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CryoLife Provides Update on ValveXchange®, Inc. Investment
Date:10/13/2011

ar may respond differently to the technology than older patients.  The initial human tests have only recently been performed and ultimate results may not meet expectations.  The anticipated timing of additional procedures and testing related to the Vitality Exchangeable Heart Valve System may be delayed due to regulatory restraints and business considerations.  The ability of ValveXchange to successfully distribute the Vitality Exchangeable Heart Valve System worldwide is dependent upon the technology's acceptance by patients and physicians and the marketing efforts of ValveXchange employees and distributors, as well as general global economic conditions.  The benefits of the Vitality Exchangeable Heart Valve System may not ultimately prove to be permanent and the technology may not prove to be as beneficial to patients as expected, if at all.  Also, the related leaflet sets may not last as long as expected and/or they may not retain the expected level of valve function for the entire life of the leaflet sets.  The investment that CryoLife has made in ValveXchange may not be successful and it may take longer than expected for ValveXchange's technology to be accepted in the market and for CryoLife to reap the benefits of its investment in ValveXchange.  Even with CryoLife's investment in ValveXchange, some or all of its products and systems may not be brought to market when expected, if at all.  Business considerations, market forces or regulatory issues may impede distribution efforts.  Regulatory approvals, in particular, are subject to testing results and the discretion of governmental and administrative agents, and there is no guarantee that ValveXchange will obtain the requisite approvals for its products and systems, or that the approval process will not be more time-consuming and costly than expected.  ValveXchange is also subject to the general risks inherent in the medical device sector, including regulatory
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SOURCE CryoLife, Inc.
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Related medicine technology :

1. CryoLife Reports Record Revenues for the Second Quarter and First Six Months of 2011
2. CryoLife Announces Release Date and Teleconference Call Details for 2011 Second Quarter Financial Results
3. CryoLife Makes Equity Investment in ValveXchange® Inc.
4. CryoLife Announces Completion of Acquisition of Cardiogenesis
5. CryoLife Announces Final Results of Tender Offer for 49.9 Percent of the Outstanding Shares of Cardiogenesis Corporation
6. CryoLife Completes Tender Offer for 49.9 Percent of the Outstanding Shares of Cardiogenesis Corporation
7. CryoLife Posts Record Quarterly Revenues of $30.2 Million
8. CryoLife Launches BioGlue® Surgical Adhesive in Japan
9. CryoLife Announces Release Date and Teleconference Call Details for 2011 First Quarter Financial Results
10. CryoLife Announces Expiration of Go-Shop Period Related to its Proposed Acquisition of Cardiogenesis Corporation
11. CryoLife Commences Tender Offer for All Outstanding Shares of Cardiogenesis Corporation
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