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Continuous Treatment With Abbott's HUMIRA(R) Achieves Superior Long-Term Efficacy for Psoriasis Patients Compared to Interrupting Treatment
Date:9/18/2008

idence for physicians and patients regarding HUMIRA's ability to clear the frequently-painful skin lesions associated with psoriasis," said Rebecca Hoffman, M.D., divisional vice president, Immunology, Abbott. "Abbott is committed to continuing research into HUMIRA's optimal use in psoriasis and other therapeutic areas."

About the REVEAL Trial

The REVEAL study was a 52-week, double blind, randomized, placebo-controlled Phase III trial to evaluate the efficacy and safety of HUMIRA in 1,212 patients with moderate to severe chronic psoriasis in the United States and Canada.

About Psoriasis

Psoriasis affects an estimated 125 million people worldwide. The severity of the disease varies from person to person with approximately 25 percent of people with psoriasis experiencing moderate to severe disease.

Psoriasis can develop anywhere on the skin and most commonly appears on the scalp, knees, elbows, lower back, hands and feet. It may even occur in the fingernails and toenails. While psoriasis occurs in people of all ages, it typically first appears in people between the ages of 15 and 25.

Psoriasis can be a very isolating disease and people with psoriasis may suffer from poor self-image, depression and an increased risk of premature death.

Important Safety Information

Globally, prescribing information varies; refer to the individual country product label for complete information.

Serious infections, sepsis, rare cases of tuberculosis (TB), and opportunistic infections, including fatalities, have been reported with the use of TNF antagonists, including HUMIRA. Many of the serious infections have occurred in patients on concomitant immunosuppressive therapy that, in addition to their underlying disease could predispose them to infections. Patients must be monitored closely for infections, including tuberculosis, before, during and after treatment with HUMIRA. Treatment should not be initiated in patients with act
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