Navigation Links
Clinical Data from NewLink Genetics' HyperAcute Prostate Cancer Immunotherapy Published in Journal of Immunotherapy
Date:12/13/2012

AMES, Iowa, Dec. 13, 2012 /PRNewswire/ -- NewLink Genetics Corporation (Nasdaq: NLNK) today announced that the results of a  Phase 1 dose escalation study with its proprietary HyperAcute Prostate Cancer Immunotherapy were published in the Journal of Immunotherapy.  The article, entitled "Cellular Immunotherapy Study of Prostate Cancer Patients and Resulting IgG Responses to Peptide Epitopes Predicted From Prostate Tumor-associated Autoantigens," is featured in the current edition of the Journal.

The study was conducted at the University of Nebraska Medical Center and included eight patients.  Patients were scheduled to receive a priming dose on day one, followed by eleven boost doses every two weeks and patients received up to 12 intradermal vaccinations at doses ranging from 30 million to 500 million cells per injection. Patients were tested for safety, immunological and clinical responses arising after immunotherapy.  

The study demonstrated that the immunotherapy was safe, and that the first immunization differentially increased the anti-alphaGal IgG response in all patients compared with baseline levels. These data indicated that administration of HyperAcute-Prostate immunotherapy increases the immune response against alphaGal epitopes, demonstrating the immunogenicity of the vaccine in prostate cancer patients.

The patients that received the highest dose of immunotherapy developed antibody responses against prostate tumor-associated antigens that were not seen in a control group of untreated volunteers.  Data  demonstrated that 37.5 percent (3/8) of patients responded with Prostate Specific Antigen (PSA) level stabilization for more than 100 days.  

The adverse events data reported in this publication confirm the safety of this immunotherapy, consistent with previous studies on the safety of alph
'/>"/>

SOURCE NewLink Genetics Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Clinical Trial at Evergreen Healthcare Shows Intestinal Gel Reduces Symptoms of Advanced Parkinsons Disease
2. Asubio Initiates Landmark Clinical Study in Spinal Cord Injury
3. Pressure BioSciences, Inc. and Target Discovery, Inc. Expand Strategic License Agreement and Collaboration Supporting TDIs Planned Offering of Personalized Medicine Clinical Diagnostic Services
4. AtheroNova Signs Agreement for Development of Clinical Trial Supplies
5. Southern Research Signs Agreement with Apath, LLC to Conduct Preclinical Studies with Virus-Based HCV Screenings
6. Varian Medical Systems and Siemens Healthcare Announce Global Collaboration to Advance Clinical Capabilities and Offerings in Radiotherapy and Radiosurgery
7. New Clinical Endocrinology Guidelines Support Lp-PLA2 Measurement For Risk Assessment of Coronary Artery Disease
8. First Patient Treated in U.S. Clinical Study of Cohera Medicals TissuGlu® Surgical Adhesive
9. Michael J. Fox Foundation-Funded Study Identifies Best Dyskinesia Clinical Rating Scale
10. Oxford BioTherapeutics Appoints Senior Industry Leader to Head its New Clinical Development Operations in Basel, Switzerland
11. Lexicon Pharmaceuticals Reports On Clinical Program Status And 2012 First Quarter Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... , Oct. 1, 2014   Cypher Genomics, Inc., ... of J. Patrick Ravenel as chief technology ... software and systems experience and a proven track record ... "Patrick has been recognized as a ... systems and is known industry-wide for delivering innovative products ...
(Date:10/1/2014)... Mass. , Oct. 1, 2014   ... AEX: PHIA) today announced its eCareCoordinator and eCareCompanion ... U.S. Food and Drug Administration (FDA). A part ... telehealth programs , eCareCoordinator and eCareCompanion are focused ... the first clinical applications to be available through ...
(Date:10/1/2014)... R.I. , Oct. 1, 2014  CVS Health ... Month for their role in changing the way health ... improve quality in the Company,s retail pharmacies, mail service ... month, we changed our company name to CVS Health ... expertise in driving the innovations needed to shape the ...
Breaking Medicine Technology:Cypher Genomics Appoints J. Patrick Ravenel Chief Technology Officer 2Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 2Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 3Philips Secures 510(k) Clearance to Market the First Clinical Applications for its new Digital Health Platform 4CVS Health Thanking its Pharmacists during American Pharmacists Month for Helping People on Their Path to Better Health 2CVS Health Thanking its Pharmacists during American Pharmacists Month for Helping People on Their Path to Better Health 3
... Further data shows PegIFN-λ,s ... New data presented at the International ... revolution in HCV treatment. The much anticipated data from ... combinations of antivirals offer the hope of shorter, more ...
... On Thursday, April 19, 2012, at 8:30 a.m. Eastern/2:30 ... Inc.,s (CTI) (NASDAQ and MTA: CTIC) management team will ... Numbers Thursday, April 19 8:30 a.m. ... (US Participants) 1-480-629-9692 (International) Call-back numbers for ...
Cached Medicine Technology:New Data Suggests Interferon-Free Therapy Around the Corner for HCV Patients 2New Data Suggests Interferon-Free Therapy Around the Corner for HCV Patients 3New Data Suggests Interferon-Free Therapy Around the Corner for HCV Patients 4New Data Suggests Interferon-Free Therapy Around the Corner for HCV Patients 5New Data Suggests Interferon-Free Therapy Around the Corner for HCV Patients 6New Data Suggests Interferon-Free Therapy Around the Corner for HCV Patients 7
(Date:10/1/2014)... 01, 2014 Marriagelifeinsurance.com has released ... insurance for retired couples. , Senior citizens can ... security for their loved ones. A joint policy is ... persons pass away. , Life insurance can be ... insurance can even be purchased online, as the application ...
(Date:10/1/2014)... 01, 2014 First Warning Systems, a ... cellular changes throughout the body, announced the company is ... address the company’s breadth of upcoming product releases. The ... screening technology. , “Our initial focus will be an ... detects abnormal circadian cellular changes over time,” said Rob ...
(Date:10/1/2014)... Join the more than 80 golfers who already have ... charity golf tournament to benefit Project HEAL, a not-for-profit organization ... afford treatment. The tournament will be held Monday, Oct. 6, ... The day-long event starts with 10:30 a.m. check-in and shotgun ... begin at 5 p.m. and will include an auction featuring ...
(Date:10/1/2014)... Innovations announces the upcoming airing of Innovations ... October 20, 2014 at 7:30 a.m. EST/PT via Discovery ... the scenes to learn about Break the Cycle’s comprehensive ... practical help and information Break the Cycle provides to ... of abuse, how to navigate the legal system, and ...
(Date:10/1/2014)... Scientists at the University of Western Australia ... system proteins has the power to knock out mesothelioma ... the new study on their website. Click here ... the UWA School of Pathology and Laboratory Medicine administered ... mesothelioma with promising results. , “A timed triple ...
Breaking Medicine News(10 mins):Health News:Elderly Life Insurance - Find Life Insurance for Retired Couples! 2Health News:First Warning Systems Changes Name to Cyrcadia Health to Better Reflect Core Competency and Goals of Company 2Health News:First Warning Systems Changes Name to Cyrcadia Health to Better Reflect Core Competency and Goals of Company 3Health News:First Warning Systems Changes Name to Cyrcadia Health to Better Reflect Core Competency and Goals of Company 4Health News:Project HEAL Benefit Golf Tournament Gaining Momentum 2Health News:Project HEAL Benefit Golf Tournament Gaining Momentum 3Health News:Innovations to Explore Breakthroughs in Health and Wellness in Upcoming Episode Airing Monday, October 20, 2014 via Discovery Channel 2Health News:New Mesothelioma Study Says Mice Cured by Immuntherapy “Cocktail”, Reports Surviving Mesothelioma 2
... Kiwanis International made a pledge to help protect children ... first Worldwide Service Project. Now, with the majority of ... organizations, institutions and individuals to propose a project to ... , , "We live today in a world ...
... ... (AOSSM) Hall of Fame inductees, Per A.F.H Renström, MD, PhD, will be inducted into the ... , ... June 27, 2009 -- One of five 2009 American Orthopaedic Society for Sports Medicine ...
... Consumers and Workers Jubilant Over Order Halting July 1st Wage Cut ... consumers and workers reacted jubilantly Thursday evening upon hearing the news ... state of California to halt a proposed $2 an hour cut ... has the effect of stopping pay cuts in all California counties ...
... The National Autism Association (NAA) along with 12 other organizations ... raise awareness about dangerous restraint and seclusion practices in schools. ... 19th GAO Report that revealed no federal laws regulating restraint ... "widely divergent" laws in remaining states. , ...
... characters, experts say , FRIDAY, June 26 (HealthDay News) ... loss of Michael Jackson, one might think celebrity worship ... Olympus in ancient Greece to the bobby-soxers swooning over ... today, adulation of the stars is an age-old pursuit, ...
... , Wrongful firing led to doctor,s claims of slander, breach of ... who won an $8.6 million judgment against his employer two years ... in his favor. , , The Court of ... found in favor of Dr. Neal Fisher following a 2007 judgment ...
Cached Medicine News:Health News:Kiwanis International Pursuing Second Worldwide Service Project 2Health News:Kiwanis International Pursuing Second Worldwide Service Project 3Health News:Olympics Physician, Per A.F.H. Renstrom, MD, PD, Inducted into Sports Medicine Hall of Fame 2Health News:Olympics Physician, Per A.F.H. Renstrom, MD, PD, Inducted into Sports Medicine Hall of Fame 3Health News:Judge Rules on SEIU Lawsuit 2Health News:National Autism Association Teams Up With 12 Organizations to End Abusive Restraint and Seclusion in Schools 2Health News:The Psychology of Celebrity Worship 2Health News:The Psychology of Celebrity Worship 3Health News:Appeals Court OKs Multimillion-Dollar Judgment for Dallas Doctor 2
Based on the clinically proven ACS MULTI-LINK Stent, ULTRA is a coronary stent system specifically designed for use in larger vessels. This innovative system utilizes a unique stent pattern to give y...
The MULTI-LINK RX PENTA Coronary Stent Systems with new ACCESS-LINK Stent Design are indicated for improving coronary luminal diameter....
Now available in 2.75-mm diameters, the S660 small vessel coronary stent expands your treatment options for accurate sizing and precision stenting....
The MULTI-LINK PIXEL Coronary Stent System was designed to address the challenges of small vessel treatment in patients with abrupt or threatened abrupt closure (ATC)....
Medicine Products: