Navigation Links
CuraGen Advances CR011-vcMMAE into Phase II
Date:4/9/2008

- Clinical trial expanded to further evaluate activity of CR011-vcMMAE for

advanced melanoma - - Preliminary Phase I/II results to be presented in June at 2008 ASCO

Annual Meeting -

BRANFORD, Conn., April 9, 2008 /PRNewswire-FirstCall/ -- CuraGen Corporation (Nasdaq: CRGN), a clinical-stage biopharmaceutical company focused on oncology, announced today that it has advanced CR011-vcMMAE, an antibody-drug conjugate (ADC), into Phase II for the treatment of patients with unresectable Stage III and Stage IV melanoma. CuraGen also announced today that updated data from the ongoing Phase I/II trial with CR011-vcMMAE will be presented at the 2008 American Society of Clinical Oncology (ASCO) Annual Meeting, to be held May 30 - June 3, 2008 in Chicago, IL.

"We are pleased with the progress achieved in the CR011-vcMMAE clinical program," commented Dr. Ronit Simantov, Vice President of Medical Development and Chief Medical Officer. "Advancing this program into Phase II is an important development milestone as we look to establish the role of CR011-vcMMAE in the treatment of patients with advanced melanoma."

"Antibodies have made a significant impact in cancer treatment, and we believe that ADCs represent the next generation of antibody technologies. Over the last year, ADCs have demonstrated proof-of-concept activity against both solid tumors and hematologic malignancies," said Dr. Timothy M. Shannon, President and Chief Executive Officer of CuraGen. "We are encouraged by the activity observed to date with CR011-vcMMAE and are looking forward to reporting updated results at ASCO in June."

CR011-vcMMAE is an ADC comprised of a fully-human monoclonal antibody aga
'/>"/>

SOURCE CuraGen Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. CuraGen and TopoTarget Announce Presentations on Belinostat at the Upcoming American Society of Hematology 49th Annual Meeting
2. CuraGen and TopoTarget Announce Presentation of Belinostat Clinical Trial Results at AACR-NCI-EORTC International Conference
3. CuraGen Announces Presentation of Phase I Dose-Escalation Results on CR011- vcMMAE for Metastatic Melanoma
4. CuraGen Announces Top-Line Phase II Results on Velafermin
5. CuraGen and TopoTarget Initiate Phase I/II Clinical Trial of Belinostat (PXD101) Combination Therapy for Acute Myeloid Leukemia
6. CuraGen Provides Update on Velafermin, Belinostat and CR011-vcMMAE Clinical Development Programs
7. Transdel Pharmaceuticals Advances Lead Topical Pain Drug into Phase 3 Program
8. MedImmune Advances Clinical Development of Antibody Targeting Interleukin-9 in Patients with Asthma
9. Financial Results for Full Year 2007: NicOx Significantly Advances Clinical Programs
10. Stem Cell Breakthrough Advances Science Without Ethical Landmines, Says Cardinal
11. Thermo Fisher Scientific Advances Gene-Silencing Technology for Life Sciences Research

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/25/2009)...re/--RegadoBiosciences,aprivatelyheldcompanyleadin...ontrolagents,announcedthatDavidMazzo,PhD,CEOandPre...HealthCareConferenceattheNewYorkPalaceHotelinNewYo...ST)onTuesday,December1andwillincludeanoverviewofth...program,theanticoagulantsystem,REG1.Thehealthcarei...
(Date:11/25/2009)...e-FirstCall/--Abaxis,Inc.(Nasdaq: ABAX ),amedicalp...sissystems,announcedtodaythatClintSeverson,chairma...alPiperJaffrayHealthCareConferenceonWednesday,Dece...eNewYorkPalaceHotelinNewYorkCity. ,, AboutAbax...tablebloodanalysissystemsforuseinanyveterinaryorhu...
(Date:11/25/2009).../--CempraPharmaceuticalsInc.todayannouncedthatPrab...,willpresentatthePiperJaffray21stAnnualHealthCareC...PalaceHotelinNewYorkCity.Dr.Fernandeswillprovidean...programsforthetreatmentofdrug-resistantpathogensin..., Foundedin2006,CempraPharmaceuticalsisaprivatel...
Breaking Medicine Technology:Regado Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference on December 1, 2009 2LA BioMed to honor Emil D Kakkis M D Ph D and LA County Supervisor Don Knabe 58426 1LA BioMed to honor Emil D Kakkis M D Ph D and LA County Supervisor Don Knabe 58426 2Global public health the focus of scientific conference 10144 1Global public health the focus of scientific conference 10144 2Clot Busting Therapy Under Review 58424 1Clot Busting Therapy Under Review 58424 2Clot Busting Therapy Under Review 58424 3
...INACH, Switzerland, October 14 Arpida Ltd.,(SWX: ...from the U.S. Food,and Drug Administration (FDA) t...mittee will discuss the New Drug Application (NDA)...Skin Structure Infections,(cSSSI) during its meeti...an be requested by FDA as part of the review proce...
...w 1.5 million dollar NIH funding advances study ...vival rates, MINNEAPOLIS, Oct. 13 Advanced Circu...ory.com ) announced today that it has received,an ...al Institutes of,Health (NIH) to continue a study ...ho experience cardiac arrest outside a hospital. W...
Other Medicine Technology:Arpida Announces Review of Iclaprim NDA by FDA Advisory Committee in November 2008 2Arpida Announces Review of Iclaprim NDA by FDA Advisory Committee in November 2008 3Whatcom County, Washington Participating in NIH Study of Cardiac Arrest Resuscitation Techniques 2
(Date:11/26/2009)...Ennis & Ennis, P.A. is offering free nationwid...Yasmin birth control pills who have suffered a Dee...e, Heart Attack or other related cardiac issues or...l free at 1-800-856-6405 or go to the firm’s... an online case evaluation form. , ...
(Date:11/25/2009)...Nov.25/PRNewswire-FirstCall/-- OnyxPharmaceutical...illhosttwoinvestoreventsinDecember: ,, ASHBri....ET ,, Principalinvestigatorswilldiscussdatap...refractorymultiplemyeloma,asfeaturedatthe51stAmeri...ioninNewOrleans,LA.Theteleconferencewillbeginat9:0...
(Date:11/25/2009)...ov.25/PRNewswire/--Thanksgivingmealswillbedelivere...ongBeachareathankstoFaithInAction/VolunteerActionf...adivisionofSCANHealthPlan.Formorethan17yearstheseo...verwarmThanksgivingmealstoseniorsinneedinLongBeach...rroundingcities. ,, "Ourwarmholidaymealsaredeli...
(Date:11/25/2009)...5/PRNewswire/--TheBayAreaAirQualityManagementDistr...e Air Alert forThursday,November26,2009whi...lidfuel,bothindoorsandoutdoors. ,, "Cold,stillw..."saidJackBroadbent,executiveofficeroftheAirDistric...theirneighborsandfellowcommunitymembersthisThanksg...
(Date:11/25/2009)...vidence of a statistically significant survival be... estrogen receptor (ER)-positive tumors had high l...8 (ER-alpha S118-P), according to a brief communic... of the National Cancer Institute . , Approximat...xifen. Preclinical studies have shown that ER-alph...
Breaking Medicine News(10 mins):Health News:Ennis & Ennis, P.A. Announces Nationwide Free, Confidential, Consultations For Users Of Yaz And Yasmin Birth Control Pills 2Health News:Ennis & Ennis, P.A. Announces Nationwide Free, Confidential, Consultations For Users Of Yaz And Yasmin Birth Control Pills 3Health News:Onyx Pharmaceuticals Announces December 2009 Investor Events 2Health News:SCAN Employees and Community Volunteers to Help Deliver One Thousand Thanksgiving Meals to Homebound Seniors 2Health News:Winter Spare the Air Alert in Effect for Thursday, November 26, 2009 2
... who suffer from major depression have overstated ...compared to those who do not suffer from depressio...ool of Medicine, had stated in their findings that...sponses to stress in depressed patients might also...
...ents on long-term oxygen therapy for chronic obstr...kely to die from the disease than men.// The... the American Journal of Respiratory and Critical ...ospital of S?o Paulo in Brazil, and seven associat...
...y, a multivitamin pill should be taken daily by al...ing a child with birth defects.// According t...vere birth defects like neural tube defects such a...stically reduced by ensuring an adequate intake of...
...ople are eating and drinking more today at each me...e extra orange juice we consume could add five pou...with the idea of replicating a portion-size study ...lts revealed the following results: -- Orange...
...ded on the effects of junk-food advertising.While ...k food// can still not be expected at any time in ...rnment has made it clear a ban is out of the quest...er. Carter says that a review of studies that c...
...eople living in former industrial towns, like Easi...se.// According to a survey conducted by a cr...Foster Intelligence, the residents of Easington, i...st Midlands were second with 21% more at risk foe ...
Other Medicine News:Health News:Patients With Major Depression Have An Overstated Inflammatory response to Stress 2Health News:Patients With Major Depression Have An Overstated Inflammatory response to Stress 3Health News:Women Are More Likely To Die Than Men When On Oxygen Therapy 2Health News:Prenatal multivitamins reduce birth defects 2Health News:Prenatal multivitamins reduce birth defects 3Health News:Should Junk Food Ads be Banned or Not? 2
SLM 5000 Autolensmeter
...bjective nature of manual lensmeter readings, redu...ctive measurements every time. The easy to read, h...ystem ensure fast and simple operation. On-screen...oning and, in auto mode, users can make a complete...
...gned for fast & easy operation. The 5.7 inch color...ne., ,In AUTO mode, the readings are automatic...-Focal lenses are automatically detected by TL-300...sition the lens. The color touch panel display is ...
KOWA nonmyd 7 / VK-2 Digital Imaging System
Medicine Products: