Navigation Links
DIFICID™ Demonstrated Early Superiority in the First 12 Days Compared to Vancomycin in New Analysis of Phase 3 Study Results
Date:10/20/2011

SAN DIEGO, Oct. 20, 2011 /PRNewswire/ -- Optimer Pharmaceuticals, Inc. (Nasdaq: OPTR) announced today that data being presented at the 49th Annual Meeting of the Infectious Diseases Society of America (IDSA) demonstrate that patients treated with DIFICID™ (fidaxomicin) tablets for Clostridium difficile-associated diarrhea (CDAD) experienced faster resolution of diarrhea and lower risk of death during the first 12 days following initiation of treatment compared to patients treated with vancomycin. The retrospective analysis of results from two large, multi-national Phase 3 clinical studies, which assessed the efficacy of DIFICID versus vancomycin for the treatment of CDAD in adults, was completed by researchers from the National Institute for Health Research (NIHR) Biomedical Research Centre, Oxford,  a research partnership between the Oxford Radcliffe Hospitals and the University of Oxford.

(Logo:  http://photos.prnewswire.com/prnh/20090413/LA97352LOGO)

In the analysis, patients treated with DIFICID experienced a 37% reduction in persistent diarrhea or death through day 12 of the study (95% CI: 2-60%; p=0.037) compared to those treated with vancomycin. These data are among those featured in a late-breaking poster presentation at the IDSA annual meeting being held in Boston from October 20-23.

"We were encouraged by the results of the Phase 3 clinical studies and believed that a more comprehensive look at the patient characteristics of the Phase 3 study participants might yield even greater insights into the use of DIFICID for the treatment of CDAD," said Sarah Walker, PhD, Senior Statistician at the NIHR Biomedical Research Centre, Oxford, and the primary author of the analysis. "In our analysis, we found that DIFICID not only reduced persistent diarrhea and early death
'/>"/>

SOURCE Optimer Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Optimer Pharmaceuticals and Astellas Receive Positive Opinion from CHMP for European Approval of DIFICID™
2. Optimer to Provide DIFICID™ Launch Update at Morgan Stanley Global Healthcare Conference
3. Clinical Infectious Diseases Publishes Subgroup Analysis Showing Optimers DIFICID™ (fidaxomicin) Tablets Exhibited Higher Clinical Cure and Global Cure Rates Than Vancomycin in Patients with Clostridium difficile-Associated Diarrhea (CDAD) Receivin
4. Optimer Launches DIFICID™ (fidaxomicin) Tablets for Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) in Patients 18 Years of Age and Older
5. Data Presented at Digestive Disease Week Highlights Additional Analysis of DIFICID™ Phase 3 Data
6. Optimer Pharmaceuticals and Cubist Pharmaceuticals Announce Collaboration to Co-Promote DIFICID™ (Fidaxomicin) for Clostridium difficile Infection in the United States
7. Optimer Announces that the U.S. Food and Drug Administrations Anti-Infective Drugs Advisory Committee Voted Unanimously to Recommend Approval of Novel Antibiotic Dificid™ for Treatment of Patients with Clostridium difficile infection (CDI)
8. New Study Published in New England Journal of Medicine Shows Investigational BIBF 1120 Demonstrated Positive Trend in Reducing Lung Function Loss in Idiopathic Pulmonary Fibrosis
9. Obese Patients Treated With QNEXA Demonstrated Significant Improvement in Quality of Life
10. Preclinical Studies in Pancreatic Cancer and Melanoma Demonstrated ADI-PEG 20 Works Synergistically With Inhibitors of Autophagy
11. Isis Pharmaceuticals Reports That Its Selective CRP Inhibitor Demonstrated Activity in a Phase 1 Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... SAN DIEGO , Oct. 1, 2014  ResMed (NYSE: ... people sleep and the first company to design complete sleep ... to educate women about the importance of a good night,s ... initiative will challenge the myth that feeling tired is just ... to understand that sleep is a critical pillar of health, ...
(Date:10/1/2014)... and NEW YORK , October 1, ... Research Organization (CRO) and service provider for the medical industries, announced ... of offices in New York City . genae ... City is strategically centered in one of the highest ... Coast", said Philippe Kassab , President at genae Americas. "The ...
(Date:10/1/2014)... 1, 2014 NeuroCall, Inc., ("NeuroCall") announced today ... Telestroke and Teleneurology services. Dr. Ricardo Garcia-Rivera , ... are extremely proud that our quality of service has ... to provide lifesaving support and continuity of care to ... the United States ." ...
Breaking Medicine Technology:ResMed Launches Initiative to Help Women Get Better Sleep 2ResMed Launches Initiative to Help Women Get Better Sleep 3genae Opens Offices in New York City 2NeuroCall Awarded Joint Commission Accreditation 2
... Despite difficult economic conditions, Allied Healthcare Products (Nasdaq: ... in the first quarter of fiscal year 2011. Sales increased ... for the first quarter of fiscal 2010. An ... carbon dioxide absorbent products used in anesthesia procedures narrowly tipped ...
... Systems Ltd. (Nasdaq: DHRM ) ("Dehaier" or ... marketing and sale of medical devices and homecare medical ... a $2 million medical device distribution bid for a ... Bank Corp ("CDB"). CDB is a ...
Cached Medicine Technology:Allied Healthcare Products Reports Narrow Loss for Quarter But Improves Year-Over-Year Performance 2Allied Healthcare Products Reports Narrow Loss for Quarter But Improves Year-Over-Year Performance 3Allied Healthcare Products Reports Narrow Loss for Quarter But Improves Year-Over-Year Performance 4Dehaier Medical Wins $2 Million Distribution Bid for Rural Healthcare Construction Project 2Dehaier Medical Wins $2 Million Distribution Bid for Rural Healthcare Construction Project 3
(Date:10/1/2014)... Familylifeinsurancequotes.org has released a new blog ... citizens. , Senior citizens can qualify for affordable ... to seniors who are over 50 years old. Some ... a medical examination. , Term life insurance with a ... can qualify. Having life insurance during retirement is important ...
(Date:10/1/2014)... Marriagelifeinsurance.com has released a new blog post ... , Senior citizens can purchase a joint life ... ones. A joint policy is cheaper, but will only ... , Life insurance can be used to cover important ... purchased online, as the application process is simple and ...
(Date:10/1/2014)... Insuranceragents.info has released a new blog post explaining ... vulnerable family members. , Life insurance plans provide important ... family should always carry a life insurance policy as ... of the family. , Clients can choose from ... temporary coverage or from a permanent policy. No medical ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Bedros Keuilian ... Body Boot Camp fitness boot camps, he’s also considered ... training , with sold out business summits, a line ... marketing consultant to a recent Spike TV reality show ... that now is the time for personal trainers and ...
(Date:10/1/2014)... Lifeinsurance-policy.com has released a new blog ... prices for smokers. , Smoking will always have a ... is the best method to find affordable coverage. Insurance ... need coverage. , Whole life insurance premiums will ... Since the coverage is permanent, the initial rates ...
Breaking Medicine News(10 mins):Health News:Affordable Term Life Insurance - Senior Citizens Can Qualify for Coverage! 2Health News:Elderly Life Insurance - Find Life Insurance for Retired Couples! 2Health News:Life Insurance for Families - Clients Can Compare Affordable Rates Online! 2Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 2Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 3Health News:Affordable Whole Life Insurance Premiums for Smokers! 2
... 19 GlaxoSmithKline (NYSE: GSK ),today reported ... million, equivalent to almost 4% of pre-tax profits ... 1%). Donations of albendazole treatments,for the company,s flagship ... were valued at $29 million, bringing the,total number ...
... in heparin samples , , WEDNESDAY, March 19 (HealthDay News) ... found in the blood-thinner heparin, which has been linked ... in the United States. , The contaminant is a ... and Drug Administration officials could not say Wednesday how ...
... before ... Patients, ST. LOUIS ... side, International Union of Operating,Engineers Local 49 leaders today at a news ... medical coverage to,several thousand Minnesota seniors., "This is a death sentence ...
... drug-resistant bacteria, CDC study finds , , WEDNESDAY, March 19 ... aureas bacterium and caught outside of the hospital ... than previously believed, preliminary research suggests. , "Over the ... a severe CAP [community-acquired pneumonia] caused by S. ...
... at the University of Pennsylvania School of Medicine have ... the molecular pathways underlying sleep apnea, which affects more ... of Health. Sleep apnea is a condition characterized by ... occur dozens or even hundreds of times a night. ...
... (PRI),and Medicos, Inc. are pleased to announce that over ... mobile version of,the MPR drug databases. For over 23 ... print editions of MPR for up-to-date, concise drug,information at ... drug,information on computers and mobile devices in all 50 ...
Cached Medicine News:Health News:GSK Charitable Support Valued at $564 Million in 2007 2Health News:GSK Charitable Support Valued at $564 Million in 2007 3Health News:FDA Identifies Contaminant in Blood-Thinning Drug 2Health News:FDA Identifies Contaminant in Blood-Thinning Drug 3Health News:Park Nicollet to Cut Off Care to Thousands of Minnesota Seniors 2Health News:Community-Based Staph Pneumonia More Common Than Thought 2Health News:Molecular biology of sleep apnea could lead to new treatments 2Health News:eMPR Digital Drug Reference Reaches 50,000 Downloads and the Publisher Launches a Raffle for Healthcare Providers 2Health News:eMPR Digital Drug Reference Reaches 50,000 Downloads and the Publisher Launches a Raffle for Healthcare Providers 3
... IntraLase FS laser introduces new high precision ... now have the opportunity to offer their ... a microkeratome for creating the corneal flap. ... laser and proprietary IntraLASIK software, surgeons may ...
... Teco Diagnostics manufactures fine urine chemistry ... urine chemistry reagent strips from start ... offer more economical prices compared to ... quality. Teco Diagnostics urine reagent strips ...
... with diabetes continue to have a tremendous ... life of patients, in addition to the ... to be associated with elevated levels of ... of haemoglobin A1c (HbA1c) in a diabetic ...
The Lifestream Plus Cholesterol Monitor provides you with a comprehensive tool to help you monitor your cholesterol as part of your wellness program....
Medicine Products: