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DNA Vaccine Developed at the Karmanos Cancer Institute Fights HER2-Positive Cancers
Date:9/14/2008

with the Karolinska Institute in Stockholm, Sweden, a pilot clinical trial with the HER2 DNA vaccine has been conducted in patients with Stage IV breast cancer and has demonstrated safety. Further testing is being considered.

Dr. Wei added, "As we continue our extensive research on this promising vaccine, based on the results to-date, we believe this could eventually help control the spread of HER2-positive breast cancer in patients who have been resistant to other treatments, and possibly prevent HER2-positive breast cancer from occurring."

Other researchers working with Dr. Wei include: Paula J. Whittington, Marie P. Piechocki, Henry H. Heng, Jennifer B. Jacob, Richard F. Jones and Jessica B. Back.

Located in mid-town Detroit, MI, the Barbara Ann Karmanos Cancer Institute is one of 41 National Cancer Institute-designated comprehensive cancer centers in the United States. Caring for more than 6,000 new patients annually on a budget of $216 million, conducting more than 700 cancer-specific scientific investigation programs and clinical trials, the Karmanos Cancer Institute is among the nation's best cancer centers. Through the commitment of 1,000 staff, including nearly 300 faculty members, and supported by thousands of volunteer and financial donors, the Institute strives to prevent, detect and eradicate all forms of cancer. John C. Ruckdeschel, M.D., is the Institute's president and chief executive officer. For more information call 1-800-KARMANOS or go to http://www.karmanos.org.


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SOURCE Barbara Ann Karmanos Cancer Institute
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