Navigation Links
DNAtrix, Inc. to Present Clinical Study Results for DNX-2401 (Delta 24-RGD), A Conditionally Replication-Competent Adenovirus
Date:6/17/2013

HOUSTON, June 17, 2013 /PRNewswire/ -- DNAtrix Inc., experts in oncolytic virus development, today announced that its CEO will present clinical data on the company's lead product, DNX-2401, at the Replicating Oncolytic Virus Therapeutic meeting in Quebec City, Canada on June 18, 2013.

Dr. Frank Tufaro, DNAtrix's CEO and a leader in the field of oncolytic virus therapy, will present results from a clinical study entitled A PHASE I TRIAL OF A CONDITIONALLY REPLICATION-COMPETENT ADENOVIRUS DNX-2401 (FORMERLY KNOWN AS DELTA-24-RGD) FOR RECURRENT MALIGNANT GLIOMAS that evaluated DNX-2401 for patients diagnosed with recurrent glioblastoma. Dr. Tufaro will present study data indicating that DNX-2401 has been well tolerated in 37 patients with no dose-limiting toxicity. Additionally, DNX-2401 has demonstrated highly impressive activity and efficacy.

"We are extremely pleased to have participated in bringing DNX-2401 into the clinic, and are encouraged by the results from this clinical study," said Dr. Tufaro. "DNX-2401 has not only revealed a positive safety profile but also an ability to selectively kill glioblastoma cells. This is exciting because it can lead to complete tumor destruction."

About Glioblastoma and DNX-2401
Glioblastoma is a devastating primary brain tumor resistant to conventional therapies and the second most common cause of death from intracranial disease. The lack of effective therapy for brain tumors has led to intense investigations of novel therapeutic approaches that use vectors and recombinant viruses. Oncolytic virus therapy is based on the concept of using live viruses to selectively infect and replicate in cancer cells, with minimal destruction of normal tissue. Replication amplifies the input dose of the oncolytic virus and helps spread the agent to adjacent tumor cells. DNX-2401, a conditionally replication-competent adenovirus, is being developed for the treatment of several cancer indications including patients with recurrent glioblastoma. DNX-2401 is the culmination of more than a decade of scientific and clinical research and is the most potent and effective oncolytic virus delivered to human brain tumors to date.  DNAtrix will initiate a Phase II clinical study later this year.

About DNAtrix, Inc.
DNAtrix is a company developing modified viruses for the treatment of the most aggressive forms of cancer. Since viruses are already efficient at killing cells, scientists have harnessed this ability by modifying a common cold virus so that it targets and selectively kills cancer cells. DNAtrix is a privately held company located in Houston, Texas and San Diego, California. For more information, please visit the Company's website at http://www.dnatrix.com.

DNAtrix, Inc. Contact
Frank Tufaro, Ph.D.
Chief Executive Officer
ftufaro@dnatrix.com
(858) 342-6577


'/>"/>
SOURCE DNAtrix, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Report Presents a Framework for Successful New Oncology Product Launches in the Pharmaceutical Sector
2. Latest Findings in Breastfeeding Science Presented at Medelas 7th International Breastfeeding and Lactation Symposium
3. Auxilium Pharmaceuticals to Present at the Deutsche Bank 37th Annual Healthcare Conference
4. Enox Biopharma, Inc. To Present Today At IN3 Medical Device 360 Conference In London
5. Foundation for Managed Care Pharmacy (FMCP) Presents Awards for 2012 National P&T Competition and Best Posters
6. Neurocrine Biosciences Announces Conference Call and Webcast to Present First Quarter 2012 Financial Results
7. Interim results of VITOBA™ (VImpaT® added to One Baseline AED) Study Presented at the 64th Annual Meeting of the American Academy of Neurology
8. Hospira to Present at the Bank of America Merrill Lynch 2012 Health Care Conference
9. Ultra Clean to Present at the Jefferies 2012 Global Technology, Media & Telcom Conference
10. Anlit to Present New Dietary Supplements for Children at Vitafoods Europe 2012
11. Avanir Pharmaceuticals To Present at Three Conferences In May
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... 2017 The U.S. Food and Drug Administration today ... (CIC) in adult patients. "No one medication ... Julie Beitz , M.D., director of the Office of ... and Research. "With the availability of new therapies, patients and ... condition." ...
(Date:1/19/2017)... CITY, N.J. , Jan. 19, 2017 ... over $100 for their medication when a pharmacy just ... same exact prescription.  To alleviate this problem Medicationdiscountcard.com ... and patients to see exactly how much their medication ... Comparison Shopping Made Easy ...
(Date:1/19/2017)... 19, 2017 Accuray Incorporated (Nasdaq: ... Systems continue to set the bar for excellence in ... overall user satisfaction rating among radiation treatment delivery systems ... Buyline Market Intelligence Briefing™. The most recent ratings trend ... among industry peers for 11 of the past 12 ...
Breaking Medicine Technology:
(Date:1/20/2017)... , ... January 20, 2017 , ... Lice Troopers, the ... cases in families with school-aged children since the holiday season. , “It happens ... with their families, sharing hugs and taking photos, which is the head-to-head gateway that ...
(Date:1/20/2017)... ... January 20, 2017 , ... "TransFlare 4K Mystique comes ... of Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Utilizing the Dragon Sensor,TransFlare 4K Mystique lens flare and light leak transitions have a ...
(Date:1/20/2017)... ... ... Biscuit”: a biographical account following a man who went on to support his country and ... born in Lynn Haven, Florida and at the age of 5, his family moved to ... joined the Navy and got married right out of boot camp. , He and ...
(Date:1/20/2017)... , ... January 20, 2017 , ... “Journey to Christmas:” a beautiful and enchanting tale ... published author, Kimberly Cordoves, a mother of three in Oklahoma City, and a devoted woman ... of writing a book has been in the back of my mind for years, but ...
(Date:1/19/2017)... ... , ... Today, the Centers for Medicare & Medicaid Services (CMS) announced over ... (APMs) in 2017. Clinicians who participate in APMs are paid for the quality of ... Administration’s effort to build a system that delivers better care and one in which ...
Breaking Medicine News(10 mins):