Navigation Links
DEXILANT (dexlansoprazole) Product Information Updated Regarding Coadministration with Plavix (clopidogrel bisulfate)
Date:11/17/2011

cs of clopidogrel in healthy subjects. The study showed that the area under the curve (AUC) of the active metabolite of clopidogrel was reduced by approximately 9 percent (mean AUC ratio was 91 percent, with 90 percent CI of 86-97 percent) when DEXILANT was coadministered compared to administration of clopidogrel alone.

Pharmacodynamic parameters were also measured and demonstrated that the change in inhibition of platelet aggregation (induced by 5 mcM ADP) was related to the change in the exposure to clopidogrel active metabolite. The clinical significance of this finding is not clear. These results were presented at the American College of Cardiology (ACC) 2011 60th Annual Scientific Session in April 2011.

Takeda worked with the FDA to determine the appropriate information to be included in the revised DEXILANT product labeling. This information can be found in the labeling's Drug Interactions and Clinical Pharmacology sections. The Drug Interactions section specifically states that no dose adjustment of Plavix is necessary when administered with an approved dose of DEXILANT.

"We are pleased to add this information into the DEXILANT labeling enabling us to provide a clearer understanding for health care prescribers about the co-administration of DEXILANT and Plavix," said Gilles Delecoeuillerie, M.D., Ph.D., executive medical director, Medical & Scientific Affairs, Gastroenterology and Internal Medicine, Takeda. "Takeda conducted this study to further understand how DEXILANT may interact with clopidogrel and to ensure that patients with GERD, who are treated with both medications, have the most up to date coadministration information."

About DEXILANT (dexlansoprazole) 30 mg and 60 mg delayed release capsules

DEXILANT is a PPI, which decreases acid production by turning off many of the acid pumps in the stomach, thus helping to protect the esophagus from acidic reflux so that esophageal inflammation can heal. DEXIL
'/>"/>

SOURCE Takeda Pharmaceuticals North America, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Handa Pharmaceuticals Announces Submission of Its First-to-File ANDA for Takedas DEXILANT®
2. Data Presented at DDW About Rebound Symptoms in Healed Erosive Esophagitis Patients After Completion of Treatment with DEXILANT(TM) (dexlansoprazole)
3. Proton Pump Inhibitor DEXILANT(TM) (dexlansoprazole) Now Available in U.S. Pharmacies
4. KAPIDEX(TM) (dexlansoprazole) Renamed DEXILANT(TM) in U.S. to Avoid Name Confusion
5. New Study Results Analyzed the Use of KAPIDEX(TM) (dexlansoprazole) for Nighttime Heartburn in Adults with Non-Erosive GERD
6. White Smile Global Inc. Corporate Update on the White Smile Premier™ "At-Home" LED Teeth Whitening System and the White Smile Tooth Gloss™, Including Clinical Study, Product Manufacturing, and Distribution
7. 72 Prominent Personalized Medicine Products Available; A Five-Fold Increase in Five Years
8. Novation Awards ICU Medical, Inc. a New Contract to Supply Members With a Complete Line of Clinically-Preferred Critical Care Products
9. Landauer, Inc. Announces Acquisition of IZI Medical Products, LLC
10. Regado Biosciences, Inc. Presents Three Abstracts Pertaining to its Pipeline of Reversible Antithrombotic Agents, Including the Substudy Analyses of its Phase 2b RADAR Trial for REG1, its Lead Product Candidate, at the American Heart Association (AH
11. Apelon Provides Products and Services to Support Canadian Healthcare Data Standardization
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... -- Ameritox,s Ingenuity Health, a leading provider of monitoring solutions ... the National Council of Behavioral Health annual conference in ... 25 percent of the samples collected from patients with ... antipsychotic medication. ... Medication nonadherence can ...
(Date:4/20/2015)... 2015 International Isotopes Inc. (OTCQB: INIS, ... with the following update on its business segments. ... Historically, INIS has produced and sold high-activity ... of sealed sources for medical and industrial applications.  ... security examination, and radiography.  Due to technical issues ...
(Date:4/20/2015)... NEW YORK , April 20, 2015 /PRNewswire/ ... insulin pump market will continue to be robust; ... increasing incidence of diabetes, expanding global markets, new ... growth, there are relatively steady market inhibitors, such ... and an increasing competitive environment. The healthcare market ...
Breaking Medicine Technology:Ingenuity Health Research Flags Potentially High Rate of Medication Nonadherence Among Those with Serious Mental Illness 2Ingenuity Health Research Flags Potentially High Rate of Medication Nonadherence Among Those with Serious Mental Illness 3International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 2International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 3International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 4International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 5Kalorama: Insulin Pump Market Growing Robustly 2Kalorama: Insulin Pump Market Growing Robustly 3
... HASCO Medical, Inc. (OTC Bulletin Board: HASC ... serves patients in Alabama, Florida, and Mississippi, today announced ... additional 8,000+ products available for immediate delivery. ... and affordable for patients throughout the United States to ...
... 25, 2011 Elekta,s MOSAIQ®* oncology electronic ... certification. Complete EMR certification officially validates the Elekta ... demonstrate Stage 1 meaningful use under the HITECH ... the Drummond Group,s Electronic Health Records Office of ...
Cached Medicine Technology:HASCO Medical Expands Online Offering 2Elekta's Oncology-Specific MOSAIQ Receives Complete ONC-ATCB EMR Certification 2Elekta's Oncology-Specific MOSAIQ Receives Complete ONC-ATCB EMR Certification 3
(Date:4/21/2015)... The University of Scranton has launched ... to answer the growing demand for professionals trained ... wellness profile for better individual, real-world care. , ... implementation of health services and systems. This is ... operations in the healthcare sector,” says Margarete Zalon, ...
(Date:4/21/2015)... (PRWEB) April 21, 2015 On ... the grand opening of its Center for Graduate ... Hollywood Presbyterian Hospital. The campus recently completed a ... the only thing that has administrators and students ... expanded from the Master of Science in Nursing, ...
(Date:4/21/2015)... Springs, FL (PRWEB) April 21, 2015 ... these are a few of the Earth Day topics ... As state and national leaders debate the affect of ... offers a variety of subject matter touching on the ... The compelling segments will delve into sustainable lifestyles, clean ...
(Date:4/21/2015)... This program provides physical therapists, ... occupational therapist assistants, teachers, and other school based ... children across the autism spectrum succeed in the ... Inc. , Used throughout the United ... yoga curriculum addresses learning and behavior issues across ...
(Date:4/20/2015)... Falls Church, VA (PRWEB) April 21, 2015 ... How Sponsors and CMOs Speed Production and Improve Compliance ... – 3:00 p.m. EDT, http://www.fdanews.com/qualitybydesign , The ... that are forcing them to do more with less. ... forcing sponsors and CMOs to finds ways to speed ...
Breaking Medicine News(10 mins):Health News:The University of Scranton Launches Online MS in Health Informatics 2Health News:The University of Scranton Launches Online MS in Health Informatics 3Health News:West Coast University Opens a Center for Graduate Studies 2Health News:West Coast University Opens a Center for Graduate Studies 3Health News:USM Studios’ Programming Focuses on the Environment 2Health News:ABC News Interviews Anne Buckley-Reen, Education Resources Inc. Faculty Member, on Yoga Therapy in the Classroom 2Health News:FDAnews Announces — Using Quality by Design to Improve Manufacturing: How Sponsors and CMOs Speed Production and Improve Compliance Webinar, May 7, 2015 2Health News:FDAnews Announces — Using Quality by Design to Improve Manufacturing: How Sponsors and CMOs Speed Production and Improve Compliance Webinar, May 7, 2015 3
... RBC Life Sciences (OTC Bulletin Board: RBCL) announced ... Price, to CEO effective January 1, 2009. Company founder, ... chairman of the board of directors.The promotion comes at ... of proprietary nutritional supplements, wound care and pain management ...
... Dental Network of America (DNoA) and Philips Consumer ... America Corporation (Philips), just signed an agreement, effective ... "DNoA Preferred Network" dentists in Illinois, Oklahoma and ... Sonicare(TM) product line."Partnering with Philips on offering the ...
... January 30th noon to 5PM in our new Hyundai Dealer showroom at 271 ... the first 50 to donate blood. , ... Wilmington, MA (PRWEB) January 5, 2009 -- Bill Dube ... blood as the recent ice & snow storms that hit New England have canceled ...
... China, Jan. 5 /PRNewswire-Asia-FirstCall/ -- China Nepstar Chain,Drugstore ... "the Company"), the largest retail,drugstore chain in China ... announced that its Board of Directors and the ... termination of a voting rights agreement which,assigned 30% ...
... foods consumed during pregnancy might protect against asthma and ... apple a day while you,re pregnant may indeed keep ... your unborn child. , Recent research suggests ... have lower rates of asthma. , And, mothers who ...
... Today,s fast-paced,demanding culture often makes it challenging to ... health. Karate, which is most commonly,recognized as a means ... to help anyone achieve a fit body; relieve stress; ... her leadership skills. , Karate ...
Cached Medicine News:Health News:RBC Life Sciences Promotes Industry Veteran John W. Price to CEO; Company Founder, Clinton Howard, Will Remain Chairman of the Board 2Health News:RBC Life Sciences Promotes Industry Veteran John W. Price to CEO; Company Founder, Clinton Howard, Will Remain Chairman of the Board 3Health News:Dental Network of America and Philips Sign Agreement to Offer Sonicare Products to Dental Providers 2Health News:Boston Hyundai Dealer Teams up With the Red Cross to Save Lives 2Health News:China Nepstar Chain Drugstore Terminates Voting Rights Agreement for Yunnan Subsidiary 2Health News:China Nepstar Chain Drugstore Terminates Voting Rights Agreement for Yunnan Subsidiary 3Health News:China Nepstar Chain Drugstore Terminates Voting Rights Agreement for Yunnan Subsidiary 4Health News:Prenatal Nutrition, Postnatal Allergy Protection 2Health News:Prenatal Nutrition, Postnatal Allergy Protection 3Health News:Karate For Your Body Announces Release of Volume One in Martial Arts DVD Training Series, 'Focusing On Fundamentals' 2
... The Bledsoe Wee Walker Pediatric ... low profile pediatric boot that ... unsurpassed support. Only two sizes ... cost. These sizes will fit ...
... is a shorter and lighter version ... second degree ankle sprains, toe and ... Bledsoe EZ Set Mid-Calf Boot is ... 20 degrees of dorsi-flexion to 40 ...
... Diabetic Boot features a fully enclosed thick, ... unique auto-molding innersole which embeds into a ... aluminum shelled walking boot. This unique Automold™ ... distribute body weight across the entire bottom ...
... Bird and Cronin, ... manufacturer of Patient Footwear, ... Patient Care Products. Our ... highest quality and available ...
Medicine Products: