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DURECT Announces ELADUR® (TRANSDUR®-Bupivacaine) Phase II Study Results in Chronic Low Back Pain
Date:4/11/2011

ood and Drug Administration or other health authorities.

DURECT Forward-Looking Statement

The statements in this press release regarding ELADUR, including its potential uses and benefits, future development activities and the potential milestone payments and royalties receivable from our agreement with Pfizer (Alpharma) are forward-looking statements involving risks and uncertainties that can cause actual results to differ materially from those in such forward-looking statements.  Potential risks and uncertainties include, but are not limited to, the possible failure to demonstrate efficacy in future clinical trials, potential side effects or adverse events observed during clinical trials,  possible delays and costs due to additional work or other requirements imposed by regulatory agencies for continued development, approval or sale of ELADUR, possible commercial challenges including competition from other products, difficulty in gaining reimbursement and generic competition, and the possible impact of these factors on Pfizer's interest in developing or commercializing ELADUR. Further information regarding these and other risks is included in DURECT's Form 10-K filed on March 3, 2011 under the heading "Risk Factors."


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