Navigation Links
Daiichi Sankyo Initiates Largest Single, Double-Blind, Randomized, Phase III Trial for Treatment and Prevention of Recurrent Venous Thromboembolism
Date:2/3/2010

TOKYO and EDISON, N.J., Feb. 3 /PRNewswire/ -- Daiichi Sankyo Company, Limited (TSE: 4568), announced today that it has initiated a new large-scale pivotal Phase III trial for edoxaban, its investigational oral Factor Xa inhibitor. This new study, called HOKUSAI (pronounced hoe·koo·sigh) VTE, is evaluating the safety and efficacy of edoxaban in reducing recurrent venous thromboembolic (VTE) complications in patients with deep vein thrombosis (DVT) and/or pulmonary embolism (PE).

It is estimated that more than 900,000 fatal and non-fatal VTE events occur in the U.S. annually, and approximately 300,000 deaths are related to VTE per year.(i)  In Europe, VTE affects more than 750,000 people in six major European countries (France, Germany, Italy, Spain, Sweden, UK) annually, and approximately 370,000 deaths are related to VTE per year in these countries.(ii)

"The incidence of VTE is predicted to double by 2050,(iii)" said Harry R. Buller, M.D., Professor of Internal Medicine, chairman of the Department for Vascular Medicine at the Academic Medical Center, Amsterdam and chairman of the Steering Committee for HOKUSAI VTE.  "Based on what we've seen in Phase II and other trials, edoxaban shows promise as an agent to help fulfill the need for treatment options that are safe, effective and more convenient than the current standard of care, which requires extensive monitoring, careful dose adjusting and may have the potential for various drug and food interactions."

The primary efficacy endpoint for HOKUSAI VTE is the recurrence of symptomatic VTE (i.e., the composite of D
'/>"/>

SOURCE Daiichi Sankyo
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Daiichi Sankyo Initiates Phase III Trial of Its Investigational Factor Xa Inhibitor, DU-176b, in Patients With Atrial Fibrillation
2. Daiichi Sankyo and Lilly Respond to Speculation on Status of Prasugrel New Drug Application
3. Daiichi Sankyo Announces Clinical Study Data for Oral Factor Xa Inhibitor DU-176b
4. FDA Extends Review Period for Daiichi Sankyo, Lilly Investigative Antiplatelet Drug, Prasugrel
5. Daiichi Sankyo/Eli Lillys Effient and Astrazenecas Ticagrelor May Offer Advantages in the Treatment of Post-Myocardial Infarction
6. FDA Grants Priority Review for Daiichi Sankyo, Lilly Drug, prasugrel
7. Daiichi Sankyo and Forest Laboratories Finalize Contract for Co-Promotion of AZOR(TM)
8. Celsis Initiates Patent Infringement Action Against XenoTech and Sekisui
9. Romark Initiates Clinical Trial of Alinia for Treatment of Influenza
10. Conatus Pharmaceuticals Initiates Phase II Clinical Trial in Combination With Pegylated Interferon and Ribavirin for the Treatment of Hepatitis C Virus (HCV)
11. ChemoCentryx Initiates Clinical Trial of CCX168, A Novel Small Molecule C5aR Antagonist for the Treatment of Inflammatory and Autoimmune Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Pharma IQ, after huge demand ... Countdown calendar to cover the years 2014 - 2018 ... shows the serialisation requirements around the globe and the ... For companies dealing with international markets, serialisation ... they will have to comply with new regulations coming ...
(Date:9/18/2014)... 2014   3D Systems   (NYSE: DDD ... Mentor™ , a new robotic surgery skills and procedural training ... the ERUS exhibition in Amsterdam, The Netherlands ... Robotic-assisted minimally invasive surgery represents a growing portion of overall ... training for robotic surgery has increased, and it is expected ...
(Date:9/18/2014)... 2014 After 6 months of careful ... here - the new programme for the next Cool Chain ... our global Cool Chain series, has just been released! ... As the lines between supply chain, logistics, QA and ... that is broad and yet specific, focused and yet accessible, ...
Breaking Medicine Technology:Pharma IQ Displays Worldwide Serialisation Deadlines in their 2014 - 2018 Countdown Calendar 23D Systems Introduces New Simbionix Robotics Training Platform 23D Systems Introduces New Simbionix Robotics Training Platform 3Europe's Biggest and Longest-Running Gathering of Life Sciences Logistics, Supply Chain & QA Professionals 2
... , WASHINGTON, Nov. 24 ... and vaccines to treat or prevent HIV/AIDS and related conditions, according ... Manufacturers of America (PhRMA). December 1 marks the 21st anniversary of ... the 1988 World Summit of Ministers of Health on Programmes for ...
... , NORTH HOLLYWOOD, Calif., Nov. 24 ... national hospitalist physician group practice company, announced today that Philip Vaidyan, ... as one of the 2009 Top Ten Hospitalists in the ... magazine. , Dr. Vaidyan has been a practicing physician for more ...
Cached Medicine Technology:New Report Shows 97 Medicines and Vaccines Currently in Development for HIV/AIDS 2New Report Shows 97 Medicines and Vaccines Currently in Development for HIV/AIDS 3IPC The Hospitalist Company's Philip Vaidyan, M.D. Named a Top Hospitalist of 2009 2IPC The Hospitalist Company's Philip Vaidyan, M.D. Named a Top Hospitalist of 2009 3
(Date:9/18/2014)... Ben Quirk, CEO of Quirk Healthcare ... Award by the Savannah Science Seminar in recognition for ... the nation and especially in Savannah. , “I am ... “The Savannah Science Seminar is an amazing program that ... have gone through the program,” he added. Eleventh graders ...
(Date:9/18/2014)... microbes -- don,t worry, it,s a good thing! As ... microbes are bad. Many active enzymes and bacteria are ... as an important part of our digestive system or ... albicans , an opportunistic yeast pathogen and model organism ... healthy personal ecosystem. However, when our immune system is ...
(Date:9/18/2014)... one-day conference at the Milken Institute School of Public ... 2014 to discuss the Global Health Security Agenda (GHSA) ... this event is to invite discussion of proposed priorities ... action plans to curtail the current deadly Ebola outbreak. ... organizations and more than 50 countries have engaged in ...
(Date:9/18/2014)... (September 18, 2014) The National Institutes of Health ... a four-year, $1.3 million grant to the Los Angeles ... research and development of a vaccine to protect patients ... Staphylococcus aureus (MRSA). , The National ... NIH awarded the grant to LA BioMed infectious disease ...
(Date:9/18/2014)... such as the Ebola virus invoke scary scenarios of ... bubonic plague are still providing researchers with new insights ... a study published online Sept. 18, 2014, in the ... Duke-NUS Graduate Medical School Singapore detail how the Yersinia ... cells in the lymph nodes and eventually ride into ...
Breaking Medicine News(10 mins):Health News:Quirk Awarded the Alex Ormond, Jr. Leadership Award by the Savannah Science Seminar 2Health News:Everything in moderation: Micro-8 to study regulating pathogens in space 2Health News:Everything in moderation: Micro-8 to study regulating pathogens in space 3Health News:Non-governmental stakeholders to discuss the Global Health Security Agenda 2Health News:LA BioMed receives NIH grant to study vaccine for hospital-acquired infections 2Health News:New insights on an ancient plague could improve treatments for infections 2
... ... follow-up. This study appears in Plastic and Reconstructive Surgery, the offical medical journal of the ... ... aesthetic procedures in the world for excess fat removal - and while its relative safety ...
... early intervention can help , MONDAY, March 1 (HealthDay ... between depression and obesity, say researchers who reviewed the ... , "We found bidirectional associations between depression and obesity: ... developing depression over time, whereas depressed persons had a ...
... ill with cancer from further pain prompts feelings, survey finds ... child die of cancer is unimaginably heartbreaking for parents, and ... terminally ill children from any further pain led one in ... from the Dana-Farber Cancer Institute in Boston asked 141 parents ...
... ... joined forces with Upside Group Franchise Consulting to expand their franchise base. ... retailer of conventional bedding and sleep related products. Upside Group Franchise ... the country. In the coming decade, the sleep industry is ...
... ... ... ... ...
... ... ... ... ...
Cached Medicine News:Health News:New Study Tunes Into Latest Lipo Technique 2Health News:Obesity and Depression: A Vicious Circle? 2Health News:Some Parents Consider Hastening a Sick Child's Death 2Health News:Some Parents Consider Hastening a Sick Child's Death 3Health News:Some Parents Consider Hastening a Sick Child's Death 4Health News:Mattress Firm Partners with Upside Group Franchise Consulting 2Health News:National Study Reports Staggering Spending Increases Among Seniors With Chronic Conditions Through Original Medicare - Special Needs Plan Program Offers Solution For Those In Texas 2Health News:National Study Reports Staggering Spending Increases Among Seniors With Chronic Conditions Through Original Medicare - Special Needs Plan Program Offers Solution For Those In Texas 3Health News:National Study Reports Staggering Spending Increases Among Seniors With Chronic Conditions Through Original Medicare - Special Needs Plan Program Offers Solution For Those In Texas 4Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 2Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 3Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 4Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 5Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 6
For the qualitative detection of human Chorionic Gonadotrophin (HCG) in urine or urine and serum specimens...
ZyDoc offers a full medical transcription and documentation solution....
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
Medicine Products: