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Chronic Kidney Disease: Reducing Risks of Progression-- Prismic Pharmaceuticals Secures Exclusive Licensing Rights
Date:6/13/2013

SCOTTSDALE, Ariz., June 13, 2013 /PRNewswire/ -- Prismic Pharmaceuticals, Inc., a Scottsdale, Arizona-based pharmaceutical company, today announced that it has secured exclusive licensing rights to Palmitoylethanolamide (PEA), including the micronized and ultra-micronized forms, a novel non-steroidal, kidney-friendly anti-inflammatory and anti-fibrotic agent with a well-documented safety profile in humans.

Commenting on securing the rights to this important new agent, Prismic's Chief Medical Officer, Dr, Teo Forcht Dagi, said, "Inflammation and oxidative stress play a key role in the induction and the progression of Chronic Kidney Disease (CKD).  This is particularly so in diabetic patients, and it is most likely that inflammation is a major factor in the pathogenesis and progression of diabetic nephropathy. In addition, an increase in inflammatory cytokine levels in diabetes may increase oxidative stress as renal injury becomes more pronounced, thereby establishing a vicious cycle. Prismic, therefore, plans to undertake further clinical development with PEA to prove the concept that this molecule is capable of interrupting this cycle without adversely affecting renal function."

Dr. Forcht Dagi also went on to point out that it is believed that "by reducing low grade chronic inflammation and by inhibiting oxidative stress, PEA may reduce risk factors associated with the  progression of Chronic Kidney Disease (CKD) and have the potential to offer significant benefit to patients with CKD at early and, quite possibly, even at late stages of the disease."

Prismic Pharmaceuticals has secured worldwide licensing rights (with the exception of Italy and Spain) for PEA from the Epitech Group SRL, and has rights in all regulatory categories for CKD.  Epitech's CEO, Raffaella della Valle, commented that
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SOURCE Prismic Pharmaceuticals, Inc.
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