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Clinical Trial Results on the Sleep-Promoting Effects of Vanda Pharmaceuticals' Circadian Regulator Tasimelteon (VEC-162) Published in The Lancet
Date:12/1/2008

simelteon (VEC-162) for transient insomnia after sleep-time shift: two randomized controlled multicentre trials." www.thelancet.com. 2008.

(2) Cardinali, Daniel P.; Golombek, Diego A. "Let There Be Sleep - On Time." Letter. www.thelancet.com. 1 December 2008.

(3) Bunney, Jennifer N.; Potkin, Steven G. "Circadian abnormalities, molecular clock genes and chronobiological treatments in depression." British Medical Bulletin. 2008; 86 (1): 23-32.

(4) Perez-Lloret, Santiago; Garcia Aguirre, Alejandro; Cardinali, Daniel P.; Toblli, Jorge E. "Disruption of Ultradian and Circadian Rhythms of Blood Pressure in Nondipper Hypertensive Patients." Hypertension. 2004; 44: 311-315.

(5) Colten, Harvey R.; Altevogt, Bruce M. Institute on Medicine. Committee on Sleep Medicine and Research. Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem. 2006.


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SOURCE Vanda Pharmaceuticals Inc.
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