Navigation Links
DEXILANT (dexlansoprazole) Product Information Updated Regarding Coadministration with Plavix (clopidogrel bisulfate)
Date:11/17/2011

cs of clopidogrel in healthy subjects. The study showed that the area under the curve (AUC) of the active metabolite of clopidogrel was reduced by approximately 9 percent (mean AUC ratio was 91 percent, with 90 percent CI of 86-97 percent) when DEXILANT was coadministered compared to administration of clopidogrel alone.

Pharmacodynamic parameters were also measured and demonstrated that the change in inhibition of platelet aggregation (induced by 5 mcM ADP) was related to the change in the exposure to clopidogrel active metabolite. The clinical significance of this finding is not clear. These results were presented at the American College of Cardiology (ACC) 2011 60th Annual Scientific Session in April 2011.

Takeda worked with the FDA to determine the appropriate information to be included in the revised DEXILANT product labeling. This information can be found in the labeling's Drug Interactions and Clinical Pharmacology sections. The Drug Interactions section specifically states that no dose adjustment of Plavix is necessary when administered with an approved dose of DEXILANT.

"We are pleased to add this information into the DEXILANT labeling enabling us to provide a clearer understanding for health care prescribers about the co-administration of DEXILANT and Plavix," said Gilles Delecoeuillerie, M.D., Ph.D., executive medical director, Medical & Scientific Affairs, Gastroenterology and Internal Medicine, Takeda. "Takeda conducted this study to further understand how DEXILANT may interact with clopidogrel and to ensure that patients with GERD, who are treated with both medications, have the most up to date coadministration information."

About DEXILANT (dexlansoprazole) 30 mg and 60 mg delayed release capsules

DEXILANT is a PPI, which decreases acid production by turning off many of the acid pumps in the stomach, thus helping to protect the esophagus from acidic reflux so that esophageal inflammation can heal. DEXIL
'/>"/>

SOURCE Takeda Pharmaceuticals North America, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Handa Pharmaceuticals Announces Submission of Its First-to-File ANDA for Takedas DEXILANT®
2. Data Presented at DDW About Rebound Symptoms in Healed Erosive Esophagitis Patients After Completion of Treatment with DEXILANT(TM) (dexlansoprazole)
3. Proton Pump Inhibitor DEXILANT(TM) (dexlansoprazole) Now Available in U.S. Pharmacies
4. KAPIDEX(TM) (dexlansoprazole) Renamed DEXILANT(TM) in U.S. to Avoid Name Confusion
5. New Study Results Analyzed the Use of KAPIDEX(TM) (dexlansoprazole) for Nighttime Heartburn in Adults with Non-Erosive GERD
6. White Smile Global Inc. Corporate Update on the White Smile Premier™ "At-Home" LED Teeth Whitening System and the White Smile Tooth Gloss™, Including Clinical Study, Product Manufacturing, and Distribution
7. 72 Prominent Personalized Medicine Products Available; A Five-Fold Increase in Five Years
8. Novation Awards ICU Medical, Inc. a New Contract to Supply Members With a Complete Line of Clinically-Preferred Critical Care Products
9. Landauer, Inc. Announces Acquisition of IZI Medical Products, LLC
10. Regado Biosciences, Inc. Presents Three Abstracts Pertaining to its Pipeline of Reversible Antithrombotic Agents, Including the Substudy Analyses of its Phase 2b RADAR Trial for REG1, its Lead Product Candidate, at the American Heart Association (AH
11. Apelon Provides Products and Services to Support Canadian Healthcare Data Standardization
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... , Aug. 4, 2015 Organovo ... biology company focused on delivering scientific and medical ... the Company has hired Paul Gallant ... tissue service and product business. Mr. Gallant has more ... in the drug discovery industry, most recently serving ...
(Date:8/4/2015)... -- Research and Markets ( ... PharmaBiotech,s new report "Animal Biotechnology - Technologies, ... This report describes and evaluates animal biotechnology ... as well as improvement in food production. Knowledge ... of biotechnology to manage genetic disorders and improve ...
(Date:8/4/2015)... EDISON, N.J. , Aug. 4, 2015 /PRNewswire/ ... biopharmaceutical company focused on the development and commercialization ... Sapirstein , Chief Executive Officer, will present live ... DATE: Thursday, August 6, 2015 TIME: 12:15PM EDT ... will be a live, interactive online event where ...
Breaking Medicine Technology:Organovo Holdings, Inc. Appoints Paul Gallant as General Manager 2Organovo Holdings, Inc. Appoints Paul Gallant as General Manager 3Animal Biotechnology 2014-2024 - 2015 Technologies, Markets and Companies Analysis 2Animal Biotechnology 2014-2024 - 2015 Technologies, Markets and Companies Analysis 3ContraVir to Webcast Investor Presentation on August 6: VirtualInvestorConferences.com 2ContraVir to Webcast Investor Presentation on August 6: VirtualInvestorConferences.com 3
... N.J., Oct. 12, 2011 Savient Pharmaceuticals, Inc. (NASDAQ: ... financial results for the third quarter 2011 prior to the ... John H. Johnson, Chief Executive Officer and President, ... Officer, will host an investment community conference call beginning at ...
... 12, 2011 If you could learn that you have a ... and 75 percent of that chance could be altered by lifestyle ... of the nation,s leading online direct-to-consumer online lab test and health ... Your Number HealthScore as seen on The Biggest Loser ...
Cached Medicine Technology:Savient Pharmaceuticals to Hold Third Quarter 2011 Financial Results Conference Call on Thursday, November 3, 2011 2PersonaLabs and BioSignia Join to Offer Targeted Risk Assessment 2
(Date:8/4/2015)... (PRWEB) , ... August 04, 2015 , ... Angelina Jolie ... that affects millions of women every year. Dr. Angela DeRosa, DO, MBA, CPE ... hormone replacement therapies, takes the scary unknown out of menopause. , Myth #1: ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... States, Richard Carmona, M.D., M.P.H., FACS, to its Board of Directors effective August ... save lives," Dr. Carmona said. "I strongly believe in the mission of the ...
(Date:8/4/2015)... Dublin, Ohio (PRWEB) , ... August 04, 2015 , ... ... days of summer in the sun and preparing for the back-to-school scramble. Dublin, ... of summer is the best time for the annual dental checkup. In fact, the ...
(Date:8/4/2015)... (PRWEB) , ... August 04, 2015 , ... ... Kingdom and other international locations have shown a rise in binge drinking among ... link between binge drinking and depression, are continuing to examine trends and evidence ...
(Date:8/4/2015)... Horeb, WI (PRWEB) , ... August 04, 2015 , ... ... released video on the subject, Renew Man™ is standing up as a voice of ... 15-year veteran of the healthy aging industry with special experience and expertise in the ...
Breaking Medicine News(10 mins):Health News:"Dr. Hot Flash" Debunks the Top 5 Menopause Myths 2Health News:"Dr. Hot Flash" Debunks the Top 5 Menopause Myths 3Health News:Dr. Richard Carmona, 17th Surgeon General of the United States, Joins PerceptiMed, Inc.’s Board of Directors 2Health News:Dr. Richard Carmona, 17th Surgeon General of the United States, Joins PerceptiMed, Inc.’s Board of Directors 3Health News:Dublin OH Family Dentist Offers Complimentary Back-to-School Cleanings, a Revamped Suite, and In-House Esthetician to Accommodate All Patients 2Health News:Dublin OH Family Dentist Offers Complimentary Back-to-School Cleanings, a Revamped Suite, and In-House Esthetician to Accommodate All Patients 3Health News:Dublin OH Family Dentist Offers Complimentary Back-to-School Cleanings, a Revamped Suite, and In-House Esthetician to Accommodate All Patients 4Health News:DARA Responds To International Trends in Binge Drinking 2Health News:DARA Responds To International Trends in Binge Drinking 3Health News:New Video from Renew Man™ Raises Awareness of the Right Way to Correct Low Testosterone 2Health News:New Video from Renew Man™ Raises Awareness of the Right Way to Correct Low Testosterone 3
... Benefits,(NYSE: ING ) has announced the launch ... complement to traditional health and disability,insurance, Premier Critical ... for enrolled participants in the event they,experience a ... to,employers to add to their benefit portfolios with ...
... Dec. 3 Masimo (Nasdaq: MASI ),the ... Low Perfusion,pulse oximetry, reported that multiple independent and ... at the 2007 American,Association of Respiratory Care (AARC) ... capabilities of Masimo,s noninvasive patient,monitoring technologies in the ...
... to blame, researchers say , MONDAY, Dec. 3 (HealthDay News) ... other males to develop the eating disorder anorexia nervosa, scientists ... female sex hormones in the womb may be associated with ... , "Anorexia nervosa is approximately 10 times more common in ...
... Seniors who take a close look at,the Part ... reap,handsome savings next year. Many Medicare HMO and PPO ... deductibles with either complete or,partial coverage throughout the "gap" ... bills until reaching $4,050 in out-of-pocket costs).,HealthMetrix Research Inc. ...
... Imaging Management Services for SWHP, DEERFIELD, Ill., ... subsidiary of WellPoint, Inc. (NYSE: WLP ), ... with health,plan clients representing over 20 million consumers, ... a radiology quality program around,diagnostic imaging services for ...
... tool for treating a variety of brain disorders--including tumors--is ... The new machine expands UCSFs ability to provide ... Leksell Gamma Knife Perfexion, the machine is the latest ... delivers a finely focused, high dose of radiation to ...
Cached Medicine News:Health News:ING Employee Benefits Announces New Critical Illness Insurance Product 2Health News:ING Employee Benefits Announces New Critical Illness Insurance Product 3Health News:Breaking Studies at AARC Congress Show Masimo SET and Masimo Rainbow SET to be Accurate, Effective and Uniquely Beneficial in Detecting and Tracking Disease States 2Health News:Breaking Studies at AARC Congress Show Masimo SET and Masimo Rainbow SET to be Accurate, Effective and Uniquely Beneficial in Detecting and Tracking Disease States 3Health News:Breaking Studies at AARC Congress Show Masimo SET and Masimo Rainbow SET to be Accurate, Effective and Uniquely Beneficial in Detecting and Tracking Disease States 4Health News:Breaking Studies at AARC Congress Show Masimo SET and Masimo Rainbow SET to be Accurate, Effective and Uniquely Beneficial in Detecting and Tracking Disease States 5Health News:Breaking Studies at AARC Congress Show Masimo SET and Masimo Rainbow SET to be Accurate, Effective and Uniquely Beneficial in Detecting and Tracking Disease States 6Health News:Having Twin Sister Boosts Men's Anorexia Risk 2Health News:HealthMetrix Research Finds Medicare Advantage Plans Offer Seniors Opportunity to Lower Their 2008 Out-of-Pocket Drug Costs 2Health News:HealthMetrix Research Finds Medicare Advantage Plans Offer Seniors Opportunity to Lower Their 2008 Out-of-Pocket Drug Costs 3Health News:American Imaging Management Enters into Agreement with Scott & White Health Plan 2Health News:UCSF Medical Center using newest high-tech tool for brain disorders 2
... most potent, naturally secreted estrogen and is ... [1]. In the ovary, estradiol is produced ... less potent estrogen derived from androstenedione. Estrone ... tissues. In men, small amounts of estradiol ...
... has been useful in the differential diagnosis ... with chest pain. 18-20 ... of sensitive and specific biomarkers, such as ... kinase (CK-MB), and myoglobin, are increased in ...
The second-generation Dade Behring Acute Care Troponin I (cTnI) method is the first FDA cleared high sensitivity cTnI assay with the low-end precision necessary to meet the ESC/ACC guidelines (CV <10...
... The VITROS ECi brings true ... to immunodiagnostic testing. Highly sensitive assays ... oncology and bone metabolism testing are ... under development. The VITROS ECi can ...
Medicine Products: