Navigation Links
DOV 21,947 Demonstrates Significant Body Weight and BMI Reductions in Drug- Compliant Subjects in Phase Ib Clinical Study
Date:9/25/2007

"There is a significant co-morbidity of obesity with major depressive disorder that can be exacerbated by the weight gain produced by many antidepressants. We believe a product that could not only manage depression but also impact weight gain would represent a significant advantage over currently marketed antidepressants. Because this study did not include dietary restrictions, exercise programs, and other weight management tools that are often incorporated in obesity trials, it is remarkable that DOV 21,947 produced a robust reduction in body weight compared to placebo. These data not only validate our preclinical findings with DOV 21,947, but also provide a clear differentiator that we will explore in further development. In addition, this data serves to validate the therapeutic versatility of this class of compounds," said Dr. Phil Skolnick, President and Chief Scientific Officer of DOV.

"The delay in the initiation of the Phase II study of DOV 21,947 to the first quarter of 2008 has enabled us to further evaluate the protocol design to ensure that we are capturing potential effects of DOV 21,947's effects on body weight and appropriately capture drug-compliance in our analyses. This delay, along with other cost containment measures, also serves to provide us with sufficient capital through April 2008 as we explore our financing and collaborative options," said Barbara Duncan, Chief Executive Officer of DOV. The double-blind, Phase II study now scheduled for initiation in the first quarter of 2008 will compare up to 100 mg per day of DOV 21,947 versus placebo in approximately 200 patients with major depressive disorder over a six-week treatment period. The Company expects the results from this Phase II study to be available at the end of 2008.

About DOV 21,947

Clinical research indicates that co-administrating drugs that, in combination, inhibit reuptake of the three neurotransmitters most closely linked to depression - serotonin, norepinephr
'/>"/>

SOURCE DOV Pharmaceutical, Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. The International Myeloma Foundation Says Data Reported at a Global Medical Meeting in Greece Demonstrates Improved Survival for a Wide Range of Myeloma Patients
2. Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone
3. New Research Demonstrates Broad Efficacy of Azixa (MPC-6827) Against Multiple Tumor Types and in Drug Resistant Cell Lines
4. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
5. Gerons Telomerase Inhibitor Cancer Drug Demonstrates Good Pharmacokinetics and Tolerability in Phase I/II Trial
6. Frova Phase III Study Data Demonstrates That Short-Term Prevention Treatment Reduces Frequency and Severity of Menstrual Migraine
7. Mymetics HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model
8. Cipralex demonstrates superiority to duloxetine for acute treatment of depression in new study
9. Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression
10. Introgens Advexin Demonstrates Clinical Benefit in Inherited Cancer
11. Prostate Cancer: Clinical Study Demonstrates Superior Efficacy of Docetaxel Chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... PHILADELPHIA , May 17, 2013 ... disorders; health economics and outcomes research also   to ... SHP, NASDAQ: SHPG ), the global specialty ... in 7 poster presentations at the American Psychiatric Association ... , May 18-22. The data being presented represent ...
(Date:5/17/2013)... May 17, 2013  Serving a region of 650,000 inhabitants ... , Caribbean Imaging and Radiation Therapy (CIRT, Ponce ... with the acquisition of an Elekta Versa HD™ system, the ... offers clinicians the versatility to deliver conventional therapies to treat ... enabling treatment of highly complex cancers that require extreme targeting ...
(Date:5/17/2013)... SEATTLE , May 17, 2013  Atossa Genetics, Inc. ... today that Kyle Guse , Chief Financial ... Marcum LLP MicroCap Conference on Thursday, May 30, 2013, in ... Hyatt Hotel. The Company,s presentation is scheduled ... via a live webcast. To access the webcast, go to ...
Breaking Medicine Technology:Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 2Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 3Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 4Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 5Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 6Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 7Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 8Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 9Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting 10Puerto Rico's Caribbean Imaging and Radiation Therapy Center Orders Elekta's New Versa HD System for Treatment of Cancer Patients 2Atossa Genetics to Present at the Second Annual Marcum LLP MicroCap Conference 2Atossa Genetics to Present at the Second Annual Marcum LLP MicroCap Conference 3
... Infection Prevention Business, DUBLIN, Ohio, May 12 ... services that improve the safety and,productivity of health ... assets of privately held Enturia, Inc., the manufacturer ... name., ChloraPrep(R) brand products are used widely ...
... Inc. (OTC,Bulletin Board: GOVX), an Atlanta- based HIV/AIDS ... into a $10 million common,stock purchase agreement with ... The Company may sell up to $10 ... time to time over a 25-month period after ...
Cached Medicine Technology:Cardinal Health Completes Enturia Acquisition 2GeoVax Secures $10 Million Financing Commitment 2GeoVax Secures $10 Million Financing Commitment 3
(Date:5/19/2013)... Seven-year-old Torin Phillips and his 6-year-old sister, ... effects of autism. The two siblings, who live just ... behavior therapy (ABA) from the Center for Autism ... most effective treatment centers using evidence-based, state-of-the-art therapy. , ... or answer to his name, and had little interest ...
(Date:5/19/2013)... (PRWEB) May 19, 2013 At ... National Council of Asian Pacific Physicians (NCAPIP), the ... the National Association of Chronic Disease Directors (NACDD), ... of health systems, diabetes, and non-communicable diseases (NCDs) ... The assessment, published in the Hawaii Journal of ...
(Date:5/19/2013)... PHILADELPHIA ─ Gourmands and foodies everywhere have long recognized ... peppery zing to both sweet and savory dishes; now, ... components of the spicy root also may have properties ... results of the study will be presented at the ... bronchoconstriction, a tightening of the bronchial tubes that carry ...
(Date:5/19/2013)... Minnesota (PRWEB) May 19, 2013 People in ... the summer. Altman Fitness is offering its 28 Day Fat ... the program from the comfort of their own home. The ... upon purchase. More information can be accessed here: http://altmanfitness.com/28-day-fat-loss-formula/ ... want to leave their houses now, but after using the ...
(Date:5/19/2013)... 2013 Today, Zane Benefits, Inc. ... health insurance . Zane Benefits, which provides comprehensive ... benefits, is the leader in health care reform, ... arrangements . , According to Zane Benefits’ website, ... know the value of small business health insurance ...
Breaking Medicine News(10 mins):Health News:Boston Brother and Sister Battle Odds to Overcome Autism with Help from Center for Autism and Related Disorders 2Health News:Boston Brother and Sister Battle Odds to Overcome Autism with Help from Center for Autism and Related Disorders 3Health News:Boston Brother and Sister Battle Odds to Overcome Autism with Help from Center for Autism and Related Disorders 4Health News:Pacific Island Public Health Group Declares Diabetes at Pandemic Proportions 2Health News:Pacific Island Public Health Group Declares Diabetes at Pandemic Proportions 3Health News:Ginger compounds may be effective in treating asthma symptoms 2Health News:Zane Benefits Publishes New Information on Small Business Health Insurance 2Health News:Zane Benefits Publishes New Information on Small Business Health Insurance 3
... medical officer; Pam Lux vice president of internal and ... health management , EAGAN, Minn., Oct. 12 ... announces three new leaders at the organization. Gregory Gilmet, ... Lux is vice president of internal and external communications, ...
... understanding can occur 3 years before diagnosis, study finds ... to perceive relationships between objects (visuospatial skills) may decline ... a new study suggests. , It included 444 people ... study and underwent tests on a number of cognitive ...
... CDPHP announced ... Warren, and Essex - to complement its growing service area. Medicare beneficiaries in these counties ... , ... October 12, 2009 -- CDPHP announced the expansion of its Medicare Choices ...
... Iowa, Oct. 12 The Iowa Committee for Value ... principles for high-value, fiscally responsible health care that Congress ... discussions over national reform. , The committee found that ... of the principles for value-based reform. Health care providers, ...
... kicking nicotine addiction , MONDAY, Oct. 12 (HealthDay News) -- ... million grant to a Maryland company to help it in ... , Nabi Biopharmaceuticals of Rockville will launch a phase ... which could be the last step of research if the ...
... ... Trends , ... WA (Vocus) October 12, 2009, , ,MEDIA ALERT, , ,WHO: More than 5,000 ... , , ,WHAT: Plastic Surgery 2009, the American Society of Plastic Surgeons (ASPS) ...
Cached Medicine News:Health News:Blue Cross Names Three New Executives 2Health News:Blue Cross Names Three New Executives 3Health News:Drop in Certain Visual Skills May Precede Alzheimer's 2Health News:CDPHP Medicare Choices Expands Service Area Northward 2Health News:CDPHP Medicare Choices Expands Service Area Northward 3Health News:Iowa Committee Makes Recommendations to Increase Value in Health Care 2Health News:Iowa Committee Makes Recommendations to Increase Value in Health Care 3Health News:Iowa Committee Makes Recommendations to Increase Value in Health Care 4Health News:Iowa Committee Makes Recommendations to Increase Value in Health Care 5Health News:Stop-Smoking Vaccine in the Works 2Health News:American Society of Plastic Surgeons Annual Meeting Photo Op 2Health News:American Society of Plastic Surgeons Annual Meeting Photo Op 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: