Navigation Links
Clinical Data Demonstrates That LYSTEDA™ Significantly Reduced Menstrual Blood Loss and Limitations on Social, Leisure and Physical Activities in Women With Cyclic HMB
Date:5/19/2010

A Meaningful Reduction in MBL

To quantify 'meaningful' reduction in MBL in women with HMB after treatment with LYSTEDA, data from 294 women in the study were used in a blinded receiver operating characteristic (ROC) analysis.  MBL was measured in two ways during the study.  One measured the blood loss using a validated alkaline hematin method at baseline and after treatment with LYSTEDA. The second measured a meaningful reduction in MBL using the Menorrhagia Impact Questionnaire (MIQ), a patient-reported outcome instrument previously validated in an HMB population.  Women in this study were asked if the change in their period after treatment was 'meaningful or important' after treatment compared to their prior pretreatment cycles.  After treatment with LYSTEDA, women with HMB perceived an MBL reduction of 36 mL or greater to be meaningful.  

Effect of LYSTEDA Treatment on Social, Leisure and Physical Activities

To measure changes in social, leisure and physical activities in women with HMB treated with LYSTEDA, women (n=294) were randomized (2:2:1) to receive LYSTEDA 1.95 g/day (n=115), LYSTEDA 3.9 g/day (n=112), or placebo (n=67) for up to five days per menstrual period for three cycles.  The MIQ was used to measure changes at baseline and after three treatment menstrual cycles.  The questionnaire contains questions about limitations on social, leisure, physical, or work activities during menstruation, and the woman's perception of the influence of MBL on those measures.  Women receiving either dose of LYSTEDA experienced significant improvements in all measurements from baseline compared with placebo (P <.01 for each dose).  Improvement in all measurements was greater in women receiving high-dose LYSTEDA compared with low-dose LYSTEDA.  Both dosage regimens were
'/>"/>

SOURCE Ferring Pharmaceuticals Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Mpex Pharmaceuticals Presents Positive Phase 2 Clinical Trial Results of Aeroquin(TM) (MP-376) Treatment in Cystic Fibrosis Patients
2. ADMIRE-HF Clinical Trial Published in the Journal of the American College of Cardiology
3. ThromboGenics and BioInvent to Receive EUR10 Million Milestone as Partner Roche Begins New Clinical Study with TB-403
4. Omeros Selects Clinical Candidate for MASP-2 Program With Potential Applicability to Multiple Inflammatory Disorders
5. 3M and CitiusTech to Integrate 3M Healthcare Data Dictionary With CitiusTechs BI-Clinical Healthcare Business Intelligence Framework
6. CrystalGenomics Announces Successful Completion of a Phase I SAD Clinical Trial for CG400549, its Novel Antibiotic Candidate
7. Somanetics Corporation Announces 24 Clinical Abstracts on INVOS System Presented at Annual Pediatric Academic Societies National Conference
8. Protege Encore Clinical Trial Evaluates New Investigational Approach For Individuals Recently Diagnosed With Type 1 Diabetes
9. Novocell Becomes ViaCyte, Inc., as it Accelerates Pre-Clinical Development of a Stem Cell Derived Treatment for Diabetes
10. Stereotaxis Updates Progress on Major Clinical Initiative Related to Electrophysiology (EP) Treatment of Ventricular Tachycardia
11. US HIFU Receives Unanimous Approval to Continue the Clinical Investigation of High Intensity Focused Ultrasound (HIFU) for Treatment of Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... , March 30, 2015  Amgen (NASDAQ: AMGN ) ... conference at 9:05 a.m. ET on Thursday, April 2, 2015, ... York City . Scott Foraker , vice president ... the conference. Live audio of the presentation can be accessed ... under Investors. A replay of the webcast will also be ...
(Date:3/30/2015)... March 30, 2015  Researchers at the Blanchette ... Joan C. Edwards School of Medicine announced their ... in a Family with Atypical AD."  An Alzheimer ... have a known variant of PSEN1, showed promising ... Genetically confirmed Alzheimer,s patients as severely advanced as ...
(Date:3/30/2015)... Texas , March 30, 2015 ... the My Diabetes Emergency Plan at the 2015 @NatHurricaneCon ... you to be prepared to manage your #diabetes before ... Endocrinology (ACE) – the charitable, educational and scientific arm ... has joined forces with Lilly Diabetes to share the ...
Breaking Medicine Technology:Amgen To Present At The Goldman Sachs Key Debates In Biosimilars Conference 2Severe Alzheimer's Patient Responds to Bryostatin Treatment 2Severe Alzheimer's Patient Responds to Bryostatin Treatment 3Severe Alzheimer's Patient Responds to Bryostatin Treatment 4Severe Alzheimer's Patient Responds to Bryostatin Treatment 5Preparation Is Personal for Those with Chronic Illnesses 2Preparation Is Personal for Those with Chronic Illnesses 3Preparation Is Personal for Those with Chronic Illnesses 4
... Lumalier Corporation announces an agreement with Philips Healthcare ... in hospitals. The distribution agreement was announced at ... in Infection Control and Hospital Epidemiology (APIC), where ... showcase the Tru-D total-room ultraviolet (UV) disinfector. ...
... LifeSciences , Inc. announced today that another United States ... Patent and Trademark Office jointly to The University of ... Department of Health and Human Services.  The patent ... exclusively to Convergen LifeSciences, Inc. The patent covers CNVN202 ...
Cached Medicine Technology:Lumalier Partners with Philips Healthcare to Provide Tru-D Solution for Reduction of Environmental Pathogens in Healthcare Facilities 2Convergen LifeSciences Announces Patent Award 2
(Date:3/31/2015)... Miraca Life Sciences, the nation’s largest ... breast pathology offering , to include critical testing ... Sciences’ breast pathology services feature:, ... approach to terminology and diagnostic criteria , ... cancer panels , Molecular tumor profiling , ...
(Date:3/31/2015)... Prong ” was featured on NewsWatch as part of its ... products available to consumers. Scott Steinberg, a technology expert and ... viewers how this phone case ensures that users will always ... phone is running out of power and they don’t have ... a solution to this problem. The PWR Case by Prong ...
(Date:3/31/2015)... Jolla, CA (PRWEB) March 31, 2015 ... mint company with a fantastic back-story. With a recent ... hit Shark Tank spin-off, Dr. Hendler’s Vitamin Mint Company embraces ... get exposure for its revolutionary product. , The Vitamin ... , author of the PDR for Nutritional Supplements, (a.k.a. the ...
(Date:3/31/2015)... Louis, MO (PRWEB) March 31, 2015 ... Washington University maternal-fetal medicine specialists at Barnes-Jewish Hospital ... member of the Southern Illinois Healthcare (SIH) system. ... Carbondale area needed a maternal-fetal medicine consultation, she ... to get an ultrasound and then talk with ...
(Date:3/30/2015)... Phoenix Strategic Performance, a human capital advisory firm ... PSP Institute. The Institute develops and delivers highly ... direct connection to applied business results. The Institute is ... Phoenix Strategic Performance Assessment and Alignment Analysis System. The ... organization’s ability to take an honest and accurate look ...
Breaking Medicine News(10 mins):Health News:Miraca Life Sciences Formalizes and Expands Breast Pathology Business 2Health News:Miraca Life Sciences Formalizes and Expands Breast Pathology Business 3Health News:The Swiss Army Knife of Phone Cases was Featured on NewsWatch Television 2Health News:What Do Mints, a World Renowned UCSD Biochemist, Vitamins and a Zany Musician Have in Common? 2Health News:Access to Maternal-fetal Experts Expands into Rural Communities 2Health News:Access to Maternal-fetal Experts Expands into Rural Communities 3Health News:Phoenix Strategic Performance Launches Human Capital Development Institute 2Health News:Phoenix Strategic Performance Launches Human Capital Development Institute 3
... of Medicine (BUSM) have found that some medical inpatients ... intervention. The BUSM study appears in the May issue ... . , "Brief intervention shows promise for increasing receipt ... cognitive functioning or an alcohol- attributable diagnosis," said lead ...
... on human genome , , THURSDAY, April 23 (HealthDay News) -- ... has succeeded in sequencing the entire genome of the placid, ... biology of this bovine and related creatures (even humans), and ... two reports in the April 24 issue of Science ...
... Harvard Medical School today announced the launch ... cancer and other prostate conditions understand the issues related ... treatment. The website, www.HarvardProstateKnowledge.org , was ... medical oncology and urologic cancer. This website is especially ...
... Keeping Michigan Workers Working!LANSING, Mich., April 23 May ... MICHIGAN will hold a summit involving 120 of Michigan,s ... Workability in Michigan, www.workabilityim.org , ... professions and organizations who are passionate about promoting safer, ...
... MR procedure that uses diffusion-weighted imaging (DWI) to determine ... benign may help reduce unnecessary breast biopsies, according to ... in Bethesda, MD. DWI is a method that produces ... compartments (diffusion). , The study included 80 patients ...
... tubo ovarian abscesses help women avoid surgery, according to ... MA. Tubo ovarian abscesses (TOAs) are an infected collection ... They can occur in patients with complicated cases of ... study included 54 TOAs in 46 patients. Results showed ...
Cached Medicine News:Health News:Researchers find medical inpatients with unhealthy alcohol use may benefit from brief intervention 2Health News:Scientists From 25 Countries Sequence Cow Genome 2Health News:Scientists From 25 Countries Sequence Cow Genome 3Health News:Harvard Medical School Prostate Disease Website Guides Patients Through Decision-Making Process 2Health News:Workability in Michigan Summit to be Held May 1 2
... Preserve your data for future generations. Most gels ... solid backing plate of our gel dryer, covering ... frame over them to hold the cellophane flat. ... frame with an open area somewhat larger than ...
... Most gels can be dried by positioning them ... dryer, covering them with wet semi-permeable cellophane and ... cellophane flat. Tut's Tombs also produce great fluorographs. ... larger than the gel to be dried. Note ...
... Preserve your data for future generations. Most gels ... solid backing plate of our gel dryer, covering ... frame over them to hold the cellophane flat. ... frame with an open area somewhat larger than ...
... Easy Breeze Air Gel Dryer : Dry up ... 24 gels 8 10 cm without a ... rapid drying, or no heat for controlled drying ... transparent, dried gels. Add and remove gels at ...
Medicine Products: