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Cleveland Clinic Leading Clinical Program to Improve Early-Stage Lung Cancer Detection
Date:11/26/2007

e chest radiologists providing subspeciality expertise and interpretation for 130,000 chest radiographs and 20,000 chest CT's annually. Twice as many chest exams are performed annually by the different regional practices of Cleveland Clinic's Imaging Institute.

About Riverain Medical

Riverain Medical, LLC is a privately-held medical software technology company headquartered in Dayton, Ohio, specializing in computer-aided detection (CAD) of diseases, such as lung cancer. The company's staff is comprised of seasoned medical advisors, regulatory and quality analysts, programmers, and managers that have spent their entire careers in healthcare. Riverain's ownership and management team have extensive experience in the medical products industry, with an emphasis on research and development and the successful commercialization of medical technologies.

Riverain has introduced the first FDA-PMA approved chest X-ray CAD product. Using conventional chest X-rays, Riverain's OnGuard(TM) system assists radiologists in identifying features associated with solitary pulmonary nodules that could represent early-stage lung cancer and require further investigation.

(1) American Cancer Society Facts & Figures 2007

(2) National Institutes of Standards and Technology, an agency of the

U.S. Commerce Department's Technology Administration

(3) Riverain Medical 2001 Clinical Trial for Food and Drug Administration

Pre-Market Approval

(4) Li, F., Engelmann, R., Metz, C. & et al (2007). Results Obtained by

a Commercial computer-aided Detection (CAD) Program with Radiologist

Missed Lung Cancer on Chest Radiographs. Radiology. In Press.

(5) White, C., Flukinger, T. & Jeudy, J. (2006). Use of a Computer-Aided

Detection System To Detect Missed Lung Cancer on Chest Radiographs.

Radiology Society of North America.

(6) Kvale, P.A. (2006). Chronic cough due to lung
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SOURCE Cleveland Clinic and Riverain Medical
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