing S-equol is conducted by the Saga Nutraceuticals Research Institute of Otsuka Pharmaceutical Co., Ltd. Pharmavite LLC, the makers of Nature Made® vitamins and minerals, is a subsidiary of Otsuka, which supported the study.

The data presented at ENDO 2013 include results of a dose-finding study and larger confirmation study, both of which were randomized, double-blind and placebo-control trials examining 12 weeks of treatment using a supplement containing S-equol in Japanese postmenopausal women who could not produce S-equol themselves.

S-equol [7-hydroxy-3-(4'-hydroxyphenyl)-chroman] is a compound resulting from the natural metabolism, or conversion, of daidzein, an isoflavone found in whole soybeans. Not everyone can produce S-equol after soy consumption, as the production depends on the types of
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SOURCE Pharmavite LLC
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