Navigation Links
Cinryze® (C1 Esterase Inhibitor [Human]) Data Presented at 2011 American Academy of Allergy Asthma & Immunology (AAAAI) Annual Meeting
Date:3/22/2011

IV was administered within 24 hours before a procedure.  The results cited on the poster included the following:

  • Forty-one unique subjects (8 children, 33 adults) received Cinryze for 91 procedures (40 in children, 51 in adults);
  • Approximately 55 percent of procedures involved dental work and 37 percent involved surgeries or interventional diagnostic procedures.  Among the 8 children (aged 6-17 years), 90 percent of procedures involved dental work;
  • Pre-procedural administration of Cinryze prevented HAE attacks during or following 98 percent of medical, dental, or surgical procedures;
  • Only 2 HAE attacks were reported within 72 hours after dosing: 1 genitourinary attack after dental work and 1 laryngeal attack after laparoscopy. Both resolved after treatment with an additional dose of Cinryze;
  • Seven subjects reported adverse events within 7 days after receiving Cinryze; none were considered related to Cinryze by the investigator.  

In a poster entitled, 'Safety and Efficacy of Nanofiltered C1 Esterase Inhibitor (human) (Cinryze®) for the Treatment of Laryngeal Attacks in Subjects with Hereditary Angioedema (HAE),' Dr. Marc Riedl, M.D., of the University of California, Los Angeles, David Geffen School of Medicine presented the experience of 85 subjects who received Cinryze to treat 267 laryngeal attacks of HAE.  These data were compiled from all completed studies with Cinryze.  These subjects received Cinryze 1000U IV for HAE attacks; a second 1000U dose could be administered 1 hour later if necessary. The results cited on the poster included the following:

  • Across all studies, 85 unique subjects (74 adults, 11 children) received Cinryze for treatment of 267 laryngeal attacks; of them, only 1 subject required intubation;
  • Four subjects reported SAEs that were not HAE manifestations; none were consid
    '/>"/>

SOURCE ViroPharma Incorporated
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. ViroPharma Announces Positive CHMP Opinion for Cinryze® (C1 Inhibitor [Human]) in European Union
2. Cinryze® (C1 Esterase Inhibitor [Human]) Data Presented at 2010 International Scientific Conference of the World Allergy Organization (WAO)
3. ViroPharma Receives Complete Response Letter for Cinryze™ (C1 Esterase Inhibitor [Human]) Industrial Scale Supplement
4. ViroPharma Announces Publication of Cinryze™ (C1 Esterase Inhibitor [Human]) Phase 3 Trial Results in Hereditary Angioedema (HAE) in the New England Journal of Medicine
5. ViroPharma Files Prior Approval Supplement (PAS) for Cinryze™ (C1 Esterase Inhibitor [Human]) Industrial Scale Manufacturing
6. Hereditary Angioedema Patients Report: C1-Esterase Inhibitor Concentrate Effective in Treating Acute Attacks, Helps Them Avoid Emergency Care
7. PharmAthenes Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimers Disease
8. CSL Behring Submits BLA Requesting Approval of C1-Esterase Inhibitor for the Treatment of Hereditary Angioedema
9. Protalix BioTherapeutics Extends Research Agreement With Yissum Based on Promising Acetylcholinesterase Program Results in Animal Study
10. iTherX Initiates Phase 1b Study of First-in-Class Hepatitis C Virus Entry Inhibitor ITX-5061
11. N30 Pharmaceuticals to Present S-Nitrosoglutathione Reductase Inhibitor Preclinical Safety Data at 2011 Society of Toxicology 50th Anniversary Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... , Oct. 1, 2014 NeuroCall, Inc., ("NeuroCall") ... for its Telestroke and Teleneurology services. Dr. Ricardo ... commented, "We are extremely proud that our quality of ... we continue to provide lifesaving support and continuity of ... hospitals throughout the United States ." ...
(Date:10/1/2014)... 2014  Varian Medical Systems (NYSE: VAR ... the fourth quarter of fiscal year 2014 following the ... The news release will be followed by a teleconference ... The news release and a link to the conference ... at: www.varian.com/investor .  To access the teleconference call ...
(Date:10/1/2014)... 2014  Express Scripts (NASDAQ: ESRX ) ... Scripts Medicare ® Prescription Drug Plans (PDP) will ... WAG ) (NASDAQ: WAG ), ... support  for their Medicare dollars. Medicare beneficiaries ... or Choice plans for 2015 can ...
Breaking Medicine Technology:NeuroCall Awarded Joint Commission Accreditation 2Varian Medical Systems Schedules Fourth Quarter FY2014 News Release and Conference Call 2Express Scripts Collaborates with Walgreens to Create Value-Driven Medicare Prescription Drug Plan Pharmacy Network 2Express Scripts Collaborates with Walgreens to Create Value-Driven Medicare Prescription Drug Plan Pharmacy Network 3Express Scripts Collaborates with Walgreens to Create Value-Driven Medicare Prescription Drug Plan Pharmacy Network 4
... The U.S. Food and Drug Administration today announced ... Centers of Excellence in Regulatory Science and Innovation (CERSI). ... centers, which will be located at the University of ... and training needed to modernize and improve the ways ...
... Preserve Community Pharmacy Access NOW! (PCPAN) coalition ... Americans from increased costs and decreased access to quality ... Scripts Inc. and Medco Health Solutions Inc., two pharmacy ... on the coalition,s website, outlines the negative impact of ...
Cached Medicine Technology:FDA Invests $2 Million in Partnerships Through Centers of Excellence in Regulatory Science and Innovation 2Nationwide Coalition Issues 'Call To Action' To Stop Express Scripts/Medco Merger 2
(Date:10/1/2014)... 1, 2014 Patients with increased inflammation, including ... greatly increased risk of depression. For example, a ... hepatitis C virus infection causes depression in approximately ... more commonly known as fish oil, have a ... risk of heart disease and reducing triglyceride levels. ...
(Date:10/1/2014)... Insuranceragents.info has released a new blog ... plan for vulnerable family members. , Life insurance plans ... in the family should always carry a life insurance ... the rest of the family. , Clients can ... more from temporary coverage or from a permanent policy. ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 ... networking and relationship-marketing firm, announced today the ... Executive® and Project of the Year Awards ... makers representing organizations in financial services, commercial, ... large-scale technology endeavors that address key issues ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Between 23 ... in the U.S., according to figures from the National ... Diseases Association (AARDA), and many of them have something ... of having undiagnosed celiac disease. Gluten Free Therapeutics, ... awareness of undiagnosed celiac disease by publishing a series ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Scientists at ... three drugs that target immune system proteins has the ... has just posted details of the new study on ... now. , Researchers in the UWA School of ... anti-CTLA-4 drugs to mice with mesothelioma with promising results. ...
Breaking Medicine News(10 mins):Health News:Omega-3 fatty acids may prevent some forms of depression 2Health News:Life Insurance for Families - Clients Can Compare Affordable Rates Online! 2Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 2Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 3Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 4Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 5Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 6Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 7Health News:Informative New Blog Series Underscores Link Between Celiac Disease and Other Autoimmune Disorders 2Health News:Informative New Blog Series Underscores Link Between Celiac Disease and Other Autoimmune Disorders 3Health News:New Mesothelioma Study Says Mice Cured by Immuntherapy “Cocktail”, Reports Surviving Mesothelioma 2
... journal Science that a team of Californian researchers have claimed ... plays an important role in making microscopic worms live longer//. ... equation, the longer you live, the greater your chances of ... is believed that a key element in determining whether a ...
... needs no treatment. Infants aging a few days may get baby ... ,It appears as red or white bumps/spots, from the stage ... infant. // Baby acne typically occurs on the face and chest. ... ointments or creams when it typically appears on face and chest ...
... in the June 2006 issue of the International Journal ... American Society //for Therapeutic Radiology and Oncology, says that ... partial radiation for the breast in order to combat ... ,A seroma is retention of fluid in ...
... up four super speciality hospitals in four zones of the ... covered under its scheme//. ,'These facilities will be ... Mumbai or Pune,' ESI director general Ramesh Inder Singh said ... be totally new ones or existing ESI hospitals would be ...
... latest cookbook by Britain-based celebrity chef Mridula Baljekar, has ... Asian Cuisine Cookbook' category//. ,Baljekar, who runs the ... the award at a star-studded ceremony in Kuala Lumpur, ... ,'I am absolutely overwhelmed and highly honoured ...
... and sexual dysfunction may find Viagra a good option ... express improved sexual enjoyment, orgasm and a less painful ... sexual dysfunction caused by vaginal dryness, and several other ... University of Catania in Italy, have said that the ...
Cached Medicine News:
Injection Cannula, Angled; 20g (0.90) x 1" (25mm); Tip Extension: 5mm, 30g (0.30); Angled at 45°, 2.5mm from Tip....
...
...
Lacrimal Cannula, Straight, Stepped DownSize: 19g x 1-1/2"....
Medicine Products: