Navigation Links
Cinryze® (C1 Esterase Inhibitor [Human]) Data Presented at 2011 American Academy of Allergy Asthma & Immunology (AAAAI) Annual Meeting
Date:3/22/2011

IV was administered within 24 hours before a procedure.  The results cited on the poster included the following:

  • Forty-one unique subjects (8 children, 33 adults) received Cinryze for 91 procedures (40 in children, 51 in adults);
  • Approximately 55 percent of procedures involved dental work and 37 percent involved surgeries or interventional diagnostic procedures.  Among the 8 children (aged 6-17 years), 90 percent of procedures involved dental work;
  • Pre-procedural administration of Cinryze prevented HAE attacks during or following 98 percent of medical, dental, or surgical procedures;
  • Only 2 HAE attacks were reported within 72 hours after dosing: 1 genitourinary attack after dental work and 1 laryngeal attack after laparoscopy. Both resolved after treatment with an additional dose of Cinryze;
  • Seven subjects reported adverse events within 7 days after receiving Cinryze; none were considered related to Cinryze by the investigator.  

In a poster entitled, 'Safety and Efficacy of Nanofiltered C1 Esterase Inhibitor (human) (Cinryze®) for the Treatment of Laryngeal Attacks in Subjects with Hereditary Angioedema (HAE),' Dr. Marc Riedl, M.D., of the University of California, Los Angeles, David Geffen School of Medicine presented the experience of 85 subjects who received Cinryze to treat 267 laryngeal attacks of HAE.  These data were compiled from all completed studies with Cinryze.  These subjects received Cinryze 1000U IV for HAE attacks; a second 1000U dose could be administered 1 hour later if necessary. The results cited on the poster included the following:

  • Across all studies, 85 unique subjects (74 adults, 11 children) received Cinryze for treatment of 267 laryngeal attacks; of them, only 1 subject required intubation;
  • Four subjects reported SAEs that were not HAE manifestations; none were consid
    '/>"/>

SOURCE ViroPharma Incorporated
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6

Related medicine technology :

1. ViroPharma Announces Positive CHMP Opinion for Cinryze® (C1 Inhibitor [Human]) in European Union
2. Cinryze® (C1 Esterase Inhibitor [Human]) Data Presented at 2010 International Scientific Conference of the World Allergy Organization (WAO)
3. ViroPharma Receives Complete Response Letter for Cinryze™ (C1 Esterase Inhibitor [Human]) Industrial Scale Supplement
4. ViroPharma Announces Publication of Cinryze™ (C1 Esterase Inhibitor [Human]) Phase 3 Trial Results in Hereditary Angioedema (HAE) in the New England Journal of Medicine
5. ViroPharma Files Prior Approval Supplement (PAS) for Cinryze™ (C1 Esterase Inhibitor [Human]) Industrial Scale Manufacturing
6. Hereditary Angioedema Patients Report: C1-Esterase Inhibitor Concentrate Effective in Treating Acute Attacks, Helps Them Avoid Emergency Care
7. PharmAthenes Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimers Disease
8. CSL Behring Submits BLA Requesting Approval of C1-Esterase Inhibitor for the Treatment of Hereditary Angioedema
9. Protalix BioTherapeutics Extends Research Agreement With Yissum Based on Promising Acetylcholinesterase Program Results in Animal Study
10. iTherX Initiates Phase 1b Study of First-in-Class Hepatitis C Virus Entry Inhibitor ITX-5061
11. N30 Pharmaceuticals to Present S-Nitrosoglutathione Reductase Inhibitor Preclinical Safety Data at 2011 Society of Toxicology 50th Anniversary Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/19/2013)... 2013 /PRNewswire-iReach/ -- Robert M. Bernstein, M.D., ... procedures and founder of Bernstein Medical – Center ... Doctors, issue of New York Magazine for the ... ) Dr. Bernstein earned his ... reputation as world-renowned hair restoration physician, through a ...
(Date:6/19/2013)... , June 19, 2013 Amgen is pleased ... United States , Canada and ... recipients of the Amgen Award for Science Teaching Excellence (AASTE). ... at the kindergarten through 12th grade level who have an ... education. With a long-standing commitment to science education, ...
(Date:6/19/2013)... , June 19, 2013 A decade-long JDRF-funded ... Helmholtz Zentrum München, Germany , is ... and the risk of developing type 1 diabetes (T1D), ... for the disease. The study, "Seroconversion to Multiple Islet ... was published today in The Journal of the ...
Breaking Medicine Technology:Dr. Robert Bernstein in NY Magazine's 'Best Doctors' Issue for 14th Consecutive Year 2Dr. Robert Bernstein in NY Magazine's 'Best Doctors' Issue for 14th Consecutive Year 3Amgen Award For Science Teaching Excellence Honors Outstanding Teachers 2Amgen Award For Science Teaching Excellence Honors Outstanding Teachers 3New Data on Islet Autoantibodies in Young Children Defines Early Type 1 Diabetes Development 2New Data on Islet Autoantibodies in Young Children Defines Early Type 1 Diabetes Development 3
... N.C., April 13, 2011 iAdvantage Software, ... solutions for managing Life Science Research and Development ... (ABC), a Contract Research Organization, headquartered in ... hosted solution to support its Ecotoxicology and other ...
... Healthcare announced interim results of a recently completed randomized ... the clinical  management and diagnosis of adult patients who ... results, presented at the 2011 American Academy of Neurology ... of DaTscan as an adjunct diagnostic tool for use ...
Cached Medicine Technology:Analytical Bio-Chemistry (ABC) Laboratories Implements eStudy™ Hosted Platform to Support its Ecotoxicology and Other Service Offerings 2Analytical Bio-Chemistry (ABC) Laboratories Implements eStudy™ Hosted Platform to Support its Ecotoxicology and Other Service Offerings 3GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 2GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 3GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 4GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 5GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 6
(Date:6/19/2013)... along with the Japanese government and the Bill ... bolster Japan,s contribution to global health through the ... a press conference held as a side event ... Development (TICAD V). , Representatives from each of ... Labour and Welfare, the Ministry of Foreign Affairs, ...
(Date:6/19/2013)... Louisiana State University have developed a method for identifying ... on understanding the genetic interaction between single nucleotide polymorphisms ... cancer,s aggressiveness to avoid unnecessary radical treatment. , ... PLOS ONE in April. , According to the ... cancers and 9 percent of cancer deaths. It is ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 Brightree LLC ... business management software solutions for the post-acute care industry, has ... - on the Healthcare Informatics 100 (HCI 100) ... companies in the U.S. in terms of revenue during the ... an average rate of 85% annually, and the company has ...
(Date:6/19/2013)... Kansas City will host its first Ciclovia event on Sept. 7, ... of Main Street in the midtown area will be restricted to ... The Main Street Corridor Development and BikeWalkKC are ... the ranks of dozens of cities across the US and Americas ... and active lifestyles. , “Ciclovia is the perfect event for the ...
(Date:6/19/2013)... Louis, MO (PRWEB) June 19, 2013 ... organization, partnered with ARAMARK Healthcare Technologies to help ... management plan with savings of more than 17 ... and maintenance service expenditures. , “Driving economies of ... top medical equipment management challenges facing multi-site providers,” ...
Breaking Medicine News(10 mins):Health News:GHIT Fund celebrates historic beginning of Japanese R&D initiative in global health 2Health News:GHIT Fund celebrates historic beginning of Japanese R&D initiative in global health 3Health News:Moffitt Cancer Center researchers identify genetic variants predicting aggressive prostate cancers 2Health News:Brightree Debuts on List of Top 100 Healthcare Technology Companies 2Health News:Brightree Debuts on List of Top 100 Healthcare Technology Companies 3Health News:Main Street Corridor Development Corporation and BikeWalkKC Partner to Host Main Street Day and Kansas City’s First Ciclovia 2Health News:Main Street Corridor Development Corporation and BikeWalkKC Partner to Host Main Street Day and Kansas City’s First Ciclovia 3Health News:Amerinet Partners with ARAMARK Healthcare Technologies to Help Pacific Medical Centers Save 17 Percent and Better Manage System-Wide Equipment Program 2
... estimated 55,000 hospitalizations were prevented in U.S., researchers say ... rotavirus greatly reduces the risk of hospitalization for acute ... a leading cause of severe diarrhea and dehydration among ... a million deaths worldwide each year. The illness was ...
... ... from Pender County Schools and Framingham Public School District , ... Santa Clara, Calif. (PRWEB) May 14, ... announced today that it will host a Webcast entitled “Learning from your Peers: 802.11n ...
... decline sharply and risk of dying increases, study finds , ... clot-busting drug alteplase (tPA) within 4.5 hours of having a ... later, Scottish doctors report. , It has been known that ... study shows for the first time that there is significant ...
... ... Medical Marijuana Dispensaries in CA, Stock is Soaring.,California company announces, after ... medical marijuana dispensaries compliant with state and local laws. The stock ... For more complete coverage on the Business of Medical Marijuana, ...
... ... is pleased to announce the introduction of the Periowave™ HHL-1000 cordless, handheld ... Association, Booth # 430 & 432. Both products represent over 10 ... ), and over 20 years pre-clinical research at University College London, England. ...
... ... brings the Legal Hold Pro™ service into doeDiscovery™. Further expanding doeLegal,s capabilities across the ... leadership role to offer increased value to all eDiscovery clients. , ... (PRWEB) May 14, 2010 ...
Cached Medicine News:Health News:Rotavirus Vaccine Helps Kids Avoid Severe Gastro Illness 2Health News:Aerohive Networks Hosts Tech & Learning Customer Webcast Focusing on Easy to Deploy 802.11n Wi-Fi 2Health News:Early Treatment With Clot-Busting Drug Best After Stroke 2Health News:Early Treatment With Clot-Busting Drug Best After Stroke 3Health News:Cannabis Medical Solutions Announces Plan to Franchise Ownership of Medical Marijuana Dispensaries in California 2Health News:Cannabis Medical Solutions Announces Plan to Franchise Ownership of Medical Marijuana Dispensaries in California 3Health News:Periowave Dental Technologies Introduces Periowave™ HHL-1000 cordless, Handheld Laser at 2010 Ontario Dental Association Spring Meeting 2Health News:doeLegal and Zapproved Sign Alliance to Add Legal Hold Pro to Suite of Powerful Online Legal Solutions 2Health News:doeLegal and Zapproved Sign Alliance to Add Legal Hold Pro to Suite of Powerful Online Legal Solutions 3
... Chalam 15° Prism are designed ... are recommended for tractional retinal ... Rhegmatogenus retinal detachment. They can ... and other midperipheral laser applications. ...
... The High-Mag 1.5x ... internal limiting membrane peeling ... optic nerve neurotomy, sheathotomy ... traditional macular edema and ...
... The MiniQuad ACS allows visualization ... ora serrata, with essentially coaxial positioning of ... excellent for retinal detachment surgery, repairing giant ... vitreoretinopathy and for examining the peripheral retina ...
... With somewhat higher magnification and ... is best suited for detailed ... The Central Retinal is ideal ... in membrane peeling in proliferative ...
Medicine Products: