Navigation Links
CuraGen Advances CR011-vcMMAE into Phase II
Date:4/9/2008

- Clinical trial expanded to further evaluate activity of CR011-vcMMAE for

advanced melanoma - - Preliminary Phase I/II results to be presented in June at 2008 ASCO

Annual Meeting -

BRANFORD, Conn., April 9, 2008 /PRNewswire-FirstCall/ -- CuraGen Corporation (Nasdaq: CRGN), a clinical-stage biopharmaceutical company focused on oncology, announced today that it has advanced CR011-vcMMAE, an antibody-drug conjugate (ADC), into Phase II for the treatment of patients with unresectable Stage III and Stage IV melanoma. CuraGen also announced today that updated data from the ongoing Phase I/II trial with CR011-vcMMAE will be presented at the 2008 American Society of Clinical Oncology (ASCO) Annual Meeting, to be held May 30 - June 3, 2008 in Chicago, IL.

"We are pleased with the progress achieved in the CR011-vcMMAE clinical program," commented Dr. Ronit Simantov, Vice President of Medical Development and Chief Medical Officer. "Advancing this program into Phase II is an important development milestone as we look to establish the role of CR011-vcMMAE in the treatment of patients with advanced melanoma."

"Antibodies have made a significant impact in cancer treatment, and we believe that ADCs represent the next generation of antibody technologies. Over the last year, ADCs have demonstrated proof-of-concept activity against both solid tumors and hematologic malignancies," said Dr. Timothy M. Shannon, President and Chief Executive Officer of CuraGen. "We are encouraged by the activity observed to date with CR011-vcMMAE and are looking forward to reporting updated results at ASCO in June."

CR011-vcMMAE is an ADC comprised of a fully-human monoclonal antibody aga
'/>"/>

SOURCE CuraGen Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. CuraGen and TopoTarget Announce Presentations on Belinostat at the Upcoming American Society of Hematology 49th Annual Meeting
2. CuraGen and TopoTarget Announce Presentation of Belinostat Clinical Trial Results at AACR-NCI-EORTC International Conference
3. CuraGen Announces Presentation of Phase I Dose-Escalation Results on CR011- vcMMAE for Metastatic Melanoma
4. CuraGen Announces Top-Line Phase II Results on Velafermin
5. CuraGen and TopoTarget Initiate Phase I/II Clinical Trial of Belinostat (PXD101) Combination Therapy for Acute Myeloid Leukemia
6. CuraGen Provides Update on Velafermin, Belinostat and CR011-vcMMAE Clinical Development Programs
7. Transdel Pharmaceuticals Advances Lead Topical Pain Drug into Phase 3 Program
8. MedImmune Advances Clinical Development of Antibody Targeting Interleukin-9 in Patients with Asthma
9. Financial Results for Full Year 2007: NicOx Significantly Advances Clinical Programs
10. Stem Cell Breakthrough Advances Science Without Ethical Landmines, Says Cardinal
11. Thermo Fisher Scientific Advances Gene-Silencing Technology for Life Sciences Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... JORDAN, Utah , July 10, 2014  BC ... solutions, and MiE America , Inc., a leading ... have entered into a long-term agreement naming BC Technical ... the US. MiE and BC Technical ... strategic agreement to establish BC Technical as the service ...
(Date:7/10/2014)... July 10, 2014 CVS Caremark Corporation (NYSE: ... has approved a quarterly dividend of $0.275 (27.5 cents) per ... on August 1, 2014, to holders of record on July ... CVS Caremark is dedicated to helping people on their path ... the United States . Through the company,s ...
(Date:1/15/2014)... DUBLIN , Jan. 15, 2014  Research and Markets ... "Dental Consumables Market - Global Industry Analysis, Size, ... report to their offering. (Logo: ... products which are used on patients in order to ...
Breaking Medicine Technology:BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3
... LITTLE FALLS, N.J., March 3, 2011 Cantel Medical Corp. ... its second quarter ended January 31, 2011 on Wednesday, March ... to discuss the results at 11:00 AM ET. Participating in ... Krakauer, President and CEO; Seth R. Segel, Executive Vice President; ...
... ConvaTec Healthcare, a world-leading developer, manufacturer and marketer of ... announced that, recognizing favorable conditions in the credit markets, ... a portion of its senior secured term loans originally ... While the year-end audit process is ongoing, ConvaTec presently ...
Cached Medicine Technology:Cantel Medical Corp. to Hold Conference Call to Discuss Results for Its Second Quarter Ended January 31, 2011 2ConvaTec Healthcare Announces Plans to Refinance Secured Term Loans 2ConvaTec Healthcare Announces Plans to Refinance Secured Term Loans 3
(Date:7/14/2014)... Love Digits LLC has successfully launched ... The App brings ancient astrology to the modern dating ... compatibility using a five-star rating system. By entering their ... test their compatibility for love and marriage across seven ... five-star rating system generates a weighted average of the ...
(Date:7/14/2014)... Spine Team Texas continues to ... to treatment and recovery. Currently all physical therapists at ... training for certification in The McKenzie Method. Two therapists, ... extensive program. , “We require certification of our therapists ... better outcomes for spine pain patients,” said Mark Hood, ...
(Date:7/14/2014)... WA (PRWEB) July 14, 2014 ... solutions, today announced its new IBM i (AS/400, ... Software Vendors (ISVs). As security threats evolve and ... software providers struggle to modernize their applications and ... program now makes it easy for ISVs on ...
(Date:7/14/2014)... Crystal Dental has recently announced that ... has been made via LAD Solutions in in order to ... been made in order to draw in new patients that ... , Crystal Dental offers a variety of services for both ... Crystal Dental include cosmetic dentistry procedures such as porcelain veneers ...
(Date:7/13/2014)... July 14, 2014 Save the Date for ... Hospital in Jacksonville, FL , BOXWOODS & BowTies “A Modern ... , Who: The Women’s Board of Wolfson Children’s Hospital ... Show to continue their ongoing commitment to raising funds ... children. , What: The 2014 Art & Antiques Show ...
Breaking Medicine News(10 mins):Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 3Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3Health News:IBM i ISVs Can Now Easily Integrate Mobile-Based Two Factor Authentication to Increase Security of Solutions 2Health News:IBM i ISVs Can Now Easily Integrate Mobile-Based Two Factor Authentication to Increase Security of Solutions 3Health News:Crystal Dental Announces the Opening of New Office Location in Sacramento 2Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 2Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 3Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 4Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 5Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 6Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 7Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 8Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 9
... , TUESDAY, May 22 (HealthDay News) -- ... C virus could develop potentially life-threatening liver complications over ... Researchers evaluated medical insurance claims data and found ... liver disease in 2008, and estimated that another 300,000 ...
... A novel pancreatic cancer vaccine shows promise in improving survival ... of University Hospitals Case Medical Center,s Seidman Cancer Center and ... data was presented today (embargoed 11:00 am ET) at the ... Tract, part of Digestive Disease Week in San Diego. ...
... Mich. When thousands of psychiatrists attend their field,s ... about research into drug treatments report overwhelmingly on positive ... study published in the Journal of Clinical Psychopharmacology ... Michigan and Yale University, who analyzed the presentations given ...
... 2012) The national gastroenterology societies have issued a ... The Multisociety Sedation Curriculum for Gastrointestinal Endoscopy (MSCGE) ... programmatic approach to the training of procedure sedation. The ... American Journal of Gastroenterology , GIE:Gastrointestinal Endoscopy , ...
... The Food and Drug Administration has approved a new ... disorders. The test, or assay, was developed by an expert ... Lawrence Schwartz, M.D., Ph.D., chair of the Division of ... Professor of Medicine at VCU, has spent more than 30 ...
... the Antwerp Institute of Tropical Medicine, has produced proteins ... can be used in more efficient diagnostic tests, without ... year many thousands of Africans contract sleeping sickness. The ... transmitted by the bite of tsetse flies. First the ...
Cached Medicine News:Health News:Hepatitis C Causing Liver Damage in Greater Numbers: Study 2Health News:Researchers present new findings for novel pancreatic cancer vaccine 2Health News:Bias found in mental health drug research presented at major psychiatric meeting 2Health News:Bias found in mental health drug research presented at major psychiatric meeting 3Health News:Gastroenterology Societies issue sedation curriculum for gastrointestinal endoscopy 2Health News:FDA clears test developed in partnership with VCU researcher 2Health News:Better tests for sleeping sickness 2
... Borrelia (Lyme) test is an ... for the qualitative detection of ... and related Borrelia burgdorferi antibodies ... detected in serum as an ...
... Tests are qualitative enzyme immunoassays (EIA) for ... (IgG or IgM, respectively) in serum. Equivocal ... be supplemented with a standardized western blot ... to support a clinical diagnosis of B. ...
... dot-blot assay system combining microwell EIA and ... antigen set at a clinically meaningful cutoff ... detected using the same reagent system used ... antigens detected in Auto 4 detecting the ...
... The ImmunoWELL Cardiolipin Antibody (IgM) ... (EIA) for the quantitative detection ... in serum and is used ... the risk of thrombosis in ...
Medicine Products: