Navigation Links
Circassia's Ragweed Allergy Therapy Achieves Positive Phase II Clinical Results
Date:3/8/2012

OXFORD, England, March 8, 2012 /PRNewswire/ --

Circassia Ltd, a specialty biopharmaceutical company focused on allergy, today announced that its ragweed allergy therapy has achieved positive results in a key phase II clinical trial.  In the study, patients with more severe symptoms achieved a significantly greater improvement following treatment with the ToleroMune® T-cell vaccine than those on placebo (p≤0.05).  The results were presented at the 2012 Annual Meeting of the American Academy of Allergy, Asthma and Immunology*.  

"The results of this key phase II study are highly encouraging, because they show our ToleroMune ragweed allergy vaccine can reduce patients' symptoms after just a short course of treatment and, most importantly, offers the greatest improvement to those who can benefit most," said Steve Harris, Circassia's CEO. "We have now achieved successful phase II results with four of our allergy T-cell vaccines, which validate our scientific approach and give us the confidence to progress our lead programmes into the final phase of development."

Circassia's latest phase II study was designed to assess the T-cell vaccine's efficacy and tolerability and to identify the optimal treatment regime.  The trial was conducted in Canada in 275 ragweed allergy patients.  During the randomised, double-blind, placebo-controlled trial, volunteers received one of four regimens of ToleroMune treatment over a three-month period.  Patients were exposed to ragweed allergens in a validated exposure chamber, and investigators compared their nasal and ocular symptoms against the pre-treatment baseline.  The results show that the T-cell vaccine's optimal regimen substantially reduced patients' symptoms, achieving a 97% greater reduction than placebo (p≤0.05) in subjects who had a moderate level of symptoms at baseline.  The treatment was safe and well tolerated in all groups.
'/>"/>

SOURCE Circassia Ltd
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Circassia Begins Phase II Clinical Trial With Ragweed Allergy Therapy
2. Cold, Flu and Allergy Sufferers Can Select the Best Over-the-Counter Medications with Help from Pharmacists
3. AllergEase LLC Launches All-Natural Lozenges for Seasonal Allergy Sufferers
4. SRI International Awarded Contract Worth Up to $100M From National Institute of Allergy and Infectious Diseases
5. Planet Biopharmaceuticals, Inc. Divests Assets of Allergy Control Products, Inc.
6. Perrigo Company to Attend the 2011 Annual Meeting of the American College of Allergy, Asthma & Immunology
7. Jubilant HollisterStier Allergy Launches Allergy Industry Insights Educational Webinar Series
8. Allegra® and Survivor Winner Danni Boatwright Want to Hear About Your "Allergy Adventures"
9. Allergy Technologies LLC Provides Over $100,000 in a Research Grant to The Ohio State University for the Study of Bed Bugs
10. Food Allergies Common among Children and Linked to Environmental Allergies and Asthma Later in Life, Suggests Largest-Ever National Allergy Study
11. Cobalis Corp. Launches National Television Commercials for PreHistin® Allergy Defense Formula
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... , Jan. 23, 2015  Northwest Biotherapeutics, Inc. (NASDAQ: ... personalized immune therapies for operable and inoperable solid tumor cancers, ... at the 7 th Annual Phacilitate Immunotherapy Forum in ... presentation at Phacilitate will take place on January 26 at ...
(Date:1/23/2015)... More than a third of reproductive-aged women enrolled in ... insurance, filled a prescription for an opioid pain medication each ... Morbidity and Mortality Weekly Report (MMWR). Opioids ... to severe pain.  They are also found in some prescription ...
(Date:1/23/2015)... , Jan. 23, 2015 /PRNewswire/-- Harwood Feffer LLP ( www.hfesq.com ... directors of Advaxis, Inc. ("Advaxis" or the "Company") (NASDAQ: ... breached its fiduciary duties to shareholders. On ... investing website reporting that Advaxis had misrepresented the clinical ...
Breaking Medicine Technology:NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3Harwood Feffer LLP Announces Investigation of Advaxis, Inc. 2
... a developer of therapeutics for disorders of women,s sexual health, ... appointment to strengthen and expand the Company,s leadership, as follows: ... of the S1 Advisory Board of Directors since October 2011 ... Molly A. Katz, MD was appointed as a member of ...
... 2012 Sosei Group Corporation ("Sosei"; TSE ... its wholly owned Japanese subsidiary, Sosei Co., Ltd., has ... the treatment of oropharyngeal candidiasis. SO-1105 was originally developed ... its first marketing authorization for SO-1105 in France in ...
Cached Medicine Technology:S1 Pharmaceuticals Announces New Executive Management and Scientific Advisory Board Appointments 2S1 Pharmaceuticals Announces New Executive Management and Scientific Advisory Board Appointments 3Sosei Announces Initiation of Phase I Study for SO-1105 2
(Date:1/22/2015)... 2015 The U.S. Pharmacopeial Convention is ... of Clinical Pharmacy Services at North Carolina State’s College ... the 2015 Beal Award for Distinguished Volunteer Service—the organization’s ... on the contributions of volunteer experts to direct its ...
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce the release of ... kids with cancer. The Chemo Duck App, available on iTunes for ... games to help children of all ages living with cancer adjust ... kids entertained, educated and at ease while waiting for clinic visits ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Blue Cross and ... Minnesotans who exemplify what it means to “Live Fearless.” ... for people to share their stories about how they or ... simply inspired others by living in the moment. By telling ...
(Date:1/22/2015)... January 22, 2015 Thousand of GranuFlo ... Care recalled its GranuFlo and NaturaLyte dialysis concentrates continue ... in U.S. District Court, District of Massachusetts, Bernstein Liebhard ... the Court has remanded a case filed by the ...
(Date:1/22/2015)... January 22, 2015 A study ... Medicine flagship journal Medicine & Science in Sports ... exercise may help reduce gastrointestinal (GI) problems associated ... , Participants in the double-blind, placebo-controlled study took ...
Breaking Medicine News(10 mins):Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 2Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 3Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 4Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3
... is not managed well in the general population and it,s ... research by St. Michael,s Hospital. Twenty-five per cent of ... six months or more. The number is likely to be ... injuries. Of the 152 residents of homeless shelters with ...
... University School of Medicine (BUSM) and Boston Medical Center ... the National Institute on Drug Abuse (NIDA), to improve ... Eastern Europe among HIV-infected Russian and Eastern European injection ... will be known as LINC, Linking Infectious and Narcology ...
... WEDNESDAY, July 20 (HealthDay News) -- Tall folks may be ... research says. Among women, the risk of breast, ovarian, ... up about 16 percent for every 4-inch bump in stature, ... increased risk of a wide range of cancers," said study ...
... released four reports that are the result of ... in the nanotechnology environmental, health, and safety (EHS) ... of an ongoing strategy to coordinate nanotechnology-related EHS ... the Federal Government to share the latest information ...
... A new study by Harvard Medical School researchers published ... Medicine finds that access to outpatient psychiatric care ... for people with reputedly excellent private health insurance. Given ... Massachusetts health reform, the findings have national implications, the ...
... Maureen Salamon HealthDay Reporter , WEDNESDAY, July ... for women in their 40s -- the topic of ... -- has drawn resounding support from the nation,s largest ... of Obstetricians and Gynecologists (ACOG) issued new guidelines calling ...
Cached Medicine News:Health News:Chronic pain in homeless people not managed well: Study 2Health News:BUSM/BMC researchers awarded $3.5 million grant from the NIDA 2Health News:Study Contends Taller People at Heightened Cancer Risk 2Health News:Study Contends Taller People at Heightened Cancer Risk 3Health News:NNI releases 4 workshop reports from the nanoEHS Series 2Health News:Even privately insured have hard time getting psychiatric care in Massachusetts: Harvard study 2Health News:Largest Ob/Gyn Group Backs Annual Mammograms in 40s 2Health News:Largest Ob/Gyn Group Backs Annual Mammograms in 40s 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: