Navigation Links
Chimerix Presents Data Highlighting Burden Of Care Associated With Current Antiviral Therapies In Stem Cell Transplantation
Date:9/21/2012

hile the currently available antiviral agents are associated with significant adverse events, including cytopenias, nephrotoxicity, electrolyte imbalances, and others, it cannot be determined from this retrospective analysis the degree to which a specific antiviral may have contributed to the occurrence or severity of any particular AE.

Unmet Medical and Economic Needs
It is widely accepted that viral infections, including CMV, adenovirus (AdV) and BK virus (BKV) infections, cause significant morbidity and mortality in HSCT recipients.  These data shed light on the unmet medical needs associated with the current standard of care, preemptive therapy, and on the limitations of currently available antiviral agents.

In addition to the impact on morbidity and mortality, preemptive therapy dramatically increases the already significant costs associated with transplantation.  The need for intervention and management of AEs, including hospitalization and the employment of expensive antivirals, antibiotics, antifungals and colony stimulating factors, place additional strains on an already over-burdened health care system.

Data from CMX001 Study 201
The data was presented by Herve Mommeja-Marin, M.D., Vice President of Clinical Research at Chimerix.  According to Dr. Mommeja-Marin,

"There is a clear and unmet medical need for new antiviral compounds with improved safety, efficacy, and health economic profiles.  An ideal antiviral will be sufficiently safe and effective to allow for the prophylactic administration of the drug to all at-risk patients, preventing infection from occurring and avoiding the morbidity, mortality, and costs associated with preemptive therapy." 

In an effort to meet these significant medical and economic needs, Chimerix is developing CMX001, a novel broad-spectrum antiviral with activity against double-stranded DNA (dsDNA) viruses. These viruses
'/>"/>

SOURCE Chimerix, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Chimerix Signs Worldwide License Agreement With Merck For CMX157, A Novel Candidate For The Treatment Of HIV
2. Chimerixs Broad Spectrum Antiviral Therapeutic, CMX001, Demonstrates Potential To Mitigate BK Virus Associated End-Organ Disease In Clinical Study
3. Chimerix Announces BK Virus Data In Late-Breaking Poster Session At The 24th International Congress Of The Transplantation Society
4. Jennerex Presents Positive Clinical Data from Phase 2 Trial of JX-594 in Sorafenib-Refractory Liver Cancer Patients
5. Sorbent Therapeutics Presents CLP1001 Phase 2a Study Results at the 16th Annual Meeting of the Heart Failure Society of America
6. Mettler Toledo Presents In-depth Guidance to Comply with New USP Chapters 41 and 1251 on Balances Used for Quantitative Analysis in the Pharma QC Lab
7. Elevation Pharmaceuticals Presents Positive Phase 2b Results for EP-101 in COPD Patients at the European Respiratory Society Annual Congress
8. Informex Global Pharma Sourcing 2012 Presents Key Strategies & Insight For Business Success
9. Epigenomics Presents Significant Opportunities for Investment and Product Development, According to New Biotech Market Research
10. Cardium Presents Second Quarter 2012 Financial Results And Reports On Recent Developments
11. Inovio Initiates H1N1 Universal Influenza Vaccine Clinical Trial Targeting Over-65 Population, Which Represents 90% of Flu Deaths
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... The number of people overdosing from opioid ... Twenty-three percent of the workforce has misused prescription painkillers, ... Health, making opioid use a serious threat to employee ... the correct dosage with a valid prescription, subtle impairment ... National Safety Council released a guide for employers, ...
(Date:7/22/2014)... TOTOWA, N.J. , July 22, 2014 ... Florida,s first 3-way Kidney Paired Donation ... landmark surgical procedures happened on July 9 at the ... Miami, Fla. ... pairs who are not compatible for kidney transplant with ...
(Date:7/22/2014)... Elekta (NSE:EKTAb) and Royal Philips ... Foundation Trust ( Manchester, UK ), a ... is to develop the clinical value of an integrated ... a system would, in principle, improve the practice of ... "The Christie was an essential participant in the ...
Breaking Medicine Technology:5 things employers should know about prescription painkiller use 25 things employers should know about prescription painkiller use 3BiologicTx Paired Donation Aids In Successful Kidney Transplants 2BiologicTx Paired Donation Aids In Successful Kidney Transplants 3The Christie Hospital joins Elekta and Philips research consortium to develop MRI-guided radiation therapy system for cancer treatment 2The Christie Hospital joins Elekta and Philips research consortium to develop MRI-guided radiation therapy system for cancer treatment 3The Christie Hospital joins Elekta and Philips research consortium to develop MRI-guided radiation therapy system for cancer treatment 4
... for maintaining a healthy immune systemPURCHASE, N.Y., Jan. 6 ... Cancer (60(5), 643-651) by researchers at Kansai Medical ... Hexose Correlated Compound) enhances immune function by increasing the ... part of the immune system responsible for presenting foreign ...
... 6 Pacira Pharmaceuticals, Inc., an,acute care specialty ... in two pivotal Phase III SIMPLE trials to ... administration of EXPAREL(TM),(DepoBupivacaine) for prolonged postoperative analgesia. , ... in hemorrhoidectomy and in total knee,arthroplasty (TKA) are ...
Cached Medicine Technology:Study Demonstrates that AHCC(R) Enhances Immune System by Increasing the Production of Key Dendritic Cells 2Study Demonstrates that AHCC(R) Enhances Immune System by Increasing the Production of Key Dendritic Cells 3Phase III Studies of EXPAREL(TM) (DepoBupivacaine) from Pacira Complete Enrollment 2Phase III Studies of EXPAREL(TM) (DepoBupivacaine) from Pacira Complete Enrollment 3
(Date:7/22/2014)... July 22, 2014 The Restful Jaw ... the Restful Jaw ®. The FDA-registered external device ... while minimizing jaw pain, fatigue and soreness during dental ... treatment times when patients do not need to take ... The Restful Jaw is a vital solution in helping ...
(Date:7/22/2014)... University of the Pacific's Arthur A. ... of its state-of-the-art, $151 million campus this month. The ... San Francisco's South of Market (SoMa) district and houses ... patients will now be greeted by a wall of ... , Advanced Kiosks engineering team designed custom software to ...
(Date:7/22/2014)... HealthDay Reporter , MONDAY, July 21, 2014 (HealthDay ... high school may take fewer health risks than their peers ... of low-income Los Angeles teens, found that those who attended ... binge-drink, have multiple sex partners or take certain other health ... kids" being more likely to go to good schools, researchers ...
(Date:7/22/2014)... 21, 2014) Investigators at the Cedars-Sinai Samuel ... multistep investigational treatment for one of the most ... advanced pancreatic cancer. , Locally advanced pancreatic ... solid tumor, with a cumulative five-year survival rate ... disease. Surgery is rarely an option for patients ...
(Date:7/22/2014)... like electroconvulsive therapy (ECT) and transcranial magnetic stimulation ... depression. Like antidepressant medications, however, they typically have ... receive several weeks of regular ECT treatments before ... is an impetus to develop antidepressant treatments that ... stimulation (LFMS) is one such potential new treatment ...
Breaking Medicine News(10 mins):Health News:Introducing the Restful Jaw – The Only Device Designed to Protect the Patient’s Jaw 2Health News:Introducing the Restful Jaw – The Only Device Designed to Protect the Patient’s Jaw 3Health News:iKiosks Are Gateway to Premier Dental Facility 2Health News:iKiosks Are Gateway to Premier Dental Facility 3Health News:Good Schools May Be Good for a Teen's Health, Too 2Health News:Good Schools May Be Good for a Teen's Health, Too 3Health News:Unique study focuses on combined treatment approach for locally advanced pancreatic cancer 2Health News:Unique study focuses on combined treatment approach for locally advanced pancreatic cancer 3Health News:Low strength brain stimulation may be effective for depression 2
... who take a multivitamin pill may think they can smoke ... of cigarettes, according to a new study. Researchers found ... reduce their risk of cancer, allowing them to light up ... virtuous behavior for a subsequent indulgence, known as the "licensing ...
... 4 (HealthDay News) -- People living in a region of ... known to have significantly higher rates of stroke deaths than ... are also at greater risk for sepsis, a severe illness ... examined death rates from sepsis across the United States," said ...
... Duke University Medical Center and Johns Hopkins University could ... therapy to treat the second most common type of ... for the primary cancer genes involved in the development ... the probable mutations, but not the particular gene information. ...
... , THURSDAY, Aug. 4 (HealthDay News) -- A ... common form of brain cancer appears to reveal the biological ... map by sequencing protein-coding genes in seven samples of tissue ... genes (CIC and FUBP1) not previously associated with those types ...
... Spanish . , Kidney transplant from a living donor, ... those affected by particular conditions, results in increased organ survival ... the mid-90 despite the high rate of cadaveric donation. According ... living donor kidney transplants were made, which represents 11% of ...
... U.S. meat processor Cargill announced late Wednesday that it was ... about 36 million pounds of ground turkey linked to an ... closer to the source of the outbreak, which the U.S. ... Californian and sickened at least 76 others across 26 states ...
Cached Medicine News:Health News:Smokers Mistakenly Believe Vitamins Protect Them From Cancer 2Health News:U.S. 'Stroke Belt' May Also Be 'Sepsis Belt' 2Health News:Elusive gene mutations found for malignant brain tumor 2Health News:Scientists May Have Found Missing Link to Common Brain Cancer 2Health News:Minimal scar techniques in living donors for kidney transplant 2Health News:Minimal scar techniques in living donors for kidney transplant 3Health News:Minimal scar techniques in living donors for kidney transplant 4Health News:Minimal scar techniques in living donors for kidney transplant 5Health News:Cargill Begins Massive Recall of Turkey Linked to Salmonella Outbreak 2Health News:Cargill Begins Massive Recall of Turkey Linked to Salmonella Outbreak 3
MicroAmp Full Plate Covers, which are manufactured from PCR-compatible rubber, are non-sterile, autoclavable and guaranteed reusable up to five times....
96-Well PCR Plate Sealing Mat...
Inquire...
Inquire...
Medicine Products: