Colesevelam HCl Lowered LDL Cholesterol in Pediatric Patients With Heterozygous Familial Hyperchole...(crease (2.3 percent). The most frequentl...),Health

Date:11/11/2008

crease (2.3 percent). The most frequently reported adverse reactions during the additional 18-week open-label treatment period were similar to those during the double-blind period and also included upper respiratory tract infection (4.9 percent), influenza (3.8 percent) and nausea (3.8 percent). Colesevelam HCl was not observed to have an effect on growth, sexual maturation, hormone levels or fat-soluble vitamin levels during the course of the study.

IMPORTANT INFORMATION ABOUT WELCHOL(R) (colesevelam HCl)

Prescription Welchol lowers LDL or "bad" cholesterol in adults, along with diet and exercise. It can be taken alone or with other cholesterol-lowering medications known as statins.

Welchol, along with diet and exercise, also lowers blood sugar levels in adults with type 2 diabetes mellitus when added to other antidiabetic medications (metformin, sulfonylureas, or insulin).

Ask your doctor if Welchol is right for you.

Welchol is not for everyone, especially those with intestinal blockage, those with blood triglyceride levels of greater than 500 mg/dL, or a history of pancreatitis (inflammation of the pancreas) due to high triglyceride levels.

Welchol has not been determined to prevent heart disease or heart attacks.

Tell your doctor if you have high triglycerides (greater than 300 mg/dL).

Tell your doctor if you have stomach or intestinal problems, including gastroparesis (when the stomach takes too long to empty its contents), abnormal contractions of the digestive system, major gastrointestinal tract surgery, or if you have trouble swallowing.

Tell your doctor if you have vitamin A, D, E, or K deficiencies.

Welchol has known interactions with glyburide (a drug for diabetes), levothyroxine (a drug used to treat an underactive thyroid) and certain oral contraceptives. Welchol has not been studied with all combinations of drugs and supplements. Please tell your doctor about all medications and sup
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SOURCE Daiichi Sankyo, Inc. (DSI) Copyright©2008 PR Newswire. All rights reserved

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