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Cogentus to Launch Phase III Program of Novel Combination Product Designed to Reduce Bleeding Side Effect of Antiplatelet Therapy
Date:11/15/2007

ompton Hospital and Professor of Clinical Cardiology at Imperial College. "The gastrointestinal toxicity from dual antiplatelet therapy can result in patients skipping or stopping their treatment altogether," continued Dr. Fox. "Even a short discontinuation of therapy in patients who have recently had a drug eluting stent inserted can result in a heart attack. Clearly there is a need for a safer treatment option."

Recent clinical trial data documenting these side effects have begun focusing attention on the incidence and significance of bleeding associated with antiplatelet medicines.

"Our goal is to improve the safety and tolerability of antiplatelet therapy by significantly reducing gastrointestinal adverse events, including bleeding, to help patients stay on their intended antiplatelet treatment," said Mark A. Goldsmith, M.D., Ph.D., President and Chief Executive Officer of Cogentus Pharmaceuticals. "We believe CGT-2168 may be a significant advance that will preserve and extend the cardiovascular benefits of antiplatelet therapy."

Phase III trials are the last stage of clinical testing required by the U.S. Food and Drug Administration. Successful Phase III studies allow a company to file a New Drug Application with the FDA for approval to market a new medicine.

Physicians and patients interested in obtaining more information about COGENT should go to http://www.clinicaltrials.gov.

ABOUT COGENTUS

Cogentus Pharmaceuticals, Inc., of Menlo Park, CA, is a privately held specialty pharmaceutical company founded in 2006. Cogentus (http://www.cogentus.net) is committed to becoming a premier developer of innovative, fixed-dose combination prescription medicines serving unmet medical needs that drive significant commercial opportunities.

Plavix(R) is a registered trademark of Sanofi-Aventis.


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SOURCE Cogentus Pharmaceuticals, Inc.
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