Navigation Links
Cimzia® (certolizumab pegol) Data Showed Rapid Improvement in Signs and Symptoms Predicted Better Long-Term Outcomes in Rheumatoid Arthritis Patients
Date:5/10/2011

BRUSSELS, May 10, 2011 /PRNewswire/ -- UCB announced today results from a post hoc analysis of the RAPID 1 study published in the Journal of Rheumatology. The results suggest moderate to severe rheumatoid arthritis (RA) patients treated with Cimzia® (certolizumab pegol), the only approved PEGylated anti-TNF, together with methotrexate (MTX), achieved a rapid response associated with improved long-term outcomes one year after treatment began.

"These results are consistent with a growing body of clinical evidence that suggest a potential for healthcare professionals to predict clinical success as early as week 12 when treating rheumatoid arthritis patients with certolizumab pegol," said lead investigator Edward Keystone, M.D., The Rebecca MacDonald Center for Arthritis, Mount Sinai Hospital, The University of Toronto. "The data supports the importance of monitoring for a rapid response, in line with recently published EULAR recommendations, and the need to consider treatment adjustments in those patients who have not achieved a clinical response at 12 weeks regardless of their treatment."

Rapid response rates following treatment with certolizumab pegol were achieved across various clinical response measures, including good/moderate EULAR response rates at weeks 6 and 12 (67.4% and 77.6% respectively versus 27.0% and 29.1% for placebo) based on this post hoc analysis. Similarly, ACR20 rates were 51.3% and 63.8% in patients treated with certolizumab pegol versus 18.2% and 18.3% for placebo at week 6 and 12 respectively.

Using the disease activity score, DAS28[ESR] greater than or equal to 1.2 responder definition, a higher proportion of patients treated with certolizumab pegol (75.8%) responded at week 12 compared to placebo (27.5%). Results suggest that a higher proportion of patients treated with certolizumab pegol who responded at week 12, achieved DAS28 low disease activity (LDA) at 52 weeks compared with patients who did not (37
'/>"/>

SOURCE UCB
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. Cimzia® (certolizumab pegol) Data Showed Broad and Rapid Relief From Burden of Symptoms In Rheumatoid Arthritis Patients
2. New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA)
3. Rapid and Long-term Clinical Responses Observed in Rheumatoid Arthritis Patients Taking Cimzia® (certolizumab pegol), According to Data Being Highlighted During ACR Meeting
4. UCB Presents Growing Body of Long-term Efficacy Data at ACG 2010 Meeting to Further Support Treatment with Cimzia® (certolizumab pegol) in Multiple Patient Populations with Moderate to Severe Crohns Disease
5. Long-Term Data on Cimzia® (certolizumab pegol) for Moderate to Severe Crohns Disease to be Highlighted at ACG Meeting
6. New Data Show CIMZIA(R) (certolizumab pegol) Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients
7. CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years
8. CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohns Disease Patients
9. CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohns Patients
10. CIMZIA(R) (certolizumab pegol), Significantly Reduces Structural Damage and Rheumatoid Arthritis Signs & Symptoms for Up to One Year
11. New Subanalyses of the RE-LY Trial Showed Pradaxa Reduced Stroke Risk in Patients With Varying CHA2DS2-VASc Scores and Types of Non-Valvular Atrial Fibrillation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)...  Membership in Medicare Supplement plans continued to ... Strategy report released by Mark Farrah Associates (MFA).  ... Med Supp plans, covered approximately 11.2 million seniors ... from 2013. Between 2013 and 2014, enrollment in ... Though UnitedHealth was the segment growth leader, many ...
(Date:5/6/2015)... , May 05, 2015 Research and Markets ... addition of the "Chromatography (Instruments and Reagents) ... to their offering. Chromatography is an ... the component of a complex mixture by differential ... decades the scientists have considered chromatography as an ...
(Date:5/6/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/4fgrnh/asiapacific ) ... Internal Trauma Fixation Devices Market by Type & ... report to their offering. The ... to grow at a CAGR of 6.7% from ... rising incidences of road accidents, increasing aging population, ...
Breaking Medicine Technology:Continued Growth in Med Supp Market for 2014 according to Mark Farrah Associates 2Global Chromatography (Instruments and Reagents) Market 2015 - Forecasts to 2019 2Asia-Pacific Internal Trauma Fixation Devices (Internal Trauma Fixation Plates, Screws, Rod Wires & Pins, Fusion Nails) Market 2015 2
... , , ATLANTA , Feb. ... for Economic and Clinical Health (HITECH) Act, Elekta has expanded its ... advantage of the financial incentives available from the federal government. These ... certified EMR systems who are able to demonstrate meaningful use. , ...
... , PITTSBURGH , Feb. 4 Mylan ... by Pfizer in connection with the filing of an Abbreviated New ... for Amlodipine Besylate and Atorvastatin Calcium Tablets 2.5/10 mg, 2.5/20 mg, ... mg, 10/20 mg, 10/40 and 10/80 mg. This product is the ...
Cached Medicine Technology:Elekta Expands Consultative Services Program to Help MOSAIQ Customers Demonstrate Meaningful Use Guidelines 2Elekta Expands Consultative Services Program to Help MOSAIQ Customers Demonstrate Meaningful Use Guidelines 3Mylan Confirms First-to-File Patent Challenge Relating to Caduet(R) 2
(Date:5/7/2015)... May 07, 2015 When people think about ... consideration to their roofs than their basements. However, heavy rain ... in crawlspaces and basements. While flooding is an obvious problem ... crawlspaces and unfinished areas dry to avoid a musty ... Damp Basement, Even small amounts of water can cause foundation ...
(Date:5/7/2015)... 07, 2015 Five CHI Health ... Health Bergan Mercy, CHI Health Immanuel and CHI ... in Papillion, Neb.; and CHI Health Mercy in ... achieving high-quality standards of care by the Accreditation ... to best practices in cardiovascular care. The five ...
(Date:5/6/2015)... 2015 Device Patent Law Changes:, Six Key ... a.m. – 12:30 p.m. EDT, http://www.fdanews.com/DevicePatentLaw , Every ... lawsuits and claims that waste their time. , It ... could be prevented if devicemakers better understand the trouble spots ... and revisions to patent laws from all around the world. ...
(Date:5/6/2015)... the exclusive hospital of the Tampa Bay Buccaneers, Florida Hospital ... James Stadium for all the “Bucs Babies” celebrating their first ... the “Bucs Babies” program last year. , “It is ... those born at the Florida Hospitals here in our community, ... enjoyed my time participating in the festivities, interacting with the ...
(Date:5/6/2015)... 06, 2015 On April 27, 2015, ... Plastic Surgery ,” compiled quotes about cosmetic surgery from ... pop singer Iggy Azalea, and Gwyneth Paltrow. For the ... having plastic surgery themselves; only a couple ... its expectations of youth and beauty. (see: goo.gl/wSomih) , ...
Breaking Medicine News(10 mins):Health News:Spring Storms Bring Musty Smell Inside 2Health News:Spring Storms Bring Musty Smell Inside 3Health News:Five CHI Health Facilities in Nebraska, Iowa Recognized for High-Quality Care by Accreditation for Cardiovascular Excellence 2Health News:Five CHI Health Facilities in Nebraska, Iowa Recognized for High-Quality Care by Accreditation for Cardiovascular Excellence 3Health News:FDAnews Announces — Device Patent Law Changes: Six Key Areas of Concern Webinar, May 27, 2015 2Health News:FDAnews Announces — Device Patent Law Changes: Six Key Areas of Concern Webinar, May 27, 2015 3Health News:Florida Hospital and the Tampa Bay Buccaneers Celebrate “Bucs Babies” Who are Turning One this Month with a Party on the Pirate Ship 2Health News:Florida Hospital and the Tampa Bay Buccaneers Celebrate “Bucs Babies” Who are Turning One this Month with a Party on the Pirate Ship 3Health News:Plastic Surgery: Sixteen Celebrities Offer their Opinion about Going Under the Knife 2
... 1 Skin damage. If,you are over 40, your skin ... as a smoker (lip lines), those long, lazy sun-worshipping summers,(dry, ... a little more of Mom and Pop in the mirror ... seeing is normal skin aging, but most of it is,likely ...
... to Fujifilm,s ... broad DR product line, STAMFORD, Conn., ... the FDA 510(k) clearance of its newest Fuji DR,(FDR) system, the ... system that can perform a variety of exams with,only one detector. ...
... BOULDER, Colo., Feb. 29 The National Patient,Safety ... Road Taken,Together," stresses the importance of improving healthcare ... and communities., Supporting National Patient Safety Awareness ... (Amex: ECI ) urges communities to,actively partner ...
... the odds? Today, at,Gulf Coast Medical Center in Panama City, ... Year babies. That news may not make,headlines, but consider the ... Joe, Florida and their husbands work together at the,Port St. ... were together helping put out a hotel fire when they ...
... how certain proteins, including,Hax1, work and how ... Tenn., Feb. 29 Investigators at St.,Jude Children,s ... that,protects certain cells from undergoing apoptosis, also known ... apoptosis is important to,researchers seeking ways to control ...
... Plans to Separate Medical ... Funeral Services Businesses, BATESVILLE, Ind., Feb. 29 Hillenbrand,Industries, ... it has,commenced a cash tender offer to purchase any and ... No. 431573AD6), of which $250,million in aggregate principal amount was ...
Cached Medicine News:Health News:The DOT CO2 Fractional: The Next Step in Laser Skin Resurfacing 2Health News:The DOT CO2 Fractional: The Next Step in Laser Skin Resurfacing 3Health News:The DOT CO2 Fractional: The Next Step in Laser Skin Resurfacing 4Health News:Fujifilm Receives FDA Approval for Unity SpeedSuite(TM) 2Health News:Fujifilm Receives FDA Approval for Unity SpeedSuite(TM) 3Health News:Encision Supports National Patient Safety Awareness Week 2Health News:St. Jude Researchers Find Key Step in Programmed Cell Death 2Health News:St. Jude Researchers Find Key Step in Programmed Cell Death 3Health News:Hillenbrand Industries, Inc. Announces 'Any and All' Cash Tender Offer for Its 4.50 percent Senior Notes Due 2009 2Health News:Hillenbrand Industries, Inc. Announces 'Any and All' Cash Tender Offer for Its 4.50 percent Senior Notes Due 2009 3Health News:Hillenbrand Industries, Inc. Announces 'Any and All' Cash Tender Offer for Its 4.50 percent Senior Notes Due 2009 4Health News:Hillenbrand Industries, Inc. Announces 'Any and All' Cash Tender Offer for Its 4.50 percent Senior Notes Due 2009 5
Curved shafts with 2 mm angled platform. Wide serrated handle with dull finish....
Straight shafts with fine tips and dull finish. Insulated stop with tip gap set at 0.3 mm. Smooth handle....
Straight shafts with micro tips and sandblast finish. Insulated smooth handle....
Straight shafts with rounded tips. Smooth handle with dull finish....
Medicine Products: