Navigation Links
CuraGen to Present CR011-vcMMAE Data at ASCO
Date:5/28/2009

ragen.com following the presentations.

Conference Call Details and Dial-in Information

    Date:       Wednesday, June 3, 2009
    Time:       11:00 a.m. EDT
    Dial-in:    (877)-856-1956  (U.S. and Canada)
                (719)-325-4771  (international)

Webcast: Access available at http://www.curagen.com

About CR011-vcMMAE

CR011-vcMMAE is an antibody-drug conjugate (ADC) being developed by CuraGen that consists of a fully-human monoclonal antibody, CR011, linked to a potent cell-killing drug, monomethyl-auristatin E (MMAE). The ADC technology, comprised of MMAE and a stable linker system for attaching it to CR011, was licensed from Seattle Genetics, Inc. The ADC is designed to be stable in the bloodstream. Following intravenous administration, CR011-vcMMAE targets and binds to GPNMB, a specific protein that is predominantly expressed on the surface of cancer cells, including melanoma, breast cancer and gliomas. Upon internalization into the targeted cell, CR011-vcMMAE is designed to release MMAE from CR011 to produce a cell-killing effect. CR011-vcMMAE is currently in two Phase II trials assessing the safety and efficacy in the treatment of melanoma and for the treatment of metastatic breast cancer, and in a Phase I trial to evaluate the safety and activity of alternate dosing schedules.

About Breast Cancer

Breast cancer is the most common cancer in women and a leading cause of death in the United States. According to the American Cancer Society, more than 180,000 women will be diagnosed with invasive breast cancer in 2009 with more than 40,000 deaths attributed to this disease. Despite recent advances in therapy, the median survival of patients with metastatic breast cancer is 2 to 3 years, while patients with "triple-nega
'/>"/>

SOURCE CuraGen Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. CuraGen Provides Update on Velafermin, Belinostat and CR011-vcMMAE Clinical Development Programs
2. CuraGen and TopoTarget Initiate Phase I/II Clinical Trial of Belinostat (PXD101) Combination Therapy for Acute Myeloid Leukemia
3. CuraGen Announces Top-Line Phase II Results on Velafermin
4. CuraGen Announces Presentation of Phase I Dose-Escalation Results on CR011- vcMMAE for Metastatic Melanoma
5. CuraGen and TopoTarget Announce Presentation of Belinostat Clinical Trial Results at AACR-NCI-EORTC International Conference
6. CuraGen and TopoTarget Announce Presentations on Belinostat at the Upcoming American Society of Hematology 49th Annual Meeting
7. CuraGen Advances CR011-vcMMAE into Phase II
8. CuraGen Announces Data From Ongoing Phase I/II Trial Showing Clinical Activity of CR011-vcMMAE in Metastatic Melanoma
9. CuraGen Announces Expansion of CR011-vcMMAE Phase II Trial in Melanoma
10. CuraGen Announces Initiation of Phase II Trial of CR011-vcMMAE in Patients with Advanced Breast Cancer
11. CuraGen Reports Second Quarter 2008 Financial Results and Clinical Progress of CR011-vcMMAE
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... LOS ANGELES , Aug. 4, ... ), the world,s leading provider of diagnostic information ... previously announced acquisition of MemorialCare Health System,s laboratory ... result of the transaction, patients and physicians now ... services and network of nearly 200 patient service ...
(Date:8/4/2015)... 2015  The Pittsburgh Life Sciences Greenhouse (PLSG), the ... that one of its portfolio companies, Medrobotics Corporation, has ... Robotic System in the U.S.  ... Medrobotics," said John W. Manzetti , president and ... way since spinning out of The Robotics Institute at ...
(Date:8/4/2015)... Calif., Aug. 4, 2015  Isis Pharmaceuticals, Inc. (Nasdaq: ... million and $18.9 million for the three and six ... net loss of $12.1 million and $43.4 million for ... results were driven primarily by the more than $90 ... related to the upfront payment from Bayer to license  ...
Breaking Medicine Technology:Quest Diagnostics Completes Acquisition of MemorialCare Health System's Laboratory Outreach Service Business in Southern California 2Pittsburgh Life Sciences Greenhouse Portfolio Client Medrobotics Receives FDA Market Clearance 2Pittsburgh Life Sciences Greenhouse Portfolio Client Medrobotics Receives FDA Market Clearance 3Isis Reports Financial Results And Highlights For Second Quarter 2015 2Isis Reports Financial Results And Highlights For Second Quarter 2015 3Isis Reports Financial Results And Highlights For Second Quarter 2015 4Isis Reports Financial Results And Highlights For Second Quarter 2015 5Isis Reports Financial Results And Highlights For Second Quarter 2015 6Isis Reports Financial Results And Highlights For Second Quarter 2015 7Isis Reports Financial Results And Highlights For Second Quarter 2015 8Isis Reports Financial Results And Highlights For Second Quarter 2015 9Isis Reports Financial Results And Highlights For Second Quarter 2015 10Isis Reports Financial Results And Highlights For Second Quarter 2015 11Isis Reports Financial Results And Highlights For Second Quarter 2015 12Isis Reports Financial Results And Highlights For Second Quarter 2015 13Isis Reports Financial Results And Highlights For Second Quarter 2015 14Isis Reports Financial Results And Highlights For Second Quarter 2015 15Isis Reports Financial Results And Highlights For Second Quarter 2015 16
... 2012  Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ), the ... a company overview at Citi,s 2012 Global Health Care Conference ... the Waldorf Astoria in New York City. A ... the "Investors & Media" section of the Company,s Web site, ...
... Feb. 21, 2012   Enanta Pharmaceuticals, Inc. , ... best-in-class small molecule drugs in the infectious disease ... an exclusive collaboration and license agreement with Novartis ... its lead development candidate, EDP-239, from its NS5A ...
Cached Medicine Technology:Enanta Enters Into Strategic Collaboration to Advance NS5A Inhibitor Candidate for HCV 2Enanta Enters Into Strategic Collaboration to Advance NS5A Inhibitor Candidate for HCV 3
(Date:8/4/2015)... CA (PRWEB) , ... August 04, 2015 , ... ... Rise of Local Food,” scheduled for Nov. 3 – 4, 2015, at UC ... food sustainably, create new businesses, improve food access, and manage resources efficiently against ...
(Date:8/4/2015)... ... 2015 , ... Many men are confused about the safety of testosterone replacement ... as a voice of authority for men seeking accurate information about testosterone. , ... and expertise in the safe and effective treatment of low testosterone. In recent years, ...
(Date:8/4/2015)... ... August 04, 2015 , ... They say a picture ... certain health conditions, pictures and medical art can be essential. StayWell, a health solutions ... , Krames Patient Education solutions have been used by physicians and other health care ...
(Date:8/4/2015)... ... August 04, 2015 , ... Discovia, a ... today announced that John Munro, a 15-year veteran of the eDiscovery services industry, ... Operations. , “I am thrilled to join Discovia at this important point in ...
(Date:8/4/2015)... CA (PRWEB) , ... August 04, 2015 , ... ... consultation complete with full examination now offered by the world renowned Beverly ... beautiful aesthetic facial appearance through cosmetic surgery techniques helps individuals to achieve an ...
Breaking Medicine News(10 mins):Health News:Diversity of Urban and Hydroponic Farms of the Future to Highlight Seedstock Annual Conference Field Trip 2Health News:Diversity of Urban and Hydroponic Farms of the Future to Highlight Seedstock Annual Conference Field Trip 3Health News:New Video from Renew Man™ Raises Awareness of the Right Way to Correct Low Testosterone 2Health News:New Video from Renew Man™ Raises Awareness of the Right Way to Correct Low Testosterone 3Health News:StayWell Offers Instant Downloads, Licensing of Medical Art to Improve Patient Education 2Health News:StayWell Offers Instant Downloads, Licensing of Medical Art to Improve Patient Education 3Health News:John Munro Joins eDiscovery Leader Discovia as Vice President of Managed Services Operations 2Health News:John Munro Joins eDiscovery Leader Discovia as Vice President of Managed Services Operations 3Health News:Beverly Hills Surgeon, Dr. Paul Nassif, is Now Offering Personal Consultations with Full Examinations for Facial Plastic Surgeries 2Health News:Beverly Hills Surgeon, Dr. Paul Nassif, is Now Offering Personal Consultations with Full Examinations for Facial Plastic Surgeries 3
... Business Coalition on Health releases nationwide eValue8,findings, ... to the eValue8,(TM) report of health plan ... Coalition on Health (NBCH), health plans could ... with their customers, enabling,improvements in patient safety, ...
... Nicotine Cessation Expert and ... Former ... just a,habit; it,s an addiction. Hazelden has been helping alcoholics and ... principles,of the Hazelden treatment experience help tobacco users find recovery, too. ...
... University Hospitals Case Medical Center finds that Deep ... Tourette Syndrome (TS). This first-of-its-kind study of five ... tic frequency and severity in some people who ... is a neurobehavioral disorder characterized by sudden, repetitive ...
... kill them, study finds , , MONDAY, Nov. 12 (HealthDay ... weapons that helps make community-associated methicillin-resistant Staphylococcus aureus ... be done, the study "provides a partial explanation of ... and gives a starting point in the development of ...
... dental mercury uses contribute to high mercury,levels in fish ... first time, that dental mercury air,emissions may be more ... WASHINGTON, Nov.12 The U.S. House,Subcommittee on Domestic ... a hearing on Wednesday, Nov. 14, to discuss FDA,s,responsibility ...
... Gov. Mitch,Daniels joined executives from Medco Health Solutions, ... company,s plans to build the world,s largest and ... growing,nationwide demand for lower-cost medicines. The new 318,000-square-foot,pharmacy, ... an area equivalent to,six and a half football ...
Cached Medicine News:Health News:National Survey Finds Employers are Challenging Health Plans to Better Use Resources to Prevent Illness and Improve Patient Safety 2Health News:National Survey Finds Employers are Challenging Health Plans to Better Use Resources to Prevent Illness and Improve Patient Safety 3Health News:National Survey Finds Employers are Challenging Health Plans to Better Use Resources to Prevent Illness and Improve Patient Safety 4Health News:Quit Smoking Tips For The Great American Smokeout Day - November 15 2Health News:University Hospitals Case Medical Center finds new treatment holds promise for Tourette syndrome 2Health News:University Hospitals Case Medical Center finds new treatment holds promise for Tourette syndrome 3Health News:Key to MRSA Virulence in Community Discovered 2Health News:Key to MRSA Virulence in Community Discovered 3Health News:Environmental Impacts of Dental Mercury Focus of U.S. House Oversight Hearing Wednesday 2Health News:Medco to Build World's Largest, Most Advanced Automated Pharmacy in Central Indiana 2Health News:Medco to Build World's Largest, Most Advanced Automated Pharmacy in Central Indiana 3Health News:Medco to Build World's Largest, Most Advanced Automated Pharmacy in Central Indiana 4Health News:Medco to Build World's Largest, Most Advanced Automated Pharmacy in Central Indiana 5
... Healthcare is known as ... analysis programs for every ... device. With advanced programs ... and ACI-TIPI, GE can ...
... The Affinity pacemaker family ... smallest, truly automatic devices. ... combination of advanced technologies ... DR pacemaker incorporates the ...
... Guidant INSIGNIA Ultra pacing ... easy-to-use features for simplified ... patient safety. All INSIGNIA ... using the ZOOM Programming ...
... SDX model 1688 and model 1488 active-fixation ... pacing leads, offering the unsurpassed handling advantages, ... Medical's line of active-fixation leads. Implantable with ... diameter of the Tendril SDX lead is ...
Medicine Products: