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Chronic Obstructive Pulmonary Disease (COPD) Market to 2019 - Highly-Priced New Combination Products Forecast to Capture Significant Market Share and Drive Growth

8211; Boehringer Ingelheim 19

3.1.10 Relvar/Breo – GlaxoSmithKline/Theravance 20

3.1.11 Heat Map – Marketed Products Overview 21

4 COPD Pipeline 23

4.1 Overview 23

4.2 Mechanisms of Action in the Pipeline 25

4.3 Clinical Trials 27

4.3.1 Failure Rate 27

4.3.2 Clinical Trial Duration 33

4.3.3 Clinical Trial Size 35

4.4 Promising Pipeline Molecules 38

4.4.1 Umeclidinium Bromide – GlaxoSmithKline 38

4.4.2 Umeclidinium Bromide + Vilanterol – GlaxoSmithKline/Theravance 38

4.4.3 Vilanterol Trifenatate – GlaxoSmithKline/Theravance 39

4.4.4 Olodaterol + tiotropium – Boehringer Ingelheim 39

4.4.5 TD-4208 – Theravance 40

4.4.6 QVA-149 – Novartis 40

4.4.7 Andolast (CR 2039) – Rottapharm | Madaus 41

4.5 Heat Map of Safety and Efficacy for Pipeline and Marketed Products 41

5 Market Forecast to 2019 47

5.1 Geographical Markets 47

5.1.1 Global Market 49

5.1.2 United States 51

5.1.3 Top Five Countries of Europe 54

5.1.4 Japan 58

5.2 Drivers and Barriers for the COPD Market 60

5.2.1 Drivers 60

5.2.2 Barriers 61

6 Strategic Consolidations 62

6.1 Major Co-development Deals 62

6.1.1 Galapagos Enters into Strategic Alliance with Roche 63

6.1.2 Five Prime Therapeutics Enters into Co-development Agreement with GlaxoSmithKline 63

6.1.3 Forest Labs Enters into Co-development Agreement with Nycomed 63

6.2 Major Licensing Deals 64

6.2.1 Orexo Enters into Licensing Agreement with Ortho-McNeil-Janssen and Janssen Pharmaceutica 67

6.2.2 Mundipharma Enters into Licensing Agreement with SkyePharma 68

6.2.3 Evotec Enters into Licensing Agreement with Zhejiang Conba Pharma for EVT 401 68


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