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Cynosure Announces Presentation of Favorable Results from Post-Marketing Studies of Smartlipo MPX
Date:4/2/2009

At three months, the average improvement in skin tightening was 62% with Smartlipo MPX compared with a 5% improvement on the side treated with liposuction.

"This is the first head-to-head quantitative study comparing the efficacy of the Smartlipo MPX workstation with that of liposuction, and the first study to illustrate the effects of subdermal applications of laser energy on skin laxity and tissue tightening," Dr. DiBernardo said. "The ability of Smartlipo MPX to lipolyze and remove unwanted areas of fat already has been clearly established. The results of our study now demonstrate that laser lipolysis can achieve greater skin tightening and skin shrinkage than liposuction alone."

Smartlipo MPX also was the focus of a post-marketing study conducted by Bruce Katz, M.D., Clinical Professor of Dermatology at The Mount Sinai School of Medicine and Director of the Juva Skin & Laser Center in New York. A total of 20 subjects with unwanted localized areas of fat and skin laxity were treated with Smartlipo MPX. In a subset of five patients, skin tightening through surface area reduction was measured with the use of temporary tattoo markings, and biopsies were performed before the procedure, as well as three days and one month post-treatment, to determine the presence of new collagen markers.

In addition to a reduction in localized fat deposits, the study demonstrated new collagen formation and an 18% decrease in skin surface area. "The data clearly indicate that Smartlipo MPX not only has a significant skin tightening effect, but also contributes to new collagen formation that is vital to skin tonicity," Dr. Katz said.

Cynosure President and Chief Executive Officer Michael Davin said, "These studies provide powerful scientific evidence that affirms the dramatic results already being observed by physicians and patients. We believe this research, and subsequent studies, will drive further a
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SOURCE Cynosure, Inc.
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