Navigation Links
Cytopia Scientific Presentations on JAK2 Inhibitor Program
Date:10/15/2008

MELBOURNE, Australia, Oct. 16 /PRNewswire/ -- Cytopia Limited (ASX: CYT) will present data on its JAK2 inhibitor program at two important scientific meetings this month.

Dr Emmanuelle Fantino, Head of Biology at Cytopia, will present a lecture entitled Targeted JAK2 Inhibitors for Myeloproliferative Disorders at the annual meeting of the Hematological Society of Australia and New Zealand, in Perth, Australia, on 21 October, 11:15am AWST.

Dr Christopher Burns, Cytopia's Research Director, will present his lecture JAK2 Inhibitors for Myeloproliferative Disorders at the 'Drug Discovery on Target' conference in Boston USA, on 22 October, 10:40am US EDT.

Both presentations will describe the very promising data generated for the company's lead JAK2 drug candidate CYT387 in a variety of in vitro and in vivo studies, supporting its development as a potent and selective compound for treating myeloproliferative disorders (MPDs).

Subject to regulatory approval, the company intends to commence a Phase I/II clinical study in patients with MPDs in early 2009. The study will be chaired by Dr Ayalew Tefferi of the Mayo Clinic, Rochester USA.

About JAK2

The discovery of a specific single activating mutation in the JAK2 enzyme in MPDs in 2005 has focused attention on developing a therapy for these diseases through selective inhibition of JAK2. To successfully address these chronic diseases with a JAK2 inhibitor, the specificity and resultant tolerability profile is a key element of the product profile required for a "best in class" inhibitor. Cytopia is a world leader in JAK2 kinase chemistry and holds a broad range of JAK2 related patents. The main focus of the JAK2 program is developing orally available JAK2 inhibitors to treat MPDs including myelofibrosis, polycythemia vera (PV) and essential thrombocythemia (ET). CYT387 is a specific JAK2 inhibitor with excellent potential for safe and efficacious chronic human dosing. It has been
'/>"/>

SOURCE Cytopia Limited
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Cytopia Nominates JAK2 Clinical Candidate for Myeloproliferative Disorders
2. Cytopia Announces Novel Anti-Cancer Drug Development Collaboration
3. Release of Cytopia Abstract for CYT997 Oral Presentation at American Society of Clinical Oncology
4. Cytopia Appoints Study Chairman for JAK2 Clinical Trial
5. Cytopia Commences Second Phase II Study in Brain Cancer
6. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
7. Avicena Scientific Collaborator Advances Program for Using Energy Enhancing Molecules to Treat Neuromuscular Diseases
8. Boston Scientific Announces Schedule for European Society of Cardiology Congress 2007
9. Boston Scientific to Release Broad Range of Clinical Trial Data Reinforcing Safety and Efficacy of Taxus(R) Coronary Stent Systems at TCT 2007
10. Preliminary Results of Randomized Pilot Study Show Comparable Efficacy for OrbusNeichs Genous(TM) Bio-engineered R Stent(TM) and Boston Scientifics Taxus(R) Stent in Patients at High Risk of Restenosis
11. Boston Scientific PROMUS(TM) and TAXUS(R) Stents Continue Strong Performance in Safety and Efficacy Measures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... March 27, 2015 A new report from Kalorama ... – Chile , ... top targets for IVD firms.  The healthcare research firm said ... IVD strategies for the Latin American continent with a population ... distributed supply operations. However, the country,s regional economic clout does ...
(Date:3/27/2015)... March 27, 2015 Zimmer Holdings, Inc. (NYSE and ... system for trauma patients. Available in both ... ® External Fixation System from Zimmer is a modular ...   The XtraFix System allows surgeons to ... external fixation process, resulting in saved time, costs and overall ...
(Date:3/27/2015)... 2015 CHINA AID, ... Care, Rehabilitation Medicine and Healthcare, second to none in ... be held at Shanghai New International Expo Center on ... Implementation Suggestions on Encouraging Private Capital to Participate in ... jointly issued by the Ministry of Civil Affairs of ...
Breaking Medicine Technology:Kalorama: Beyond Brazil, Latin American IVD Market Grows 2Kalorama: Beyond Brazil, Latin American IVD Market Grows 3Kalorama: Beyond Brazil, Latin American IVD Market Grows 4Zimmer Debuts New Modular External Fixation System 2Zimmer Debuts New Modular External Fixation System 3CHINA AID, the 10th China International Exhibition of Senior Care, Rehabilitation Medicine and Healthcare to be held in April 2CHINA AID, the 10th China International Exhibition of Senior Care, Rehabilitation Medicine and Healthcare to be held in April 3CHINA AID, the 10th China International Exhibition of Senior Care, Rehabilitation Medicine and Healthcare to be held in April 4CHINA AID, the 10th China International Exhibition of Senior Care, Rehabilitation Medicine and Healthcare to be held in April 5CHINA AID, the 10th China International Exhibition of Senior Care, Rehabilitation Medicine and Healthcare to be held in April 6
(Date:3/28/2015)... March 28, 2015 One in three ... to research presented today at the American Orthopaedic Society ... study examined the long term success of surgery for ... examined survey data from 242 patients who underwent ACL ... P. Roe, MBBS, FRACS, from North Sydney Orthopaedic and ...
(Date:3/28/2015)... 2015 Andrew Hawley of Vintage Rock Posters ... concert posters. The Who and the Doors played together at ... 1968. According to Hawley, “The Who toured the United States ... college campuses. Perhaps the most famous Who poster was a ... the Doors on August 2, 1968 at the Singer Bowl ...
(Date:3/28/2015)... Designers and Professionals of FCPX plugins ... from Pixel Film Studios. , “Scratches 5K allows users ... Final Cut Pro X” Said Christina Austin, CEO of ... an effective tool for any FCPX editor.” , Scratch ... grunge overlays. Simply drag title layers into the FCPX ...
(Date:3/27/2015)... The Monogamy Method - a new ... Jason Rogers has just been released to the public ... surrounding the course's launch has caught the attention of ... review of the new program. , "Many women report ... suddenly start pulling away or expressing interest in other ...
(Date:3/27/2015)... March 27, 2015 First Choice Emergency ... The new facility is located 12665 W Lake Houston Pkwy, ... resident of Summerwood, I look forward to delivering the highest ... Sowell, Facility Medical Director of First Choice Emergency Room Summerwood. ... Room made a donation to Summer Creek High School at ...
Breaking Medicine News(10 mins):Health News:Young Athletes at Greater Risk for Re-Injury after ACL Surgery 2Health News:Avid Collector from Vintage Rock Posters, Inc. Announces His Search For Original 1960's Who Psychedelic Concert Posters. 2Health News:Pixel Film Studios Unveiled Scratches 5k for Final Cut Pro X Editors 2Health News:The Monogamy Method - Review Of Samantha Sanderson & Jason Rogers' Relationship Program Released 2Health News:First Choice Emergency Room Opens New Facility in Houston, Texas 2
... singing reduced the blood pressure of a 76-year-old ... to total knee replacement surgery for osteoarthritis (OA). ... interventions, the woman,s blood pressure dropped dramatically when ... in the April issue of Arthritis Care ...
... News) -- Obese patients are twice as likely as ... a general anesthetic, a new study has found. ... to develop such problems, according to the report. ... that occurred among patients who received general anesthesia in ...
... , NEW YORK (March 29, 2011) -- Bariatric surgery is ... moderately and severely obese patients. These findings and others were ... for Type 2 Diabetes, hosted by NewYork-Presbyterian Hospital and Weill ... effectiveness is central to the larger issue of access to ...
... -- Problem gambling is more common among American adults than ... the Research Institute on Addictions at the University of Buffalo, ... gambling is rare. The researchers analyzed two national surveys ... of 2,274 younger people, aged 14 to 21 -- to ...
... bodies is only indirectly connected to their body mass index ... according to recent research. The most powerful influence ... important others view them, the study suggests. On the flip ... inner workings of their body or how their bodies ...
... at castle walls is one way to attack an ... vulnerable. Researchers at Cedars-Sinai,s Maxine Dunitz Neurosurgical Institute ... to target important mechanisms inside the most challenging breast ... approach effective in attacking malignant brain tumor targets. ...
Cached Medicine News:Health News:Case study reports singing lowers patient's blood pressure prior to surgery 2Health News:Obesity Could Raise Risks of General Anesthesia 2Health News:Bariatric surgery highly cost-effective treatment for type 2 diabetes in the obese 2Health News:Bariatric surgery highly cost-effective treatment for type 2 diabetes in the obese 3Health News:Bariatric surgery highly cost-effective treatment for type 2 diabetes in the obese 4Health News:Younger, Poorer People More Prone to Problem Gambling 2Health News:Women's body image based more on others' opinions than their own weight 2Health News:Women's body image based more on others' opinions than their own weight 3Health News:Women's body image based more on others' opinions than their own weight 4Health News:New 'nanodrug' breaks down barriers to attack breast cancer cells from the inside out 2Health News:New 'nanodrug' breaks down barriers to attack breast cancer cells from the inside out 3
Curved with catch....
Clinical micro clamps by Acland. Black finish. It provides impressive security in use, both against slippage and against leakage due to controlled closing force and working grip surface....
Clinical micro clamps by Acland. Black finish. It provides impressive security in use, both against slippage and against leakage due to controlled closing force and working grip surface....
Clinical micro clamps by Acland. Matte finish. It provides impressive security in use, both against slippage and against leakage due to controlled closing force and working grip surface....
Medicine Products: