Navigation Links
Corthera's Relaxin Receives FDA Fast Track Designation for the Treatment of Acute Heart Failure
Date:10/1/2009

romising safety and efficacy of relaxin seen in these patients. The Pre-RELAX-AHF / RELAX-AHF study was designed and conducted in collaboration with Momentum Research, headed by Dr. Gad Cotter, a noted heart failure expert.

"Patients with acute heart failure remain a major clinical challenge with very high morbidity and mortality rates and limited treatment options," said John R. Teerlink, M.D., Professor of Medicine, University of California San Francisco, Director of Heart Failure, Veterans Affairs Medical Center, San Francisco, and co-principal investigator of the studies. "The importance of this Fast Track designation is two-fold as it acknowledges a significant unmet medical need and recognizes relaxin's potential as an important treatment option for patients with AHF."

According to U.S. data, there are more than 3 million hospital discharges each year with heart failure as a diagnosis, with significant short-term rehospitalization and one-year mortality rates. It is the single largest expense to Medicare, accounting for more than $13 billion in hospitalization costs. The great majority of acute heart failure patients have fluid accumulation in the lungs (congestion) that causes shortness of breath (dyspnea) and other complications. For these patients, the current standard of care includes diuretics and vasodilators. Available agents from both of these classes of agents have been associated with renal impairment, hypotension and adverse outcomes.

About Relaxin

Relaxin is a naturally occurring peptide hormone that acts as a systemic and renal vasodilator. Elevated levels of relaxin modulate increases in renal and cardiac function that meet the increased hemodynamic demands of pregnancy. Consistent with this natural role of the hormone, pharmaceutically manufactured relaxin has been shown to have these effects in multiple human studies of men and non-pregnant women, including patients with heart failure.


'/>"/>
SOURCE Corthera Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Results and Additional Analyses From Study Show That Cortheras Relaxin for Acute Heart Failure is the Strongest Predictor of Improved Longer-Term Outcomes Following Hospital Discharge When Compared to Other Variables
2. Results and Additional Analyses From Efficacy and Safety Study of Cortheras Relaxin in Acute Heart Failure to be Presented at Heart Failure Congress 2009
3. Results From Study Show Promising Efficacy and Safety Results for Cortheras Relaxin in Acute Heart Failure
4. Results From Efficacy and Safety Study of Cortheras Relaxin in Acute Heart Failure to be Presented at Late-Breaking Clinical Trials Session at ACC 58th Annual Scientific Session
5. Corthera Initiates Phase II Clinical Trial of Relaxin in Acute Heart Failure
6. Sigma-Aldrich(R) Receives Award From Michael J. Fox Foundation to Develop Parkinsons Disease Research Models
7. Mylan Receives FDA Approval for Generic Version of Parkinsons Treatment Sinemet(R)
8. GenVec Receives National Cancer Institute Grant to Expand Cancer Program
9. Hologic Receives CE Marking for the ThinPrep(R) Integrated Imager
10. Oxygen Biotherapeutics, Inc. Receives Phase II Trial Approval in Israel
11. Childrens Hospital Receives Six-Year Federal Contract to Study Antibiotic Use in Children With Urinary Tract Infections
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Calif. , Aug. 20, 2014 The National ... Fernando Davila has been successfully treated for a ... by Dr, Anibal R. Gauto , Medical Director of ... at Eisenhower Medical Center in Rancho Mirage, California ... treatment pioneered by Dr. John Crew at Seton ...
(Date:8/20/2014)... , Aug. 20, 2014 Research and ... Report of Pralmorelin" report to their offering. ... providing comprehensive data on Pralmorelin globally and regionally ( ... North America , Latin America ... Pralmorelin This report focuses on three primary areas; ...
(Date:8/20/2014)... DUBLIN , Aug. 20, 2014 ... addition of the "Global Advanced Wound Care ... Geography) - Size, Share, Global Trends, Company Profiles, ... Forecast, 2013 - 2020" report to their ... "Global advanced wound care and closure market (types, ...
Breaking Medicine Technology:Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 2Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 3Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 4Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 5Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 6Global Market Report of Pralmorelin 2Global Advanced Wound Care and Closure Market (Types, Applications, End User and Geography) - Forecast to 2020 2
... 2011 3-V Biosciences, Inc. announced today Stephen R. Brady ... (Logo:   http://photos.prnewswire.com/prnh/20100513/LA04336LOGO ) "Steve,s contributions have been ... at 3-V," said Merdad V. Parsey, MD, PhD, 3-V,s Chief ... we continue to build the 3-V team and advance the ...
... 2011 Awarepoint Corporation today announced it conducted its ... and User Group , Viewpoint | 2011, January 23-25, ... http://photos.prnewswire.com/prnh/20100127/LA44915LOGO ) At this exclusive Awarepoint event, ... with other hospitals to share information and use cases ...
Cached Medicine Technology:3-V Biosciences Promotes Stephen R. Brady to Chief Business Officer 2Awarepoint Announces First Annual RTLS Customer Conference and User Group Results and Highlights 2Awarepoint Announces First Annual RTLS Customer Conference and User Group Results and Highlights 3Awarepoint Announces First Annual RTLS Customer Conference and User Group Results and Highlights 4
(Date:8/20/2014)... 2014 (HealthDay News) -- A new study found no ... treatment for high blood pressure increases patients, risk of ... high blood pressure can prevent strokes and other cardiovascular ... high blood pressure may lead to low blood pressure, ... They looked at about 3,100 patients, aged 40 ...
(Date:8/20/2014)... 20, 2014 Get the report here: ... mergermarket presents ‚ÄúDeal Drivers 2014 Half Year Report for ... M&A activity in both North and South America, with ... About Merrill DataSite     , Merrill DataSite is a ... the due diligence process by providing a highly efficient ...
(Date:8/20/2014)... Beach, Florida (PRWEB) August 20, 2014 ... Florida, with the help of their experienced surgeons trained ... of patients to regain their lost or inaccurate vision. ... for performing Lasik surgery is making it possible for ... aging disease which occurs normally in people in the ...
(Date:8/20/2014)... The award-winning plastic surgery group, The Aesthetic ... throughout Houston to a third office, located in Katy, ... building. ACPS plastic surgeon Dr. Rolando Morales said the ... has risen to become one of the largest, most ... since its establishment in 1996 by plastic surgeons Dr. ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 According ... Market Research "Multiplexed Diagnostics Market (Technologies: Very High, ... Applications: Infectious Disease Diagnosis, Oncology, Autoimmune Diseases, Cardiac, ... Share, Growth, Trends and Forecast, 2013 - 2019", ... USD 2.8 billion in 2012 and is expected ...
Breaking Medicine News(10 mins):Health News:Tight Blood Pressure Control Doesn't Raise Risk of Falls, Study Says 2Health News:Register to Download Merrill DataSite's Report: Deal Drivers 2014 Half Year Report for the Americas 2Health News:Braverman Eye Center Now Offers Multifocal PresbyLasik in Florida by Trained Surgeons 2Health News:Aesthetic Center for Plastic Surgery Expands Its Reach in Texas 2Health News:Multiplexed Diagnostics Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 2Health News:Multiplexed Diagnostics Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 3Health News:Multiplexed Diagnostics Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 - 2019 4
... efforts beginning as evacuees leave coastal areas, WASHINGTON, ... Gulf Coast states, the American Red Cross is starting ... Red Cross has relief,operations ready in four states: Alabama, ... storm is urged to prepare, listen to officials,and heed ...
... release is available in Spanish . ... psychiatric diseases, often associated with considerable treatment needs and ... and family (Pini et al., 2005). Previously also labelled ... an episodic, yet lifelong and clinically severe mood (or ...
... found telmisartan offered slight benefit for those unable to ... -- A new study offers a possible alternative to ... blood pressure under control but who cannot tolerate the ... European Society of Cardiology in Munich on Sunday, Canadian ...
... August 31, 2008 -- An international study led by ... to lower blood pressure, reduced the outcome of cardiovascular ... unable to tolerate a widely available and effective standard ... in the Michael G. DeGroote School of Medicine at ...
... Aug. 31, 2008 Many nursing mothers who ... the "superbug" methicillin-resistant Staphylococcus aureus , or MRSA, ... Center physicians, conservative treatment can deal with the problem. ... mastitis, and showed that MRSA was much more likely ...
... Council (ACC) applauds the California Assembly for listening ... bill that would have,needlessly removed safe and essential ... containing bisphenol A has been recently,reaffirmed by scientific ... legislators made the right decision for their consumers,",stated ...
Cached Medicine News:Health News:American Red Cross Relief Efforts Underway for Gustav 2Health News:The ECNP consensus statement on bipolar depression 2Health News:The ECNP consensus statement on bipolar depression 3Health News:The ECNP consensus statement on bipolar depression 4Health News:The ECNP consensus statement on bipolar depression 5Health News:Newer Blood Pressure Drug Better for Some Heart Patients, Diabetics 2Health News:Global study shows telmisartan reduces outcome of cardiovascular death, heart attack or stroke 2Health News:'Superbug' breast infections controllable in nursing mothers, UT Southwestern researchers find 2Health News:ACC Applauds California's Decision to Not Ban Food-Contact Products Containing Bisphenol A 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: