Navigation Links
Daiichi Sankyo's Once-Daily Edoxaban Shows Comparable Efficacy and Superiority for the Principal Safety Endpoint Compared to Warfarin in a Phase 3 Study for the Treatment of Symptomatic VTE and Prevention of its Recurrence
Date:8/31/2013

duction in recurrent symptomatic VTE among patients with severe pulmonary embolism who were treated with edoxaban."

"We are excited about the results from the Hokusai-VTE study demonstrating that once-daily edoxaban may provide a new treatment option for a broad range of VTE patients. Daiichi Sankyo plans to submit New Drug Applications for edoxaban for VTE by the first quarter of 2014 in the U.S., Japan and Europe," said Glenn Gormley, MD, PhD, Global Head of Research and Development and Senior Executive Officer, Daiichi Sankyo. "Daiichi Sankyo is committed to continuing the global development of edoxaban and looks forward to the presentation of the results from the phase 3 ENGAGE AF-TIMI 48 study in patients with atrial fibrillation at the 2013 American Heart Association Scientific Sessions in November."

About Hokusai-VTE

Hokusai-VTE was a global, event-driven, randomized, double-blind, parallel-group phase 3 clinical study involving 8,292 patients in 439 clinical sites across 37 countries to evaluate once-daily edoxaban in patients with symptomatic DVT and/or PE.1

Patients were randomized to one of two different treatment groups. Both groups received open-label enoxaparin or unfractionated heparin for at least five days, and either warfarin or placebo (administered to edoxaban group), followed by double-blind edoxaban 60 mg (n=4,118) (edoxaban 30 mg for patients with renal impairment or low body weight or p-glycoprotein inhibitor use) or warfarin (n=4,122) for at least three months and up to a maximum of one year (duration of study treatment was determined by the investigator based on the patient's clinical features). Patients were followed for 12 months regardless of treatment duration to provide investigators with a better understanding of outcomes in clinical practice relative to an on-treatment analysis only.1

The primar
'/>"/>

SOURCE Daiichi Sankyo Company, Limited
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Daiichi Sankyo, Inc. Receives FDA Approval to Package Product at New Facility in Bethlehem, PA
2. Daiichi Sankyo Completes Enrolment in Hokusai - VTE, investigating once-daily Edoxaban in the Largest Single Phase 3 Study for the Treatment and Prevention of Recurrence of VTE
3. Daiichi Sankyo ha completato larruolamento dei pazienti per lo studio Hokusai-VTE su Edoxaban, il più ampio trial clinico di fase 3 per il trattamento delle tromboembolie venose ricorrenti
4. Daiichi Sankyo CEO John Gargiulo Elected as National Pharmaceutical Councils Chairman of the Board
5. Sosei Group Corporation: Data at ERS Shows Efficacy of Once-daily COPD Portfolio Versus Comparators, Further Establishes Dual-bronchodilator QVA149
6. Sosei Group Corporation: QVA149 Filed as a Once-Daily Maintenance Treatment for COPD in Europe
7. Sosei Group Corporation: QVA149 Filed by Licensing Partner as a Once-Daily Maintenance Treatment for COPD in Japan
8. Upsher-Smith Presents Data Supporting Favorable Tolerability And Consistent Pharmacokinetic Profile Of Once-Daily USL255 (Extended-Release Topiramate)
9. Sanofi Announces Positive Phase 3 Data for Once-Daily Lixisenatide for Type 2 Diabetes
10. Clinical Trial at Evergreen Healthcare Shows Intestinal Gel Reduces Symptoms of Advanced Parkinsons Disease
11. Structural Trends to Profoundly Change Life Sciences Industry, Genpact Study Shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... , July 22, 2014 ... Research "Process Spectroscopy Market (Technology Types - Near infrared (NIR) ... - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, ... million in 2012 and is expected to grow at a ... North America was the largest contributor to ...
(Date:7/22/2014)... July 22, 2014 The number of people ... people each day. Twenty-three percent of the workforce has ... Drug Use and Health, making opioid use a serious ... opioid painkillers at the correct dosage with a valid ... Today, the National Safety Council released a ...
(Date:7/22/2014)... 2014 BiologicTx ® today announced their ... Kidney Paired Donation transplant exchange utilizing BiologicTx,s proprietary matching ... 9 at the Miami Transplant Institute, located at Jackson ... Kidney Paired Donation (KPD) is an ... kidney transplant with one another due to incompatible blood ...
Breaking Medicine Technology:Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 2Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 3Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 45 things employers should know about prescription painkiller use 25 things employers should know about prescription painkiller use 3BiologicTx Paired Donation Aids In Successful Kidney Transplants 2BiologicTx Paired Donation Aids In Successful Kidney Transplants 3
... March 14, 2011 Streamline Health Solutions, Inc. (Nasdaq: ... document workflow solutions for hospitals, announced today that Rick ... Marketing Officer effective March 14, 2011. With more than ... to Streamline Health an extensive background in developing and ...
... the animal health division of Eli Lilly and Company ... has made an irrevocable, unconditional offer to acquire the ... & Johnson Company. The two companies have notified the ... Beerse, Belgium, Janssen,s animal health business is primarily European-focused, ...
Cached Medicine Technology:Streamline Health Appoints Rick Leach as Senior Vice President and Chief Marketing Officer 2Streamline Health Appoints Rick Leach as Senior Vice President and Chief Marketing Officer 3Streamline Health Appoints Rick Leach as Senior Vice President and Chief Marketing Officer 4Lilly Makes an Irrevocable Offer to Acquire Janssen Animal Health 2Lilly Makes an Irrevocable Offer to Acquire Janssen Animal Health 3
(Date:7/23/2014)... (PRWEB) July 23, 2014 In an ... Plan to Address Alzheimer’s Disease” at the state level, ... the Alzheimer’s Foundation of America (AFA) this ... of the Alzheimer’s crisis, and the need for wide-scale ... to those localities. , The white paper ...
(Date:7/23/2014)... --- Controlling pain during childbirth and post delivery may ... M.D., a Northwestern Medicine perinatal psychiatrist, in a July ... , Wisner,s editorial is based on a new Chinese ... epidural anesthesia during a vaginal delivery had a much ... have the epidural. , "Maximizing pain control in labor ...
(Date:7/22/2014)... 2014 Ticket Down is a ... City tickets at Sporting Park in Kansas City, MO. ... July 23rd. Tickets can be conveniently printed out for ... Down can be reached toll free at 1-877-870-3653. All ... and covered by Ticket Down's customer satisfaction guarantee. , About ...
(Date:7/22/2014)... Francisco, CA (PRWEB) July 22, 2014 ... producing products for consumers to buy can now reduce ... Cherry News company has released its cosmetic buying guide ... under eyes at http://cherrynews.com/best-nourishing-eye-serum . , This guide ... who suffer from the different under eye circles that ...
(Date:7/22/2014)... 22, 2014 DocbookMD , a ... deploying one of the largest physician-centric mobile communication solutions ... ) in Houston. , Created by Austin-based physicians, Tracey ... application will be embedded into MHMD’s Accountable Care Network ... the best technology to put this capability at the ...
Breaking Medicine News(10 mins):Health News:National Alliance for Caregiving and Alzheimer’s Foundation of America Release Joint Report to Help States Implement Alzheimer’s Plans 2Health News:National Alliance for Caregiving and Alzheimer’s Foundation of America Release Joint Report to Help States Implement Alzheimer’s Plans 3Health News:Controlling childbirth pain tied to lower depression risk 2Health News:Sporting Kansas City vs. Manchester City Tickets: Ticket Down Has Slashed Ticket Prices for Manchester City vs. Sporting Kansas City on July 23rd 2Health News:Remove Dark Circles Under Eyes: New Cosmetic Buying Guide Released Online for Men and Women 2Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 2Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 3Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 4
... FRANCISCO, May 11 Today,s announcement takes shared responsibility ... are committing to share responsibility for saving $2 trillion ... they succeed, affordable coverage for all is within our ... coverage based on universal responsibility. We are pleased ...
... a change of pace for cardiac rehab programs, , , MONDAY, ... who are overweight, longer but slower walks are better for ... a new study has found. , Frequent long, slow walks ... moderate pace, five to six days a week -- were ...
... United States Agency for International Development (USAID) announced today ... activities in Kenya would rise to $17.8 million in ... to USAID,s family planning and reproductive health activities in ... the Government of Kenya,s efforts to increase access to ...
... The Texas Cardiac Arrhythmia Institute (TCAI) at St. David,s ... heart rhythm disorders since it launched on May 1, ... Central Texas."In just one year, the physician team at ... Center, coupled with our unmatched level of technology, has ...
... Thermofocus(R) 5-in-1WESTON, Fla., May 11 American Scientific Resources, ... for the first quarter ending March 31, 2009. ... sales of $263,603 for the first quarter of 2009, ... first quarter of 2008.The sales increase was predominantly due ...
... 11 /PRNewswire-Asia-FirstCall/ -- Jiangbo,Pharmaceuticals, Inc. (OTC Bulletin Board: GNPH) ... in the People,s Republic,of China, today announced that its ... Board under the new ticker symbol "JGBO" as of ... the ticker symbol "GNPH" at the,end of May 11, ...
Cached Medicine News:Health News:Walk Long, Slow and Often to Help the Heart 2Health News:Walk Long, Slow and Often to Help the Heart 3Health News:U.S. Increases Funding for Kenya's Family Planning and Reproductive Health Activities 2Health News:Texas Cardiac Arrhythmia Institute at St. David's Medical Center Celebrates Successful First Year 2Health News:Texas Cardiac Arrhythmia Institute at St. David's Medical Center Celebrates Successful First Year 3Health News:Texas Cardiac Arrhythmia Institute at St. David's Medical Center Celebrates Successful First Year 4Health News:American Scientific Resources, Inc. Releases First Quarter Revenues 2Health News:Jiangbo Pharmaceuticals Announces New Ticker (JGBO) and CUSIP 2
... patient ID verification and laboratory specimen labeling system ... the phlebotomist or nurse, the identity of the ... verification is made, a bar coded sample ID ... unique design simplifies and eliminates the interface problems ...
... Horizon Admin-Rx is a bar-code medication administration ... medication administration process with bar-code technology. Caregivers ... handheld or laptop device to verify that ... at the right time in the right ...
... MedPoint™, a Medication Administration Control ... positive assurance that they are administering ... When used with a bar coded ... MedPoint extends the benefits of the ...
... When it comes to medication administration, ... afford to make. The solution is the ... a highly-scalable bar-coded medication administration system, suitable ... also be used stand-alone, networked, or as ...
Medicine Products: