Navigation Links
Cogentus to Launch Phase III Program of Novel Combination Product Designed to Reduce Bleeding Side Effect of Antiplatelet Therapy
Date:11/15/2007

COGENT Trials To Enroll 4,000 Patients Worldwide

MENLO PARK, Calif., Nov. 15 /PRNewswire/ -- Cogentus Pharmaceuticals, Inc. announced today it is launching a global Phase III clinical program to evaluate the efficacy and safety of its novel combination therapy CGT-2168. The program, which includes the COGENT-1 and COGENT-2 trials, will enroll over 4,000 patients at hundreds of sites in the United States, Canada, Europe and South America.

(Logo: http://www.newscom.com/cgi-bin/prnh/20071112/COGENTUSLOGO)

CGT-2168 is a unique once-daily pill that combines the antiplatelet agent clopidogrel (currently marketed by Bristol-Myers Squibb Co. and Sanofi-Aventis as Plavix(R)) with a gastroprotectant (omeprazole). The product is designed to significantly reduce the gastrointestinal side effects commonly associated with antiplatelet therapy.

COGENT stands for the Clopidogrel and the Optimization of Gastrointestinal Events Trial. The COGENT trials are designed to measure the incidence of upper gastrointestinal bleeding and ulcers in patients who take CGT-2168 and aspirin compared with patients who take clopidogrel and aspirin. The vast majority of patients who take clopidogrel also take aspirin.

Antiplatelet therapy is an integral part of treating patients with cardiovascular disease, including acute coronary syndrome, and has been shown to be effective in preventing major cardiovascular events. However, treatment with antiplatelet medicines such as clopidogrel, aspirin or the frequent combination of the two is associated with gastrointestinal bleeding, which in some cases can require hospitalization and even result in death.

"The benefits of antiplatelet therapy are well established, but the risk of bleeding associated with these treatments has been greatly under-appreciated," said Kim Fox, M.D., F.R.C.P., Director of Cardiology at Royal Br
'/>"/>

SOURCE Cogentus Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Iomai Launches Phase 1/2 Safety Study of Dose-Sparing Patch for Use With Pandemic Influenza Vaccine
4. Keeping the Data Center Clean: ATEN Launches Industry-First KVM Switches with Antimicrobial Nanocoating to Protect Products from Bacteria Surviving on Surfaces
5. Cell Therapeutics, Inc. (CTI) Launches Phase III Study for Pixantrone in Relapsed Indolent Non-Hodgkins Lymphoma (NHL)
6. Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
7. Strategic Diagnostics Launches Initial Oncology-Targeted Antibody Reagent Catalog
8. deCODE Launches Phase II Clinical Testing of DG051 for the Prevention of Heart Attack
9. Premier Micronutrient Launches Supplement for Hearing Health
10. deCODE Launches deCODE MI(TM) -- A Test for a Major Genetic Risk Factor for Early-onset Heart Attack
11. Actress and New Mom Keri Russell Joins PKIDs to launch Silence the Sounds of Pertussis Campaign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... Medical, Inc. (Nasdaq: NXTM ), a leading manufacturer ... Burbank , Chief Executive Officer, and Mathew Towse , ... Annual Canaccord Genuity Growth Conference being held at the InterContinental ... 13 th at 4:30 p.m. ET.  A webcast of ... About NxStage Medical NxStage Medical, ...
(Date:8/1/2014)... , Aug. 1, 2014  Neuland Laboratories Ltd., ... active pharmaceutical ingredients (APIs), complex intermediates and ... in 85 countries, today announced financial results for ... ended June 30, 2014. "Neuland,s results ... flow re-prioritization to accommodate certain customer needs, and ...
(Date:8/1/2014)... Aug. 1, 2014 Dyadic International, Inc. ("Dyadic") ... proprietary technologies are used to develop, manufacture and sell ... biopharmaceutical and industrial enzyme industries, announced today that it ... ended June 30, 2014 after market close on Thursday, ... that day at 5:00 p.m. Eastern Time to discuss ...
Breaking Medicine Technology:NxStage to Present at the 34th Annual Canaccord Genuity Growth Conference 2Neuland Labs Reports First Quarter Fiscal Year 2015 Financial Results 2Neuland Labs Reports First Quarter Fiscal Year 2015 Financial Results 3Dyadic International To Announce Second Quarter 2014 Financial Results And Host Conference Call On Thursday, August 14, 2014 2Dyadic International To Announce Second Quarter 2014 Financial Results And Host Conference Call On Thursday, August 14, 2014 3
... Second Generation Oxazolidinone Demonstrates Safety and Efficacy with Once-Daily, ... of Treatment , , SAN DIEGO, June ... its Phase 2 clinical trial evaluating the safety and ... the treatment of severe complicated skin and skin structure ...
... sets to be released-- , , PARIS, ... in patients with blepharospasm and cervical dystonia -- one placebo-controlled ... presented at the Movement Disorder Society (MDS) 13th annual International ... Pharmaceuticals, which plans to file a Biologic License Application (BLA) ...
Cached Medicine Technology:Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections 2Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections 3Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections 4Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting 2Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting 3Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting 4
(Date:8/1/2014)... The brain plays a central role in regulating appetite ... important in the brain,s control of food intake and ... this process has been unclear. A new ... demonstrates that PPARγ activity in a type of neuron ... the response to high-fat diet. Sabrina Diano and ...
(Date:8/1/2014)... HealthDay Reporter FRIDAY, Aug. 1, 2014 (HealthDay ... may have significantly less endurance than those who weigh less, a ... half were obese, half were of normal weight -- people who ... longer. Obesity also was associated with less strength, increased discomfort ... 50 to 65 years of age -- neither improved nor reduced ...
(Date:8/1/2014)... U.S. Food and Drug Administration announced on Friday that ... type 2 diabetes. Jardiance (empagliflozin) "can be ... control blood sugar levels in the overall management of ... Drug Evaluation II in the FDA,s Center for Drug ... The FDA also recommended that Jardiance be used along ...
(Date:8/1/2014)... a first-of-its-kind study, researchers at University Hospitals Rainbow Babies ... may be at greater risk for death on a ... on flights worldwide between January 2010 and June 2013 ... under the age of 2. , The study ... rare event of an in-flight pediatric fatality onboard commercial ...
(Date:8/1/2014)... August 01, 2014 Summer is here, and ... active during the summer, and they can be a pain ... ready to help all their customers get rid of ticks ... and 6,000 eggs in the summer, which is why they ... in tall grass and woodland areas and carry a number ...
Breaking Medicine News(10 mins):Health News:Obesity Might Slow You Down at Work 2Health News:Obesity Might Slow You Down at Work 3Health News:FDA Approves New Type 2 Diabetes Drug 2Health News:New research characterizes in-flight pediatric deaths 2Health News:Tis the Season for Tick Prevention 2
... ROCM ) will announce quarterly results after,financial markets ... hold a quarterly conference call to discuss its earnings ... (5:00 p.m. eastern time)., This call is being ... website at http://www.rocm.com . To listen live to ...
... China, Oct. 28 /Xinhua-PRNewswire-FirstCall/ -- China Sky ... "the Company") (Nasdaq: CSKI ), a,leading ... the People,s Republic of China ("PRC"), announced ... purchase a proprietary breast drug from,Harbin Medical ...
... The Los Angeles Shambhala Center,presents a public talk and Zen ... 30 and November 1st and 2nd., This 20th generation ... the first time in Los Angeles at the Shambhala Meditation ... Colorado Blvd.,in Eagle Rock., On Thursday, October 30th, Shibata ...
... 28 /PRNewswire-FirstCall/ - Response Biomedical,Corporation (TSX: RBM, OTCBB: ... an initial closing of the financing announced on ... raising gross proceeds of $4.66,million. The closing involved ... at a price of $0.15 for each unit. ...
... series, Debating Health: Election 2008, the Harvard Public Opinion Research ... Harris Interactive conducted a new survey focused on whether voters ... great deal of difference" in the state of the nation,s ... been made of voter cynicism in recent times, a majority ...
... that was 29 days or older faced twice the risk ... receive a transfusion of stored blood that is 29 days ... more serious infections compared to those who get "fresher" blood, ... current U.S. regulations set the upper limit for blood storage ...
Cached Medicine News:Health News:Rochester Medical Announces Fourth Quarter 2008 Earnings Conference Call November 6, 2008 2Health News:China Sky One Medical, Inc. Acquires Drug to Treat Breast Lesions 2Health News:China Sky One Medical, Inc. Acquires Drug to Treat Breast Lesions 3Health News:Renowned Kyudo (Zen archery) Master Kanjuro Shibata Sensei to Present in L.A. 2Health News:Response Biomedical Completes Initial Closing of an expected $5.0 Million Financing 2Health News:Response Biomedical Completes Initial Closing of an expected $5.0 Million Financing 3Health News:Response Biomedical Completes Initial Closing of an expected $5.0 Million Financing 4Health News:Majority of voters say election outcome will make a great deal of difference on key issues 2Health News:Majority of voters say election outcome will make a great deal of difference on key issues 3Health News:Older Blood Boosts Chances of Infection in Transfusion Patients 2Health News:Older Blood Boosts Chances of Infection in Transfusion Patients 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: