Navigation Links
Continued Funding to Help Advance 'Exciting Moment' in Diabetes Research

American Diabetes Association and Richard and Susan Smith Family Foundation Announce Renewed Commitment to Diabetes Gene Study

ALEXANDRIA, Va., April 30 /PRNewswire-USNewswire/ -- The American Diabetes Association (ADA) has announced research projects to study newly discovered human type 2 diabetes genes in mice, and potentially find new drug molecules that can treat the genetic causes of type 2 diabetes. The projects will be funded through a renewed partnership -- between the ADA/Richard and Susan Smith Family Foundation Pinnacle Program Project Award -- of more than $2 million over three years.

Evan Rosen, MD, PhD, of Beth Israel Deaconess Medical Center in Boston, and Vamsi K. Mootha, MD, of Harvard University are lead researchers for the grant projects. Dr. Rosen's study Humanized Mouse Models of Type 2 Diabetes will focus on whether mouse models with human diabetes genes will have beneficial effects on glucose control. Dr. Mootha's project Cellular Models of Human Type 2 Diabetes Genes will study whether markers can be established to monitor therapeutic responses. This grant will expand on the foundation that the first Pinnacle Program Project, Systematic identification of pathways contributing to diabetes and obesity, set forth.

Research from the Foundation's initial grant led to the discovery of five new genes associated with type 2 diabetes, as well as one for obesity and one for triglyceride levels (a component of blood cholesterol). The discoveries were found with the use of a new and powerful approach to diabetes research developed based on contributions by the group, whole genome association studies (WGAS).

"The discoveries of these researchers have contributed greatly to our knowledge of genes influencing diabetes and to a lesser extent obesity," commented Cathy Bernstein, Chair, ADA Research Foundation. "The novel genes identified by this approach were completely unexpected from previous knowledge, and have opened up new windows into the biology of these diseases."

"This is a truly exciting moment, with great possibilities for building and expanding on these successes," commented Scott Campbell, ADA Vice President of Research. "These newly discovered genes provide leads that must be followed to decipher the causes of type 2 diabetes and to obtain clues for improving prevention and treatment."

The Richard and Susan Smith Family Foundation Pinnacle Program Project Award was established to stimulate new collaborations among investigators working on independent but complementary research projects aimed at developing methods of preventing type 2 diabetes.

About the American Diabetes Association

The American Diabetes Association is the nation's premier voluntary health organization supporting diabetes research, information and advocacy. Founded in 1940, the Association has offices in every region of the country, providing services to hundreds of communities. The Association's commitment to research is reflected through its scientific meetings; education and provider recognition programs; and its Research Foundation and Nationwide Research Program, which fund breakthrough studies looking into the cure, prevention, and treatment of diabetes and its complications. The American Diabetes Association Research Foundation was created to raise support for diabetes research conducted within the Nationwide Research Program. One hundred percent of all Research Foundation contributions go directly to diabetes research. All non-research costs associated with the Research Program are paid for through the Association's general fund.

For more information, please visit or call 1-800-DIABETES (1-800-342-2383). Information from both these sources is available in English and Spanish.

SOURCE American Diabetes Association
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months
2. FDA Advisory Committees Recommend Continued U.S. Marketing Authorization for Trasylol(R)
3. Facet Solutions Enjoys Continued Clinical Success With the Anatomic Facet Replacement System (AFRS(TM))
4. Abbotts XIENCE(TM) V Everolimus Eluting Coronary Stent Shows Continued Superiority to TAXUS Stent in Reducing Major Adverse Cardiac Events in SPIRIT III Clinical Trial
5. Raven Announces Continued Enrollment of Phase 1/2a Clinical Trial of RAV12 Therapeutic Antibody for Treatment of Adenocarcinomas
6. New Trial Presented at AAAAI Reports that the Growth of Children 2-5 Years Old with Year-Round Allergic Rhinitis Continued According to Normal Age-Adjusted Distribution Over a 6-Month Treatment with Nasacort AQ
7. Federal Funding Awarded to Test Antimicrobial Properties of Copper Metals
8. Prostate Cancer Treatment Centre Receives Funding for Clinical Trials
9. U.S. Department of Health and Human Services Completes Funding of 2006 Contract Award to CSCs DVC and Baxter
10. amfAR Announces Funding for HIV Services and Research Aimed at Men Who Have Sex With Men in Developing Countries
11. NanoBio(R) Corporation Completes $30 Million in Equity Funding by Meeting Key Development Milestones
Post Your Comments:
(Date:11/24/2015)... November 25, 2015 The hope ... repeated failure of IVF cycles. After failure of over ... and had lost all hopes that she would be able to conceive ever. ... child conceived after failure of over 15 IVF cycles. ... before they decided to take one last attempt with Gaudium IVF ...
(Date:11/24/2015)... 2015  Thanks to a donor with a personal ... Center,s Sister Diane Grassilli Center for Women,s Health now ... San Francisco . Fred ... with a gift of $617,320 that allowed the Center ... Tomosynthesis and Whole Breast Ultrasound. Tomosynthesis, three-dimensional (3-D) mammography ...
(Date:11/24/2015)... Colo. , Nov. 24, 2015  Array ... that its Chief Executive Officer, Ron Squarer ... Healthcare Conference in New York.  The public is ... webcast on the Array BioPharma website.Event:Piper Jaffray Annual ... , Wednesday, December 2, 2015Time:1:30 p.m. Eastern Time ...
Breaking Medicine Technology:
(Date:11/25/2015)... ... ... In an ongoing Clinical Study conducted by an independent physician, Andrew Gostine, ... evaluating the efficacy of its product and its disinfection protocol. This study is taking ... 2014 through October 2015 at a 360-bed, acute-care, academic medical center located in Chicago, ...
(Date:11/25/2015)... Silver Spring, Md (PRWEB) , ... November 25, ... ... the Pulmonary Hypertension Association (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups ... the history of this disease. The Periwinkle Pioneers, nominated by the public, will ...
(Date:11/25/2015)... ... November 25, 2015 , ... Many people know of the ... gain, cold hands, and dry skin. But many people who find their cholesterol levels ... regimen instead of their thyroid, especially if they don’t have any of the other ...
(Date:11/25/2015)... ... November 25, 2015 , ... Bunion Bootie , ... early celebration of the early holiday shopping season. Starting Wednesday November 25th, Bunion ... ea). Black Friday promotional pricing is in addition to any automatic discounts applied ...
(Date:11/24/2015)... ... , ... New patients who wish to seek treatment for missing teeth can ... her Mississauga, ON practice. Dr. Williams has been providing dental service for over 34 ... Missing teeth can lead to a variety of complications if they are not replaced ...
Breaking Medicine News(10 mins):